sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1fkw	PUR	Adenosine deaminase	3.5.4.4

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1fkw	PUR	Adenosine deaminase	3.5.4.4	1.000
2ada	HPR	Adenosine deaminase	3.5.4.4	0.668
1fkx	PRH	Adenosine deaminase	3.5.4.4	0.557
1a4l	DCF	Adenosine deaminase	3.5.4.4	0.546
1wxy	FRK	Adenosine deaminase	3.5.4.4	0.518
1uio	HPR	Adenosine deaminase	3.5.4.4	0.517
1uml	FR4	Adenosine deaminase	3.5.4.4	0.513
1qxl	FR8	Adenosine deaminase	3.5.4.4	0.509
1ndz	FR5	Adenosine deaminase	3.5.4.4	0.499
1ndy	FR3	Adenosine deaminase	3.5.4.4	0.485
1o5r	FR9	Adenosine deaminase	3.5.4.4	0.485
2z7g	EH9	Adenosine deaminase	3.5.4.4	0.463