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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.62

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.621.000
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.673
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.492
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.470
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.444