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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1fdrFADFerredoxin--NADP reductase1.18.1.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1fdrFADFerredoxin--NADP reductase1.18.1.21.000
3fpkFADFerredoxin-NADP reductase/0.607
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.574
2vnjFADNADPH:ferredoxin reductase/0.560
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.557
1f20FADNitric oxide synthase, brain1.14.13.390.556
2ok8FADFerredoxin--NADP reductase, apicoplast/0.545
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.536
2bgiFADNADPH:ferredoxin reductase/0.533
3qfsFADNADPH--cytochrome P450 reductase/0.532
1gvhFADFlavohemoprotein/0.525
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.525
1w87FADFerredoxin--NADP reductase1.18.1.20.519
1a8pFADFerredoxin--NADP reductase/0.517
1ja1FADNADPH--cytochrome P450 reductase/0.516
3w5uFADFerredoxin/0.516
4fk8FADFerredoxin--NADP reductase/0.515
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.514
1w35FADFerredoxin--NADP reductase1.18.1.20.513
3vo2FADFerredoxin--NADP reductase/0.512
1gawFADFerredoxin/0.511
1qh0FADFerredoxin--NADP reductase1.18.1.20.511
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.510
1tllFADNitric oxide synthase, brain1.14.13.390.504
2b5oFADFerredoxin--NADP reductase1.18.1.20.504
1gjrFADFerredoxin--NADP reductase1.18.1.20.503
2rc6FADFerredoxin--NADP reductase/0.502
3crzFADFerredoxin--NADP+ reductase/0.502
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.500
3zbtFADFerredoxin--NADP reductase1.18.1.20.500
1bjkFADFerredoxin--NADP reductase1.18.1.20.499
1amoFADNADPH--cytochrome P450 reductase/0.498
4bb3KKAIsopenicillin N synthase1.21.3.10.495
1e64FADFerredoxin--NADP reductase1.18.1.20.494
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.493
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.493
1h85FADFerredoxin--NADP reductase1.18.1.20.491
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.491
2abbFMNPentaerythritol tetranitrate reductase/0.491
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.490
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.490
3qftFADNADPH--cytochrome P450 reductase/0.488
1go2FADFerredoxin--NADP reductase1.18.1.20.485
2gvdFKPAdenylate cyclase type 2/0.485
2gvdFKPAdenylate cyclase type 5/0.485
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.485
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.485
4b4dFADFerredoxin-NADP reductase/0.483
4j75TYMTryptophan--tRNA ligase/0.483
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.481
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.481
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.481
3zc3FADFerredoxin--NADP reductase1.18.1.20.481
1szgFNSCytochrome b2, mitochondrial1.1.2.30.480
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
1sq5ADPPantothenate kinase2.7.1.330.478
1x1cSAHC-20 methyltransferase/0.478
4e2dFMNDehydrogenase/0.478
1i0sFMNFerric-chelate reductase (NAD(P)H)/0.477
2qdxFADFerredoxin--NADP+ reductase/0.477
1cnfFADNitrate reductase [NADH]1.7.1.10.475
1cqxFADFlavohemoprotein/0.475
1qgyFADFerredoxin--NADP reductase1.18.1.20.475
3atyFMNProstaglandin F2a synthase/0.475
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.474
4c43FADFerredoxin--NADP reductase1.18.1.20.474
2abaSTRPentaerythritol tetranitrate reductase/0.473
3ojxFMNNADPH--cytochrome P450 reductase/0.473
2vkeTACTetracycline repressor protein class D/0.471
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.470
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.470
4e2xTYDMethyltransferase/0.470
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.469
1bwsNDPGDP-L-fucose synthase/0.468
1jkx138Phosphoribosylglycinamide formyltransferase/0.468
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.468
3bi6396Wee1-like protein kinase2.7.10.20.468
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.468
1udaUFGUDP-glucose 4-epimerase5.1.3.20.467
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.466
4yaoFADNADPH--cytochrome P450 reductase/0.466
2qimZEAClass 10 plant pathogenesis-related protein/0.465
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.465
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.465
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.464
3e6eDCSAlanine racemase/0.464
3p62FMNPentaerythritol tetranitrate reductase/0.464
5ah5LSSLeucine--tRNA ligase/0.464
1gadNADGlyceraldehyde-3-phosphate dehydrogenase A/0.463
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.463
3k8q22APurine nucleoside phosphorylase2.4.2.10.463
4jicFMNGTN Reductase/0.463
1me6IVSPlasmepsin-23.4.23.390.462
1ra3NAPDihydrofolate reductase1.5.1.30.462
2g8yNADHydroxycarboxylate dehydrogenase B/0.462
2xh9J01Uncharacterized protein/0.462
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.462
1ddsMTXDihydrofolate reductase1.5.1.30.461
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3rh7FMNUncharacterized protein/0.461
4du82P0Mevalonate diphosphate decarboxylase/0.461
4v2gITCTetracycline repressor protein class D/0.461
1b2rFADFerredoxin--NADP reductase1.18.1.20.460
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.460
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.460
1ypkCCRProthrombin3.4.21.50.460
2ci01CMLanosterol 14-alpha demethylase1.14.13.700.460
2gtbAZPOrf1ab polyprotein/0.460
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.460
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3tjlFMNNADPH dehydrogenase/0.460
1xelUPGUDP-glucose 4-epimerase5.1.3.20.459
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.459
3b1dPLSBetaC-S lyase/0.459
4a81DXCMajor pollen allergen Bet v 1-A/0.459
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1rx8NAPDihydrofolate reductase1.5.1.30.458
2anb5GPGuanylate kinase2.7.4.80.458
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.458
2pswCOAN-alpha-acetyltransferase 50/0.458
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.458
3bgxMEFThymidylate synthase/0.458
3pmy41LEndothiapepsin3.4.23.220.458
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.458
4k8s1QTBeta-secretase 13.4.23.460.458
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.458
4djhJDCKappa-type opioid receptor/0.458
1cjtFOKAdenylate cyclase type 2/0.457
1cjtFOKAdenylate cyclase type 5/0.457
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.457
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.457
2r26CMCCitrate synthase2.3.3.160.457
3bnkFMNFlavoredoxin/0.457
3gqvNAPEnoyl reductase LovC10.457
3h7rNAPAldo-keto reductase family 4 member C8/0.457
3zpqXF5Beta-1 adrenergic receptor/0.457
4k1xFADNADPH:ferredoxin reductase/0.457
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.457
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.457
1dhfFOLDihydrofolate reductase1.5.1.30.456
1drfFOLDihydrofolate reductase1.5.1.30.456
1gveNAPAflatoxin B1 aldehyde reductase member 310.456
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3f63GTXGlutathione transferase GST1-4/0.456
3h06VBPGlutamate receptor 2/0.456
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.456
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.456
3tfyCOAN-alpha-acetyltransferase 502.3.10.456
3v2uATPProtein GAL3/0.456
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.456
4jtqNAPAldo-keto reductase family 1 member C2/0.456
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.455
2wzySQXSoluble acetylcholine receptor/0.455
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.455
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.455
3rpeFADPutative modulator of drug activity/0.455
4b4w9L9Bifunctional protein FolD/0.455
4bfvZVVPantothenate kinase2.7.1.330.455
4bfzZVZPantothenate kinase2.7.1.330.455
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.454
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.454
3e8xNAPBH1520 protein/0.454
3h2sNDPPutative NADH-flavin reductase/0.454
1disBDMDihydrofolate reductase1.5.1.30.453
1f8fNADBenzyl alcohol dehydrogenase/0.453
1g28FMNPHY3/0.453
1mvsDTMDihydrofolate reductase1.5.1.30.453
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.453
2a5kAZPReplicase polyprotein 1ab3.4.220.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.453
2wtkANPSTE20-related kinase adapter protein alpha/0.453
2zvcSAHPrecorrin-3 C17-methyltransferase/0.453
3a3gDLZLumazine protein/0.453
3hlwCE3Beta-lactamase/0.453
4g95OAGDihydrofolate reductase1.5.1.30.453
4q71FADBifunctional protein PutA/0.453
4y7cFADNADPH--cytochrome P450 reductase/0.453
1h51FMNPentaerythritol tetranitrate reductase/0.452
1jdtMTAPurine nucleoside phosphorylase/0.452
1rneC60Renin3.4.23.150.452
2g1n1IGRenin3.4.23.150.452
2g247IGRenin3.4.23.150.452
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.452
2wzmNA7Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346/0.452
2x9dITCTetracycline repressor protein class D/0.452
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.452
3ag6PAJPantothenate synthetase/0.452
3ihkTPPUncharacterized protein/0.452
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.452
4gxs0YSGlutamate receptor 2/0.452
1bwlFMNNADPH dehydrogenase 11.6.99.10.451
1j9zFADNADPH--cytochrome P450 reductase/0.451
1pd9CO4Dihydrofolate reductase1.5.1.30.451
1pq944BOxysterols receptor LXR-beta/0.451
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.451
1x2hLPALipoate-protein ligase A6.3.1.200.451
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.451
2hfuMEVMevalonate kinase/0.451
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.451
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.451
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.451
4fpy0V8Sialidase B3.2.1.180.451
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
1ay0TPPTransketolase 12.2.1.10.450
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.450
1qrpHH0Pepsin A-43.4.23.10.450
1w6hTITPlasmepsin-23.4.23.390.450
2ctsCOACitrate synthase, mitochondrial2.3.3.10.450
2ed3SAHDiphthine synthase/0.450
2r8oT5XTransketolase 1/0.450
2x06NADL-sulfolactate dehydrogenase/0.450
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.450
3nl6TPSUncharacterized protein/0.450
3p84FMNPentaerythritol tetranitrate reductase/0.450
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4j0v1H7Beta-secretase 13.4.23.460.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1ivsVAAValine--tRNA ligase6.1.1.90.449
1yzqGNPRas-related protein Rab-6A/0.449
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.449
2emrSAHDiphthine synthase/0.449
2gilGTPRas-related protein Rab-6A/0.449
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2owfSAHDiphthine synthase/0.449
2xtnGTPGTPase IMAP family member 2/0.449
3d84NDPDihydrofolate reductase1.5.1.30.449
3mauEXTPutative sphingosine-1-phosphate lyase/0.449
3phjDHKShikimate dehydrogenase (NADP(+))/0.449
4a83DXCMajor pollen allergen Bet v 1-A/0.449
4b4vL34Bifunctional protein FolD/0.449
4i6gFADCryptochrome-2/0.449
4i8vBHFCytochrome P450 1A11.14.14.10.449
5fd8A5APutative carboxypeptidase yocD/0.449
1drhNAPDihydrofolate reductase1.5.1.30.448
1hb1OCVIsopenicillin N synthase1.21.3.10.448
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.448
1w34FADFerredoxin--NADP reductase1.18.1.20.448
2e07SAHDiphthine synthase/0.448
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.448
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.448
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.448
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.448
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.448
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3gfdFMNIodotyrosine deiodinase 11.21.1.10.448
3jv7NADSecondary alcohol dehydrogenase/0.448
3n0hTOPDihydrofolate reductase1.5.1.30.448
3pftFMNFlavin reductase/0.448
3qgf46FGenome polyprotein2.7.7.480.448
3s3vTOPDihydrofolate reductase1.5.1.30.448
3t0iSAHPutative methyltransferase/0.448
4a802ANMajor pollen allergen Bet v 1-A/0.448
4df2FMNNADPH dehydrogenase/0.448
4g67SAHUncharacterized ACR, COG1565 superfamily/0.448
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.448
2y0468HBeta-1 adrenergic receptor/0.448
1a59COA2-methylcitrate synthase/0.447
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1gaxVAAValine--tRNA ligase6.1.1.90.447
1ozpACOMycothiol acetyltransferase2.3.1.1890.447
1qoqIGPTryptophan synthase alpha chain/0.447
1rf7DHFDihydrofolate reductase1.5.1.30.447
2aouCQAHistamine N-methyltransferase2.1.1.80.447
2cndFADNitrate reductase [NADH]1.7.1.10.447
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.447
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.447
2q9fC3SCholesterol 24-hydroxylase/0.447
3atzFMNProstaglandin F2a synthase/0.447
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.447
3tr05GPGuanylate kinase/0.447
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.447
4bftZVTPantothenate kinase2.7.1.330.447
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.447
4ke11R6Beta-secretase 13.4.23.460.447
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.447
1icsFMN12-oxophytodienoate reductase 11.3.1.420.446
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.446
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.446
2fe4GDPRas-related protein Rab-6B/0.446
2igoFADPyranose 2-oxidase/0.446
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2qlnF59Glycogen phosphorylase, muscle form2.4.1.10.446
3k7mFAD6-hydroxy-L-nicotine oxidase/0.446
3nd6ATPPhosphopantetheine adenylyltransferase/0.446
3ou2SAHSAM-dependent methyltransferase/0.446
3qto10PProthrombin3.4.21.50.446
3sxjSAMPutative methyltransferase/0.446
3vyeVYERenin3.4.23.150.446
3zkyWT4Isopenicillin N synthase1.21.3.10.446
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.446
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.446
1h61PDNPentaerythritol tetranitrate reductase/0.445
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.445
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.445
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.445
1sm4FADFerredoxin--NADP reductase/0.445
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2vyqFADFerredoxin--NADP reductase1.18.1.20.445
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.445
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.445
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.445
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
3nxxNDPDihydrofolate reductase1.5.1.30.445
3phiNDPShikimate dehydrogenase (NADP(+))/0.445
3zoiM2WIsopenicillin N synthase1.21.3.10.445
4dptAGSMevalonate diphosphate decarboxylase/0.445
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.445
4y9uFADNADPH--cytochrome P450 reductase/0.445
1gw2FERPeroxidase C1A1.11.1.70.444
1u1gBBBUridine phosphorylase2.4.2.30.444
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.444
2eniSAHDiphthine synthase/0.444
2il2LIXRenin3.4.23.150.444
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.444
3af1GDPPantothenate kinase2.7.1.330.444
3f03FMNPentaerythritol tetranitrate reductase/0.444
3f3sNADLambda-crystallin homolog/0.444
3i0pNADMalate dehydrogenase, putative/0.444
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
4dz5NAPAldo-keto reductase family 1 member C3/0.444
4koaNDP1,5-anhydro-D-fructose reductase1.1.1.2920.444
4r1lADPPhenylacetate-coenzyme A ligase/0.444
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.444
5d5aCAUBeta-2 adrenergic receptor/0.444
1diuBDMDihydrofolate reductase1.5.1.30.443
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.443
1o9bNAIQuinate/shikimate dehydrogenase/0.443
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1v35NAIEnoyl-ACP reductase/0.443
1x8lOXRRetinol dehydratase/0.443
2ejvNADL-threonine 3-dehydrogenase/0.443
2emuSAHDiphthine synthase/0.443
2gevCOKPantothenate kinase2.7.1.330.443
2xlpFADPutative flavin-containing monooxygenase/0.443
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.443
3d91REMRenin3.4.23.150.443
3widNAPGlucose 1-dehydrogenase/0.443
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.443
4xbjIN5Alanine racemase, biosynthetic/0.443
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.442
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.442
1bzfTMQDihydrofolate reductase1.5.1.30.442
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1kvkATPMevalonate kinase2.7.1.360.442
1mvtDTMDihydrofolate reductase1.5.1.30.442
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.442
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.442
1t4u81AProthrombin3.4.21.50.442
1tj0FADBifunctional protein PutA1.5.5.20.442
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.442
1ykdCMPAdenylate cyclase/0.442
2c12FADNitroalkane oxidase1.7.3.10.442
2dsgSAHDiphthine synthase/0.442
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
2he5NDPAldo-keto reductase family 1 member C211.1.10.442
2vj6VG5Beta-secretase 13.4.23.460.442
2ylrNAPPhenylacetone monooxygenase1.14.13.920.442
2zvbSAHPrecorrin-3 C17-methyltransferase/0.442
3bgxTMPThymidylate synthase/0.442
3daaPDDD-alanine aminotransferase2.6.1.210.442
3juqAJDPhenazine biosynthesis protein A/B/0.442
3opxU5PSuppressor of disruption of TFIIS/0.442
3qbjNXZDipeptidyl peptidase 4/0.442
3w8eNAD3-hydroxybutyrate dehydrogenase/0.442
4b68NAPL-ornithine N(5)-monooxygenase/0.442
4emtC2EStimulator of interferon genes protein/0.442
1j4jACOAcetyltransferase2.3.10.441
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.441
1udbUFGUDP-glucose 4-epimerase5.1.3.20.441
2a94AP0L-lactate dehydrogenase1.1.1.270.441
2g1r3IGRenin3.4.23.150.441
2g9rG27Glycogen phosphorylase, muscle form2.4.1.10.441
2gpjFADSiderophore-interacting protein/0.441
2j2pSC2Ficolin-2/0.441
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.441
2wd8VGFPteridine reductase/0.441
2zhq27UProthrombin3.4.21.50.441
2znq401Peroxisome proliferator-activated receptor delta/0.441
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.441
3kybFADUDP-galactopyranose mutase5.4.99.90.441
3tozNADShikimate dehydrogenase (NADP(+))/0.441
3ziuLSSLeucyl-tRNA synthetase/0.441
4ddhMS0Pantothenate synthetase6.3.2.10.441
4l4eCAMCamphor 5-monooxygenase1.14.15.10.441
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.441
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.441
4uugPXGBranched-chain amino acid aminotransferase, putative/0.441
5a3bAPRSIR2 family protein/0.441
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.440
1dhrNADDihydropteridine reductase1.5.1.340.440
1dyjDDFDihydrofolate reductase1.5.1.30.440
1fdoMGDFormate dehydrogenase H1.1.99.330.440
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.440
1u71MXADihydrofolate reductase1.5.1.30.440
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.440
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2djlFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.440
2fj1CTCTetracycline repressor protein class D/0.440
2hxzH7JCathepsin S3.4.22.270.440
2xveFADPutative flavin-containing monooxygenase/0.440
3c27DKKProthrombin3.4.21.50.440
3ixk929Beta-secretase 13.4.23.460.440
3lpiZ74Beta-secretase 13.4.23.460.440
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.440
3vy2FMNFMN-binding protein/0.440
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.440
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.440
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.440
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4fryNADPutative signal-transduction protein with CBS domains/0.440
4fse0VABeta-secretase 13.4.23.460.440
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.440
4xo7NAPAldo-keto reductase family 1 member C2/0.440
4zj8SUVOrexin receptor type 1/0.440