sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fby | REA | Retinoic acid receptor RXR-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 1.000 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.645 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.638 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.636 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.616 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.615 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.613 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.607 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.606 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.601 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.599 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.598 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.597 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.592 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.591 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.591 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.587 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.585 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.585 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.576 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.574 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.555 | |
| 2p15 | EZT | Estrogen receptor | / | 0.518 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 2bxq | IMN | Serum albumin | / | 0.498 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.494 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.494 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.489 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.486 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.484 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 3eek | 53S | Uncharacterized protein | / | 0.481 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.481 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.480 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.479 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.479 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.479 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.479 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.478 | |
| 4apu | A2K | Progesterone receptor | / | 0.478 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.477 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.477 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.476 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.476 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.476 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.475 | |
| 2bxm | IMN | Serum albumin | / | 0.474 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.474 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.474 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.474 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.474 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.473 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.473 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.471 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.471 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.471 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.471 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.471 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.471 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.471 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 2acw | UPG | Glycosyltransferase | / | 0.470 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.470 | |
| 3h18 | PMS | Esterase/lipase | / | 0.470 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.470 | |
| 1ysx | 4EB | Serum albumin | / | 0.469 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.469 | |
| 2xvv | 9DN | Serum albumin | / | 0.469 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.469 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.469 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.469 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.469 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.469 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.468 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.468 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.468 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3eej | 53R | Uncharacterized protein | / | 0.468 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.467 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.466 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2xvw | 9NR | Serum albumin | / | 0.466 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3qly | 55V | Uncharacterized protein | / | 0.466 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.466 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.466 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.466 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.465 | |
| 2pnu | ENM | Androgen receptor | / | 0.465 | |
| 4iah | 1DX | Alr2278 protein | / | 0.465 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.465 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.465 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1osv | CHC | Bile acid receptor | / | 0.464 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.464 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.464 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.464 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.463 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.463 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.462 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.462 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.462 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.462 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.462 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.462 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.462 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.461 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.461 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3b9l | AZZ | Serum albumin | / | 0.461 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.461 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.461 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.461 | |
| 4bmp | FMN | Protein NrdI | / | 0.461 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.460 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.460 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.460 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.459 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.459 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.459 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.459 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.459 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.459 | |
| 4l8u | 9AZ | Serum albumin | / | 0.459 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.458 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 3d90 | NOG | Progesterone receptor | / | 0.458 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.458 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.458 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.458 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.458 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.457 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.457 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.457 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.457 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.457 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.456 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.456 | |
| 3eel | 53T | Uncharacterized protein | / | 0.456 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.456 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.456 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.456 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ezv | SMA | Cytochrome b | / | 0.455 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.455 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.455 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.455 | |
| 3cxh | SMA | Cytochrome b | / | 0.455 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.455 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.454 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.454 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.454 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.454 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.454 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.454 | |
| 4ok1 | 198 | Androgen receptor | / | 0.454 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.454 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.453 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1tz8 | DES | Transthyretin | / | 0.453 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3dol | GWI | Pol protein | / | 0.453 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.453 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.453 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.453 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.453 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.453 | |
| 1fml | RTL | Retinol dehydratase | / | 0.452 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 2ybo | SAH | Methyltransferase | / | 0.452 | |
| 3cse | N22 | Uncharacterized protein | / | 0.452 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.452 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.452 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 1kb9 | SMA | Cytochrome b | / | 0.451 | |
| 1sqv | UHD | Cytochrome b | / | 0.451 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.451 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.451 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.451 | |
| 4egn | TWO | Cytochrome P450 | / | 0.451 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.451 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.451 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.450 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 2mm3 | CHO | Gastrotropin | / | 0.450 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.450 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.450 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.449 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.449 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.449 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.449 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.449 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.449 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.449 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.449 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.449 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1sqq | OST | Cytochrome b | / | 0.448 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.448 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2iog | IOG | Estrogen receptor | / | 0.448 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.448 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.448 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.448 | |
| 3p9t | TCL | Repressor | / | 0.448 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.448 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.448 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.448 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4okx | 198 | Androgen receptor | / | 0.448 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.448 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.448 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.447 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.447 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1err | RAL | Estrogen receptor | / | 0.446 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.446 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.446 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.446 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.446 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.446 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.445 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.445 | |
| 2bxo | OPB | Serum albumin | / | 0.445 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.445 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.445 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.445 | |
| 3l71 | AZO | Cytochrome b | / | 0.445 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.445 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 4okb | 198 | Androgen receptor | / | 0.445 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.444 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.444 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.444 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.444 | |
| 1xpc | AIT | Estrogen receptor | / | 0.444 | |
| 2ay8 | 4TB | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.444 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.444 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.444 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.444 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.444 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.444 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.444 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.444 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4okt | 198 | Androgen receptor | / | 0.444 | |
| 1l0l | FMX | Cytochrome b | / | 0.443 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.443 | |
| 1pp9 | SMA | Cytochrome b | / | 0.443 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.443 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.443 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.443 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.443 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.443 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.443 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.443 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.443 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.443 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1nde | MON | Estrogen receptor beta | / | 0.442 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.442 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.442 | |
| 1sqp | MYX | Cytochrome b | / | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.442 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2jfa | RAL | Estrogen receptor | / | 0.442 | |
| 2jfz | 003 | Glutamate racemase | / | 0.442 | |
| 2uzh | IPE | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.442 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.442 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.442 | |
| 3lu7 | IPX | Serum albumin | / | 0.442 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.442 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.442 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.442 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.442 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.442 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.442 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.442 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.441 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 1ppj | SMA | Cytochrome b | / | 0.441 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.441 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2fai | 459 | Estrogen receptor | / | 0.441 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.441 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3cx5 | SMA | Cytochrome b | / | 0.441 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.441 | |
| 3zux | TCH | Transporter | / | 0.441 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.441 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.441 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.441 | |
| 4l9q | 9TP | Serum albumin | / | 0.441 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.441 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.441 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.440 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.440 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.440 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.440 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.440 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.440 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.440 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.440 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.440 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.440 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.440 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.440 |