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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1el3I84Aldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1el3I84Aldose reductase1.1.1.211.000
2pdkSBIAldose reductase1.1.1.210.743
2iqdLPAAldose reductase1.1.1.210.702
2duxZSTAldose reductase1.1.1.210.699
3m64393Aldose reductase1.1.1.210.696
3lz5LDTAldose reductase1.1.1.210.693
1x96NAPAldose reductase1.1.1.210.683
2iq0NAPAldose reductase1.1.1.210.681
3ghrLDTAldose reductase1.1.1.210.671
2ikj393Aldose reductase1.1.1.210.668
2hvoZSTAldose reductase1.1.1.210.664
4yu153NAldose reductase1.1.1.210.659
3lboLDTAldose reductase1.1.1.210.655
2duzZSTAldose reductase1.1.1.210.653
3ghsLDTAldose reductase1.1.1.210.650
3m4h388Aldose reductase1.1.1.210.650
2dv0ZSTAldose reductase1.1.1.210.649
1ekoI84Aldose reductase1.1.1.210.647
2f2kTGGAldose reductase1.1.1.210.647
4gca2X9Aldose reductase1.1.1.210.647
2is72CLAldose reductase1.1.1.210.646
3u2cSUZAldose reductase1.1.1.210.644
2iki388Aldose reductase1.1.1.210.643
2pdxZSTAldose reductase1.1.1.210.640
3ld5LDTAldose reductase1.1.1.210.640
2pdwFIDAldose reductase1.1.1.210.638
3lqlLDTAldose reductase1.1.1.210.634
3v35NTIAldose reductase1.1.1.210.634
1z3n3NAAldose reductase1.1.1.210.633
2i17LDTAldose reductase1.1.1.210.633
2inzOHPAldose reductase1.1.1.210.631
1pwmFIDAldose reductase1.1.1.210.629
2pdg47DAldose reductase1.1.1.210.629
2pdyFIDAldose reductase1.1.1.210.629
4gabFIDAldo-keto reductase family 1 member B101.1.10.629
5liu388Aldo-keto reductase family 1 member B101.1.10.625
1ah0SBIAldose reductase1.1.1.210.619
2nvcITAAldose reductase1.1.1.210.618
3s3gTLTAldose reductase1.1.1.210.616
3mc5393Aldose reductase1.1.1.210.615
1pwlBFIAldose reductase1.1.1.210.614
2pdmZSTAldose reductase1.1.1.210.610
3mb9ZSTAldose reductase1.1.1.210.610
1ef3FIDAldose reductase1.1.1.210.609
2pd9FIDAldose reductase1.1.1.210.609
2pdfZSTAldose reductase1.1.1.210.607
2pdp393Aldose reductase1.1.1.210.607
2pdq47DAldose reductase1.1.1.210.607
2pdh47DAldose reductase1.1.1.210.605
1z8962PAldose reductase1.1.1.210.604
3p2vDOYAldose reductase1.1.1.210.604
2fz9ZSTAldose reductase1.1.1.210.602
1t41ID5Aldose reductase1.1.1.210.601
2ikhLITAldose reductase1.1.1.210.600
2pdj393Aldose reductase1.1.1.210.600
2pdn47DAldose reductase1.1.1.210.600
2pdc393Aldose reductase1.1.1.210.599
2hv5ZSTAldose reductase1.1.1.210.598
3lenZSTAldose reductase1.1.1.210.597
2pf8NDPAldose reductase1.1.1.210.596
2pzn393Aldose reductase1.1.1.210.596
2pdu393Aldose reductase1.1.1.210.595
2fz8ZSTAldose reductase1.1.1.210.592
3ghuLDTAldose reductase1.1.1.210.590
2pd5ZSTAldose reductase1.1.1.210.589
3v36NAPAldose reductase1.1.1.210.588
4ga8SBIAldo-keto reductase family 1 member B101.1.10.588
2i16LDTAldose reductase1.1.1.210.586
2j8tNAPAldose reductase1.1.1.210.582
2pdlTOLAldose reductase1.1.1.210.582
2acuNAPAldose reductase1.1.1.210.581
2agtFIDAldose reductase1.1.1.210.581
3t423T4Aldose reductase1.1.1.210.579
1us0LDTAldose reductase1.1.1.210.574
2pdbZSTAldose reductase1.1.1.210.572
4wevSUZAldo-keto reductase family 1 member B101.1.10.569
2pevNDPAldose reductase1.1.1.210.566
1t40ID5Aldose reductase1.1.1.210.564
2hvnZSTAldose reductase1.1.1.210.564
1ieiZESAldose reductase1.1.1.210.562
2fzdTOLAldose reductase1.1.1.210.557
3g5eQ74Aldose reductase1.1.1.210.555
2fzbTOLAldose reductase1.1.1.210.550
2qxwLDTAldose reductase1.1.1.210.549
1ah3TOLAldose reductase1.1.1.210.541
2ipw2CLAldose reductase1.1.1.210.540
2nvdITBAldose reductase1.1.1.210.539
1frbZSTAldose reductase-related protein 2/0.536
4stdBFSScytalone dehydratase4.2.1.940.533
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.527
2pfhNDPAldose reductase1.1.1.210.524
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.20.523
5cxv0HKMuscarinic acetylcholine receptor M1/0.523
2bd0BIOSepiapterin reductase/0.522
2pb1NFGGlucan 1,3-beta-glucosidase/0.522
1az1ALRAldose reductase1.1.1.210.516
1zq5E04Aldo-keto reductase family 1 member C3/0.516
5dsg0HKMuscarinic acetylcholine receptor M4/0.516
4kn0MTXFolate receptor beta/0.515
2q94A04Methionine aminopeptidase/0.514
1kmsLIHDihydrofolate reductase1.5.1.30.511
4fa30SLAldo-keto reductase family 1 member C3/0.509
4i5xFLFAldo-keto reductase family 1 member B101.1.10.509
4xo7ASDAldo-keto reductase family 1 member C2/0.509
4daj0HKMuscarinic acetylcholine receptor M3/0.509
1u08PLPMethionine aminotransferase/0.507
2bjsACVIsopenicillin N synthase1.21.3.10.507
4u163C0Muscarinic acetylcholine receptor M3/0.506
2gg3U13Methionine aminopeptidase/0.503
3ug8IMNAldo-keto reductase family 1 member C3/0.503
5stdUNNScytalone dehydratase4.2.1.940.502
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.501
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.500
3stdMQ0Scytalone dehydratase4.2.1.940.500
1ry0PG2Aldo-keto reductase family 1 member C3/0.499
2f3815MAldo-keto reductase family 1 member C3/0.499
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.499
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.498
1s36CEIObelin/0.498
1el4CTZObelin/0.497
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.496
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.496
4hmn16JAldo-keto reductase family 1 member C3/0.496
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.495
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.495
1e6zNGOChitinase/0.494
4jtrIZPAldo-keto reductase family 1 member C2/0.494
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.493
1rxjBNIStreptavidin/0.493
4jtrIBPAldo-keto reductase family 1 member C2/0.493
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.492
2q92B23Methionine aminopeptidase/0.492
3r7mSUZAldo-keto reductase family 1 member C3/0.492
2gg8U15Methionine aminopeptidase/0.491
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.491
2gg0U11Methionine aminopeptidase/0.490
2ipjFFAAldo-keto reductase family 1 member C2/0.490
4da50H7Choline kinase alpha2.7.1.320.490
4kn2LYAFolate receptor beta/0.490
1p0pBCHCholinesterase3.1.1.80.489
2qryTPSThiamine-binding periplasmic protein/0.489
3cv6HXSAldo-keto reductase family 1 member C21/0.489
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
1zuaTOLAldo-keto reductase family 1 member B101.1.10.488
2cekN8TAcetylcholinesterase3.1.1.70.488
2xujTZ5Acetylcholinesterase3.1.1.70.488
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.488
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.488
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.487
3r8hZOMAldo-keto reductase family 1 member C3/0.487
1x2bSTXProline iminopeptidase3.4.11.50.486
4jq4IMNAldo-keto reductase family 1 member C2/0.486
1blzACVIsopenicillin N synthase1.21.3.10.485
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.485
1sjwNGVNogalonic acid methyl ester cyclase/0.485
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.485
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.485
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.485
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.484
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.484
1swtBTNStreptavidin/0.484
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.484
3gyf51PDihydrofolate reductase1.5.1.30.484
3w5uFADFerredoxin/0.484
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.484
2w3mFOLDihydrofolate reductase1.5.1.30.483
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.483
4cb629RPolymerase basic protein 2/0.483
4dbw511Aldo-keto reductase family 1 member C3/0.483
4psbGA3Cytokinin-specific binding protein/0.483
2jl1NAPTriphenylmethane reductase/0.482
2qw8NAPEugenol synthase 11.1.1.3180.482
3d27W29Methionine aminopeptidase/0.482
3iu8T03Methionine aminopeptidase 2/0.482
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.481
1dx6GNTAcetylcholinesterase3.1.1.70.481
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.481
1w6jR71Lanosterol synthase5.4.99.70.481
2g7yMO9Cathepsin S3.4.22.270.481
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.481
3l3rOAGDihydrofolate reductase1.5.1.30.481
4kn104JFolate receptor beta/0.481
1ihiIU5Aldo-keto reductase family 1 member C2/0.480
2vt4P32Beta-1 adrenergic receptor/0.480
2w6cBM4Acetylcholinesterase3.1.1.70.480
3e4vFMNUncharacterized protein/0.480
3zkyWT4Isopenicillin N synthase1.21.3.10.480
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.479
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.479
2evcFC3Methionine aminopeptidase/0.479
2vvlFADMonoamine oxidase N1.4.3.40.479
2z2w770Wee1-like protein kinase2.7.10.20.479
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.479
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.479
1rpwDIDHTH-type transcriptional regulator QacR/0.478
1xf0ASDAldo-keto reductase family 1 member C3/0.478
4dbuBT9Aldo-keto reductase family 1 member C3/0.478
4dz5NAPAldo-keto reductase family 1 member C3/0.478
4xczT3QQdtf/0.478
5cc9DDFDihydrofolate reductase1.5.1.30.478
1lelBH7Avidin/0.477
2evmFC2Methionine aminopeptidase/0.477
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.477
3ugrIMNAldo-keto reductase family 1 member C3/0.477
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.477
4fal0T0Aldo-keto reductase family 1 member C3/0.477
4jtqFLPAldo-keto reductase family 1 member C2/0.477
4to6TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.477
1ohjCOPDihydrofolate reductase1.5.1.30.476
1x2eATXProline iminopeptidase3.4.11.50.476
2gg9U16Methionine aminopeptidase/0.476
2zozETTranscriptional regulator/0.476
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.476
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.476
4jq2SUZAldo-keto reductase family 1 member C2/0.476
4kmzFOLFolate receptor beta/0.476
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.475
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.475
2hzqSTRApolipoprotein D/0.475
3b9gIMHIAG-nucleoside hydrolase/0.475
3jq7DX2Pteridine reductase, putative/0.475
3lzzGDPUncharacterized protein/0.475
3ocw3AMLipoprotein E/0.475
3r6iJMSAldo-keto reductase family 1 member C3/0.475
4j7gTRHPCZA361.3/0.475
1lkeDOGBilin-binding protein/0.474
1zgcA2EAcetylcholinesterase3.1.1.70.474
2avxHTFRegulatory protein SdiA/0.474
2hxzH7JCathepsin S3.4.22.270.474
2q93B21Methionine aminopeptidase/0.474
3r58NPSAldo-keto reductase family 1 member C3/0.474
1jf0CZHObelin/0.473
1u65CP0Acetylcholinesterase3.1.1.70.473
2e82IM3D-amino-acid oxidase1.4.3.30.473
2f59INI6,7-dimethyl-8-ribityllumazine synthase 1/0.473
2pucGUNHTH-type transcriptional repressor PurR/0.473
2yg5FADPutrescine oxidase/0.473
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.473
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.473
1dlsMTXDihydrofolate reductase1.5.1.30.472
1qtiGNTAcetylcholinesterase3.1.1.70.472
1sm4FADFerredoxin--NADP reductase/0.472
1t7o152Carnitine O-acetyltransferase2.3.1.70.472
1zgbA1EAcetylcholinesterase3.1.1.70.472
2gyuHI6Acetylcholinesterase3.1.1.70.472
3b9lAZZSerum albumin/0.472
3qftFADNADPH--cytochrome P450 reductase/0.472
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.472
3u8dU8DPhospholipase A2, membrane associated/0.472
3voiRCBGlucanase/0.472
4n9qFMNFMN-dependent NADH-azoreductase 1/0.472
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.472
1i05LTLMajor urinary protein 6/0.471
1pj6FOLDimethylglycine oxidase1.5.3.100.471
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.471
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.471
3owxXRARibosyldihydronicotinamide dehydrogenase [quinone]/0.471
4arbC57Acetylcholinesterase3.1.1.70.471
4bfuZVUPantothenate kinase2.7.1.330.471
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.470
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.470
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
2gl0ADNUncharacterized protein/0.470
2oadGTBGlutathione S-transferase P 12.5.1.180.470
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.470
2q96A18Methionine aminopeptidase/0.470
3iu7FCDMethionine aminopeptidase 2/0.470
3nwlNDPCatalase1.11.1.60.470
3r8gIZPAldo-keto reductase family 1 member C3/0.470
4dlcUMPDeoxyuridine triphosphatase, putative/0.470
4fam0SZAldo-keto reductase family 1 member C3/0.470
4m6kFOLDihydrofolate reductase1.5.1.30.470
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.469
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
2cjeDUNDUTPase/0.469
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.469
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.469
3f3y4OABile salt sulfotransferase2.8.2.140.469
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.469
3zoiM2WIsopenicillin N synthase1.21.3.10.469
4cb593GPolymerase basic protein 2/0.469
4kbn25UDihydrofolate reductase1.5.1.30.469
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.468
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
1obnASVIsopenicillin N synthase1.21.3.10.468
2a5c8DAAvidin/0.468
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.468
2vq3NAPMetalloreductase STEAP3/0.468
3af3GCPPantothenate kinase2.7.1.330.468
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.468
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.468
3r43ID8Aldo-keto reductase family 1 member C3/0.468
4b7zQ4QAcetylcholinesterase3.1.1.70.468
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.468
4hyf1AKTankyrase-22.4.2.300.468
4jq1NPSAldo-keto reductase family 1 member C2/0.468
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.468
4qtnNNRNicotinamide riboside transporter PnuC/0.468
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.467
1lnmDTXBilin-binding protein/0.467
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.467
2x9vTMQPteridine reductase/0.467
2xuhTZ4Acetylcholinesterase3.1.1.70.467
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
3pkeY10Methionine aminopeptidase 2/0.467
4h7c10HAldo-keto reductase family 1 member C3/0.467
4n3l2FNProthrombin3.4.21.50.467
4ucoIWHDNA ligase/0.467
4zukNADAlpha-aminoadipic semialdehyde dehydrogenase1.2.1.310.467
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.466
1qjfACSIsopenicillin N synthase1.21.3.10.466
1rkwPNTHTH-type transcriptional regulator QacR/0.466
2ea4F79Methionine aminopeptidase 2/0.466
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.466
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.466
3c1oNAPEugenol synthase/0.466
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.466
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.466
3htjETEbrA repressor/0.466
3k31NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
3nxoD2BDihydrofolate reductase1.5.1.30.466
4kfjFOLDihydrofolate reductase1.5.1.30.466
4m0f1YKAcetylcholinesterase3.1.1.70.466
1gjrFADFerredoxin--NADP reductase1.18.1.20.465
1ij8BNIAvidin/0.465
2j3qTFLAcetylcholinesterase3.1.1.70.465
2vrjNCWBeta-glucosidase A3.2.1.210.465
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.465
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.465
3o3rNAPAldose reductase-related protein 11.1.1.210.465
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.465
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.465
4dbs0HVAldo-keto reductase family 1 member C3/0.465
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.465
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
1aqv0HGGlutathione S-transferase P2.5.1.180.464
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
2gs9SAHUncharacterized protein/0.464
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.464
2zseACPPantothenate kinase2.7.1.330.464
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.464
3v94WYQPhosphodiesterase/0.464
4bftZVTPantothenate kinase2.7.1.330.464
4dvi2IWTankyrase-12.4.2.300.464
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region/0.464
4lrhFOLFolate receptor alpha/0.464
4lxb7R9Prothrombin3.4.21.50.464
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
1qv0CZHObelin/0.463
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.463
1vp5NAPOxidoreductase, aldo/keto reductase family/0.463
1w35FADFerredoxin--NADP reductase1.18.1.20.463
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.463
2bd0NAPSepiapterin reductase/0.463
2bu5TF1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.463
2gmvUN8Phosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.463
2w3aTOPDihydrofolate reductase1.5.1.30.463
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3h0vM2TS-adenosylmethionine decarboxylase proenzyme4.1.1.500.463
3lg5BTMEpi-isozizaene synthase4.2.3.370.463
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.463
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.463
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.463
4x3uSVRChromobox protein homolog 7/0.463
1enpNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.462
1jf2CZHObelin/0.462
1q83TZ5Acetylcholinesterase3.1.1.70.462
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
1w4lGL8Acetylcholinesterase3.1.1.70.462
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
1yw7A41Methionine aminopeptidase 2/0.462
2gywOBIAcetylcholinesterase3.1.1.70.462
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.462
3nu03TUDihydrofolate reductase1.5.1.30.462
3pkaY02Methionine aminopeptidase 2/0.462
4ey7E20Acetylcholinesterase3.1.1.70.462
4kebFOLDihydrofolate reductase1.5.1.30.462
4mfpCOAUncharacterized protein/0.462
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.462
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.461
1pq6965Oxysterols receptor LXR-beta/0.461
2fzjDH3Dihydrofolate reductase1.5.1.30.461
2stdCRPScytalone dehydratase4.2.1.940.461
2xlpNAPPutative flavin-containing monooxygenase/0.461
2yg3FADPutrescine oxidase/0.461
3af4GCPPantothenate kinase2.7.1.330.461
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3gx9TXDMorphinone reductase/0.461
3nxtD2EDihydrofolate reductase1.5.1.30.461
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.461
3uweVJJAldo-keto reductase family 1 member C3/0.461
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3znqSS8D-amino-acid oxidase1.4.3.30.461
4bjbP34Tankyrase-22.4.2.300.461
4dya0MFNucleoprotein/0.461
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.461
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.461
4u95MIYMultidrug efflux pump subunit AcrB/0.461
1dr4HBIDihydrofolate reductase1.5.1.30.460
1vfsDCSAlanine racemase/0.460
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.460
2hdjNDPAldo-keto reductase family 1 member C2/0.460
2p98YE7Methionine aminopeptidase/0.460
3c0zSHHHistone deacetylase 73.5.1.980.460
3ghvGHCDihydrofolate reductase1.5.1.30.460
3h7rNAPAldo-keto reductase family 4 member C8/0.460
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.460
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3zv7NHGAcetylcholinesterase3.1.1.70.460
4g56SAHProtein arginine N-methyltransferase 5/0.460
4gvsF4MMethenyltetrahydromethanopterin cyclohydrolase3.5.4.270.460
4juiEGRTannase/0.460
4u140HKMuscarinic acetylcholine receptor M3/0.460
1acjTHAAcetylcholinesterase3.1.1.70.459
1s7gNADNAD-dependent protein deacylase 2/0.459
1w87FADFerredoxin--NADP reductase1.18.1.20.459
1xq04TRCarbonic anhydrase 24.2.1.10.459
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.459
2g263LGRenin3.4.23.150.459
2ggbU17Methionine aminopeptidase/0.459
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2po3T4K4-dehydrase/0.459
2qx7NAPEugenol synthase 11.1.1.3180.459
2vqzMGTPolymerase basic protein 2/0.459
2zsbADPPantothenate kinase2.7.1.330.459
3aezGDPPantothenate kinase2.7.1.330.459
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.459
3h1qATPEthanolamine utilization protein EutJ/0.459
3o76GTBGlutathione S-transferase P 12.5.1.180.459
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.459
4ey6GNTAcetylcholinesterase3.1.1.70.459
4gt8ADPSensor protein VraS2.7.13.30.459
4u150HKMuscarinic acetylcholine receptor M3/0.459
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.458
1h22E10Acetylcholinesterase3.1.1.70.458
1jdzFMBPurine nucleoside phosphorylase/0.458
1lqaNDPProtein tas/0.458
1mrqSTRAldo-keto reductase family 1 member C1/0.458
1pd8CO4Dihydrofolate reductase1.5.1.30.458
1ry8RUTAldo-keto reductase family 1 member C3/0.458
1s1rNAPAldo-keto reductase family 1 member C3/0.458
1uhjCZBAequorin-2/0.458
1w1vALJChitinase/0.458
2cmfF11Acetylcholinesterase3.1.1.70.458
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.458
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3m0iZSTAldose reductase1.1.1.210.458
3nxrD2DDihydrofolate reductase1.5.1.30.458
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.458
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4pnmNU1Tankyrase-22.4.2.300.458
1e62FADFerredoxin--NADP reductase1.18.1.20.457
1ej3CZHAequorin-2/0.457
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
1yw8A75Methionine aminopeptidase 2/0.457
2bf7HBIPteridine reductase 11.5.1.330.457
2io6330Wee1-like protein kinase2.7.10.20.457
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.457
2vbpVB1Isopenicillin N synthase1.21.3.10.457
2xukTZ5Acetylcholinesterase3.1.1.70.457
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.457
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3n3bFMNProtein NrdI/0.457
3ntz3TZDihydrofolate reductase1.5.1.30.457
3u8fFGMRibosome inactivating protein/0.457
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.457
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.457
8catNDPCatalase1.11.1.60.457
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.456
1gt5BZQOdorant-binding protein/0.456
1gw2FERPeroxidase C1A1.11.1.70.456
2bfaCB3Pteridine reductase 11.5.1.330.456
2h7jH7JCathepsin S3.4.22.270.456
2j7cIDEBeta-glucosidase A3.2.1.210.456
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
2p99YE6Methionine aminopeptidase/0.456
2wmdZZ0NmrA-like family domain-containing protein 1/0.456
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.456
3cqeP91Wee1-like protein kinase2.7.10.20.456
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.456
3pkdY10Methionine aminopeptidase 2/0.456
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.456
3zo7K6HMuconolactone Delta-isomerase/0.456
4dyb0MHNucleoprotein/0.456
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
1c23MPHMethionine aminopeptidase/0.455
1eveE20Acetylcholinesterase3.1.1.70.455
1gj4132Prothrombin3.4.21.50.455
2ga2A19Methionine aminopeptidase 2/0.455
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.455
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.455
2x1lADNMethionine--tRNA ligase/0.455
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.455
3gxfIFMGlucosylceramidase3.2.1.450.455
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.455
4a7zAY9Aldos-2-ulose dehydratase/0.455
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.455
4phlPILPhosphodiesterase/0.455
4zasTYDCalS13/0.455
1d3dBZTProthrombin3.4.21.50.454
1dgbNDPCatalase1.11.1.60.454
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.454
1p33MTXPteridine reductase 11.5.1.330.454
1r5gAO1Methionine aminopeptidase 2/0.454
1sl9CZHObelin/0.454
2cn0F25Prothrombin3.4.21.50.454
2xuqTZ4Acetylcholinesterase3.1.1.70.454
3dccD9ZCarbonic anhydrase 24.2.1.10.454
3ptqNFGBeta-glucosidase 12/0.454
3qeoLLTDeoxycytidine kinase2.7.1.740.454
3zc3FADFerredoxin--NADP reductase1.18.1.20.454
4cb4MGTPolymerase basic protein 2/0.454
4jq3ZOMAldo-keto reductase family 1 member C2/0.454
4k4eK4ETankyrase-12.4.2.300.454
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.454
2ckmAA7Acetylcholinesterase3.1.1.70.453
2xufTZ4Acetylcholinesterase3.1.1.70.453
3b9oFMNAlkane monoxygenase/0.453
3cfoGMPDNA-directed DNA polymerase/0.453
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.453
4j7hTRHPCZA361.3/0.453
5fd8A5APutative carboxypeptidase yocD/0.453
5jdzSAHMethyl transferase/0.453
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.452
1o5gCR9Prothrombin3.4.21.50.452
1qvtPRLHTH-type transcriptional regulator QacR/0.452
1w19T4P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1w6rGNTAcetylcholinesterase3.1.1.70.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
1yhoTRRDihydrofolate reductase1.5.1.30.452
2a4xBLMMitomycin-binding protein/0.452
2xugTZ4Acetylcholinesterase3.1.1.70.452
2yg4FADPutrescine oxidase/0.452
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.452
3e9sTTTReplicase polyprotein 1ab3.4.220.452
3gf4U5PUDP-galactopyranose mutase5.4.99.90.452
3up3XCAaceDAF-12/0.452
3znrNU9Histone deacetylase 73.5.1.980.452
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.452
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4h2uATPAmino acid--[acyl-carrier-protein] ligase 16.2.1.n20.452
4ixt1H1Halohydrin dehalogenase/0.452
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
5fljQUEQuercetinase QueD/0.452
1dghNDPCatalase1.11.1.60.451
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.451
1qh0FADFerredoxin--NADP reductase1.18.1.20.451
1r58AO5Methionine aminopeptidase 2/0.451
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2j7dGI1Beta-glucosidase A3.2.1.210.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.451
2r86ATP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.451
2vq7NAPPutative flavin-containing monooxygenase/0.451
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.451
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.451
3hkuTORCarbonic anhydrase 24.2.1.10.451
3irhDTPHD domain protein/0.451
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.451
4bfsZVSPantothenate kinase2.7.1.330.451
4dkbDUNDeoxyuridine triphosphatase, putative/0.451
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4ld2CTNCytidine and deoxycytidylate deaminase zinc-binding region/0.451
4li61XOTankyrase-12.4.2.300.451
4nqgCZHMitrocomin/0.451
4qij1HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.451
1gpnHUBAcetylcholinesterase3.1.1.70.450
1upw444Oxysterols receptor LXR-beta/0.450
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2e40LGCBeta-glucosidase 1A3.2.1.210.450
2pdiZSTAldose reductase1.1.1.210.450
2xupTZ5Acetylcholinesterase3.1.1.70.450
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3vo2FADFerredoxin--NADP reductase/0.450
4boeCLRJapanin/0.450
4l1xSTRAldo-keto reductase family 1 member C2/0.450
4mfqCOAUncharacterized protein/0.450
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.450
4mrxCZHObelin/0.450
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.450
2ycxP32Beta-1 adrenergic receptor/0.450
1dpmEBPParathion hydrolase3.1.8.10.449
1gj5130Prothrombin3.4.21.50.449
1hb1OCVIsopenicillin N synthase1.21.3.10.449
1x8lOXRRetinol dehydratase/0.449
2b1i93ABifunctional purine biosynthesis protein PURH2.1.2.30.449
2b8jADNClass B acid phosphatase3.1.3.20.449
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.449
2onfCOAUncharacterized protein/0.449
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.449
2z7gEH9Adenosine deaminase3.5.4.40.449
3n3aFMNProtein NrdI/0.449
3nn6HNK6-hydroxy-L-nicotine oxidase/0.449
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
3zdnFADMonoamine oxidase N1.4.3.40.449
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.448
1ahbFMPRibosome-inactivating protein momordin I3.2.2.220.448
1h8hADPATP synthase subunit alpha, mitochondrial/0.448
1h8hADPATP synthase subunit beta, mitochondrial3.6.3.140.448
1kmvLIIDihydrofolate reductase1.5.1.30.448
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.448
1p8dCO1Oxysterols receptor LXR-beta/0.448
1rftPXMPyridoxal kinase2.7.1.350.448
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.448
1ycgFMNNitric oxide reductase10.448
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.448
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.448
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2rd2QSIGlutamine--tRNA ligase6.1.1.180.448
2y6fM9FIsopenicillin N synthase1.21.3.10.448
3djfBC3Purine nucleoside phosphorylase/0.448
3dr7GPDGDP-perosamine synthase/0.448
3ghtLDTAldose reductase1.1.1.210.448
3h3t16HCollagen type IV alpha-3-binding protein/0.448
3hthPRLEbrA repressor/0.448
3p2hNOOAcyl-homoserine-lactone synthase/0.448
3p70ILE_PHE_GLU_PRO_PROProthrombin3.4.21.50.448
3qgi33FGenome polyprotein2.7.7.480.448
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.448
3w2eFADNADH-cytochrome b5 reductase 31.6.2.20.448
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.448
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4b66NAPL-ornithine N(5)-monooxygenase/0.448
4bfxZVXPantothenate kinase2.7.1.330.448
4g8cC6LAlpha/beta hydrolase fold protein/0.448
4hlh20DTankyrase-22.4.2.300.448
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.448
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.448
4ure1PSCyclohexanol dehydrogenase/0.448
1e2lTMCThymidine kinase/0.447
1i7cMGBS-adenosylmethionine decarboxylase proenzyme4.1.1.500.447
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.447
1votHUPAcetylcholinesterase3.1.1.70.447
1wm1PTBProline iminopeptidase3.4.11.50.447
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.447
1z71L17Prothrombin3.4.21.50.447
2aj4ANPGalactokinase2.7.1.60.447
2cdaNAPGlucose 1-dehydrogenase/0.447
2gg2U12Methionine aminopeptidase/0.447
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.447
2tohHBITyrosine 3-monooxygenase1.14.16.20.447
2xvw9NRSerum albumin/0.447
3cuiX4SExoglucanase/xylanase3.2.1.910.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3gamMXXRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.447
3n0hTOPDihydrofolate reductase1.5.1.30.447
3ocx2AMLipoprotein E/0.447
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.447
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
3vilSA0Beta-glucosidase/0.447
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.447
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.447
1cjkFOKAdenylate cyclase type 2/0.446
1cjkFOKAdenylate cyclase type 5/0.446
1o6qR17Squalene--hopene cyclase4.2.1.1290.446
1ohkCOPDihydrofolate reductase1.5.1.30.446
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.446
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.446
1qgyFADFerredoxin--NADP reductase1.18.1.20.446
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2ha6SCKAcetylcholinesterase3.1.1.70.446
2nnqT4BFatty acid-binding protein, adipocyte/0.446
2xlrNAPPutative flavin-containing monooxygenase/0.446
2xuoTZ4Acetylcholinesterase3.1.1.70.446
2z4w749Geranylgeranyl pyrophosphate synthase/0.446
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.446
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.446
3juoAJDPhenazine biosynthesis protein A/B/0.446
3ou2SAHSAM-dependent methyltransferase/0.446
3t31DCQSulfide-quinone reductase/0.446
3wznBTNStreptavidin/0.446
3zkuHCVIsopenicillin N synthase1.21.3.10.446
4a16H34Acetylcholinesterase3.1.1.70.446
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.446
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.446
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4fljY08Methionine aminopeptidase 1/0.446
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.446
4iksTFDMethionine aminopeptidase 1/0.446
4isg1FYGlucokinase2.7.1.20.446
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.446
4o7gASCProbable transmembrane ascorbate ferrireductase 21.16.5.10.446
4uugPXGBranched-chain amino acid aminotransferase, putative/0.446
1dp2LPBThiosulfate sulfurtransferase/0.445
1gulGLY_GGL_ICYGlutathione S-transferase A42.5.1.180.445
1ogjFADFerredoxin--NADP reductase1.18.1.20.445
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.445
1pqc444Oxysterols receptor LXR-beta/0.445
1u70MTXDihydrofolate reductase1.5.1.30.445
1ut6A8NAcetylcholinesterase3.1.1.70.445
1w7gMIUProthrombin3.4.21.50.445
1xm1GAHProthrombin3.4.21.50.445
2a8gGNGAvidin/0.445
2aclL05Oxysterols receptor LXR-alpha/0.445
2fyuFDNCytochrome b/0.445
2hejNDPAldo-keto reductase family 1 member C211.1.10.445
2r6kGTXGlutathione S-transferase A12.5.1.180.445
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.445
2vz0D64Pteridine reductase/0.445
2xi4AFTAcetylcholinesterase3.1.1.70.445
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.445
2y4sBCDLimit dextrinase/0.445
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.445
3fsjD7KBenzoylformate decarboxylase4.1.1.70.445
3jq6DX1Pteridine reductase, putative/0.445
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3nxvD2FDihydrofolate reductase1.5.1.30.445
3oikWZBCarbonic anhydrase 24.2.1.10.445
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.445
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.445
3ustFADAcMNPV orf92/0.445
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.445
4b65NDPL-ornithine N(5)-monooxygenase/0.445
4dc1NDPPutative ketoacyl reductase1.3.10.445
4ea2RWZDehydrosqualene synthase/0.445
4flkY10Methionine aminopeptidase 1/0.445
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.445
4jvlESTEstrogen sulfotransferase2.8.2.40.445
4x9dU5PUncharacterized protein MJ1435/0.445
5ewkP34Putative secreted protein/0.445
1dlrMXADihydrofolate reductase1.5.1.30.444
1esmCOAPantothenate kinase2.7.1.330.444
1gky5GPGuanylate kinase2.7.4.80.444
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1h85FADFerredoxin--NADP reductase1.18.1.20.444
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1m2xMCOMetallo-beta-lactamase type 2/0.444
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.444
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.444
1tojHCIAspartate aminotransferase2.6.1.10.444
1u0hFOKAdenylate cyclase type 2/0.444
1u0hFOKAdenylate cyclase type 5/0.444
2alyYSAPhenylalanine--tRNA ligase alpha subunit6.1.1.200.444
2nq7HM5Methionine aminopeptidase 1/0.444
2wo7ASVIsopenicillin N synthase1.21.3.10.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
2z4y252Geranylgeranyl pyrophosphate synthase/0.444
2zevB71Geranylgeranyl pyrophosphate synthase/0.444
3af1GDPPantothenate kinase2.7.1.330.444
3ai0PNWBeta-glucosidase/0.444
3arqDM5Chitinase A/0.444
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3mjrAC2Deoxycytidine kinase2.7.1.740.444
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.444
3ufyNPXAldo-keto reductase family 1 member C3/0.444
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.444
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.444
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.444
4es5MGTPolymerase basic protein 2/0.444
4mv1ADPBiotin carboxylase6.3.4.140.444
4n1fCZHObelin/0.444
4n65FMNFMN-dependent NADH-azoreductase 1/0.444
4nceMGTPolymerase basic protein 2/0.444
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.444
4q0kGA3Phytohormone-binding protein/0.444
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.443
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.443
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.443
2bfmTOPPteridine reductase 11.5.1.330.443
2bu2TF1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.443
2oacGTBGlutathione S-transferase P 12.5.1.180.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
2wm3NFLNmrA-like family domain-containing protein 1/0.443
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.443
2xuiTZ5Acetylcholinesterase3.1.1.70.443
2zbvADNUncharacterized protein/0.443
3af0GDPPantothenate kinase2.7.1.330.443
3dd0EZLCarbonic anhydrase 24.2.1.10.443
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.443
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.443
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.443
3f0aACOSpermidine N(1)-acetyltransferase/0.443
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3n39FMNProtein NrdI/0.443
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.443
3p5lIT5Carbonic anhydrase 24.2.1.10.443
3sfy3FYUncharacterized protein/0.443
3v0o4GWHisto-blood group ABO system transferase/0.443
4bfyZVYPantothenate kinase2.7.1.330.443
4blcNDPCatalase1.11.1.60.443
4bmpFMNProtein NrdI/0.443
4isuIKMGlutamate receptor 2/0.443
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.443
4relKMPGlycosyltransferase/0.443
4xd1T3QQdtf/0.443
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.443
5jqhCAUBeta-2 adrenergic receptor/0.443
1hfrMOTDihydrofolate reductase1.5.1.30.442
1lcwSHMStreptavidin/0.442
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1wopFFOAminomethyltransferase/0.442
2bxmIMNSerum albumin/0.442
2bxqIMNSerum albumin/0.442
2ct8MSPMethionine--tRNA ligase6.1.1.100.442
2dxeGDPNucleoside diphosphate kinase2.7.4.60.442
2gbyBRNHTH-type transcriptional regulator QacR/0.442
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.442
2opxDXCLactaldehyde dehydrogenase1.2.1.220.442
2pksG44Prothrombin3.4.21.50.442
2yayDUPDUTPase/0.442
3gieACPSensor histidine kinase DesK2.7.13.30.442
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4c43FADFerredoxin--NADP reductase1.18.1.20.442
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.442
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.442
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.442
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4l2g1V4Tankyrase-22.4.2.300.442
4l321VFTankyrase-22.4.2.300.442
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.442
4yfy0FXVioF/0.442
1b2rFADFerredoxin--NADP reductase1.18.1.20.441
1fkhSBXPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
1gaqFADFerredoxin/0.441
1gawFADFerredoxin/0.441
1jwtBLIProthrombin3.4.21.50.441
1mvsDTMDihydrofolate reductase1.5.1.30.441
1pj7FFODimethylglycine oxidase1.5.3.100.441
1s2cFLFAldo-keto reductase family 1 member C3/0.441
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2aouCQAHistamine N-methyltransferase2.1.1.80.441
2e41BTX235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase/0.441
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2g6pHM2Methionine aminopeptidase 1/0.441
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
2qjpANJCytochrome b/0.441
2r4uADPGlycogen synthase2.4.1.210.441
2vqbNAPPutative flavin-containing monooxygenase/0.441
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.441
3dz4C8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.441
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.441
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4a7yNHFAldos-2-ulose dehydratase/0.441
4bjcRPBTankyrase-22.4.2.300.441
4dz7D02Carbonic anhydrase 24.2.1.10.441
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.441
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.441
4jqaID8Aldo-keto reductase family 1 member C2/0.441
4jvnYUGEstrogen sulfotransferase2.8.2.40.441
4kak06UDihydrofolate reductase1.5.1.30.441
4kd79DRDihydrofolate reductase1.5.1.30.441
4kxjP34Nucleoprotein/0.441
4m0cFMNFMN-dependent NADH-azoreductase 1/0.441
4to1DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
1a4wQWEProthrombin3.4.21.50.440
1c4yIH3Prothrombin3.4.21.50.440
1dhfFOLDihydrofolate reductase1.5.1.30.440
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.440
1s9dAFBCytohesin-2/0.440
1s9dAFBADP-ribosylation factor 1/0.440
1swgBTNStreptavidin/0.440
1v35NAIEnoyl-ACP reductase/0.440
1xnzFCDMethionine aminopeptidase/0.440
2b82ADNClass B acid phosphatase3.1.3.20.440
2bdyUNBProthrombin3.4.21.50.440
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.440
2c6c24IGlutamate carboxypeptidase 23.4.17.210.440
2d06ESTSulfotransferase 1A12.8.2.10.440
2oazI96Methionine aminopeptidase 2/0.440
2rfiSAHHistone-lysine N-methyltransferase EHMT1/0.440
2v0mKLNCytochrome P450 3A4/0.440
2vqjTFGHistone deacetylase 43.5.1.980.440
2xnvVU3Soluble acetylcholine receptor/0.440
2zs9ADPPantothenate kinase2.7.1.330.440
3c10TSNHistone deacetylase 73.5.1.980.440
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.440
3n9jEAAGlutathione S-transferase P2.5.1.180.440
3q9bB3NAcetylpolyamine amidohydrolase/0.440
3t0kDCQSulfide-quinone reductase/0.440
4bfwZVWPantothenate kinase2.7.1.330.440
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.440
4hxx1AYMethionine aminopeptidase 1/0.440
4j3mAJ8Tankyrase-22.4.2.300.440
4kykIMNLactoylglutathione lyase4.4.1.50.440
4tjy3GNTankyrase-22.4.2.300.440