sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1eko | I84 | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 1.000 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.658 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.651 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.611 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.600 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.594 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.583 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.580 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.570 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.569 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.566 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.559 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.557 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.552 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.551 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.550 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.549 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.548 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.548 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.548 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.543 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.538 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.529 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.527 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.520 | |
| 1x96 | NAP | Aldose reductase | 1.1.1.21 | 0.516 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.516 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.500 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.499 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.497 | |
| 2acu | NAP | Aldose reductase | 1.1.1.21 | 0.496 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.493 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.490 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.485 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.483 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.481 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.481 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2acq | NAP | Aldose reductase | 1.1.1.21 | 0.478 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.477 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.475 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.474 | |
| 3v36 | NAP | Aldose reductase | 1.1.1.21 | 0.474 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.473 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.473 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.473 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.471 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.470 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.469 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.468 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.468 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.467 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.467 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.466 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.466 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.466 | |
| 4kxj | P34 | Nucleoprotein | / | 0.466 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.465 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.465 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.465 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.465 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.464 | |
| 3arz | I5I | Chitinase A | / | 0.464 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.464 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.463 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.463 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.462 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.461 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.461 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.461 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.461 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.460 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.460 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.460 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.458 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.458 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.456 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.456 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.456 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.456 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.456 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.456 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.454 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.453 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 3qen | 5BT | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ejz | SAH | Diphthine synthase | / | 0.451 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.451 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.451 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.451 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.451 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 1s07 | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.450 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.450 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.450 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.449 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.448 | |
| 2bxo | OPB | Serum albumin | / | 0.448 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.448 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.447 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.446 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.446 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1mmv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.445 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.444 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.443 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4ixt | 1H1 | Halohydrin dehalogenase | / | 0.443 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.443 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.442 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.442 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.441 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.441 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.441 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.441 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.440 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.440 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.440 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.440 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 |