scPDB - Distribution of Cavity Similarity values of 1eg2 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1eg2	MTA	Modification methylase RsrI	2.1.1.72

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
1eg2	MTA	Modification methylase RsrI	2.1.1.72	1.000
1nw5	SAM	Modification methylase RsrI	2.1.1.72	0.610
1nw6	SFG	Modification methylase RsrI	2.1.1.72	0.593
3swr	SFG	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.514
3pt9	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.486
4rtp	SAM	DNA adenine methylase	2.1.1.72	0.485
4rtr	SAM	DNA adenine methylase	2.1.1.72	0.475
4rtl	SFG	DNA adenine methylase	2.1.1.72	0.474
4rtn	SAH	DNA adenine methylase	2.1.1.72	0.474
1e8z	STU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.467
2ore	SAH	DNA adenine methylase	2.1.1.72	0.465
2yvl	SAM	tRNA (adenine(58)-N(1))-methyltransferase TrmI	/	0.465
4rts	SAM	DNA adenine methylase	2.1.1.72	0.461
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
2zif	SAM	Methyltransferase	/	0.457
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.456
2dpm	SAM	Modification methylase DpnIIA	2.1.1.72	0.455
2pwy	SAH	tRNA (adenine(58)-N(1))-methyltransferase TrmI	2.1.1.220	0.455
1qyw	5SD	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.454
4rtm	SAM	DNA adenine methylase	2.1.1.72	0.453
4onj	SFG	DNA methyltransferase	/	0.451
4rtj	SFG	DNA adenine methylase	2.1.1.72	0.449
3ua3	SAH	Protein arginine N-methyltransferase 5	/	0.448
3v97	SAH	Ribosomal RNA large subunit methyltransferase K/L	2.1.1.173	0.448
2oeg	UPG	UDP-glucose pyrophosphorylase	/	0.447
3ldf	SAH	Uncharacterized protein	/	0.447
4wxx	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.445
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.443
4rtk	SAH	DNA adenine methylase	2.1.1.72	0.443
4blw	SAH	Ribosomal RNA large subunit methyltransferase J	/	0.442
4rto	SFG	DNA adenine methylase	2.1.1.72	0.441
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.440