Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e92HBIPteridine reductase 11.5.1.33

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1e92HBIPteridine reductase 11.5.1.331.000
2bfpH4BPteridine reductase 11.5.1.330.845
2bf7HBIPteridine reductase 11.5.1.330.691
3h4vDVPPteridine reductase 11.5.1.330.656
2bfaCB3Pteridine reductase 11.5.1.330.617
2qhxFE1Pteridine reductase 11.5.1.330.614
3h4vNAPPteridine reductase 11.5.1.330.597
2bfmTOPPteridine reductase 11.5.1.330.588
1e7wMTXPteridine reductase 11.5.1.330.461
1p33MTXPteridine reductase 11.5.1.330.452
1mxfMTXPutative pteridine reductase 2/0.446
1v7aFRCAdenosine deaminase3.5.4.40.446
2z7gEH9Adenosine deaminase3.5.4.40.444
3cth319Hepatocyte growth factor receptor2.7.10.10.440
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.440