Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e63FADFerredoxin--NADP reductase1.18.1.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1e63FADFerredoxin--NADP reductase1.18.1.21.000
1qgzFADFerredoxin--NADP reductase1.18.1.20.807
1e64FADFerredoxin--NADP reductase1.18.1.20.715
1qgyFADFerredoxin--NADP reductase1.18.1.20.683
1queFADFerredoxin--NADP reductase1.18.1.20.675
1bjkFADFerredoxin--NADP reductase1.18.1.20.674
1qh0FADFerredoxin--NADP reductase1.18.1.20.669
1e62FADFerredoxin--NADP reductase1.18.1.20.650
1h85FADFerredoxin--NADP reductase1.18.1.20.645
4bprFADFerredoxin--NADP reductase1.18.1.20.642
4c43FADFerredoxin--NADP reductase1.18.1.20.640
1ogiFADFerredoxin--NADP reductase1.18.1.20.639
1h42FADFerredoxin--NADP reductase1.18.1.20.624
1ogjFADFerredoxin--NADP reductase1.18.1.20.613
2b5oFADFerredoxin--NADP reductase1.18.1.20.611
1gr1FADFerredoxin--NADP reductase1.18.1.20.607
3zbtFADFerredoxin--NADP reductase1.18.1.20.606
1gjrFADFerredoxin--NADP reductase1.18.1.20.603
1go2FADFerredoxin--NADP reductase1.18.1.20.597
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.588
1b2rFADFerredoxin--NADP reductase1.18.1.20.584
3zc3FADFerredoxin--NADP reductase1.18.1.20.581
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.574
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.573
3vo2FADFerredoxin--NADP reductase/0.572
1ewyFADFerredoxin--NADP reductase1.18.1.20.566
1gawFADFerredoxin/0.563
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.555
2rc6FADFerredoxin--NADP reductase/0.554
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.554
1w35FADFerredoxin--NADP reductase1.18.1.20.553
1sm4FADFerredoxin--NADP reductase/0.552
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.552
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.549
1gaqFADFerredoxin/0.549
1w87FADFerredoxin--NADP reductase1.18.1.20.541
3w5uFADFerredoxin/0.540
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.527
3qfcFADNADPH--cytochrome P450 reductase/0.525
3qftFADNADPH--cytochrome P450 reductase/0.521
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.519
3fpkFADFerredoxin-NADP reductase/0.514
2rc5FADFerredoxin--NADP reductase/0.510
1amoFADNADPH--cytochrome P450 reductase/0.503
1j9zFADNADPH--cytochrome P450 reductase/0.503
3qfsFADNADPH--cytochrome P450 reductase/0.502
3jqrFADFerredoxin--NADP reductase, apicoplast/0.494
4yaoFADNADPH--cytochrome P450 reductase/0.494
1ja1FADNADPH--cytochrome P450 reductase/0.483
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.478
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.475
3ojxFADNADPH--cytochrome P450 reductase/0.474
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.474
5ah5LSSLeucine--tRNA ligase/0.470
4i101BSBeta-secretase 13.4.23.460.467
4n4wSNTSmoothened homolog/0.465
1g63FMNEpidermin decarboxylase4.1.10.463
4b7754MBeta-secretase 13.4.23.460.463
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.460
3iktNADRedox-sensing transcriptional repressor Rex/0.460
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.460
2ok8FADFerredoxin--NADP reductase, apicoplast/0.459
4j7hTRHPCZA361.3/0.459
5a4vQUEGlutathione S-transferase F22.5.1.180.459
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3zcbATPAdenosine monophosphate-protein transferase VbhT2.7.7.n10.458
4z87GDPInosine-5'-monophosphate dehydrogenase/0.458
1cqxFADFlavohemoprotein/0.457
5dp2NAPCurF/0.457
1gky5GPGuanylate kinase2.7.4.80.456
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2vd0D27Hematopoietic prostaglandin D synthase/0.456
4mprTPPBenzoylformate decarboxylase4.1.1.70.456
1qoqIGPTryptophan synthase alpha chain/0.455
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1f20FADNitric oxide synthase, brain1.14.13.390.454
2qe2452Polyprotein/0.454
3otwCOAPhosphopantetheine adenylyltransferase/0.454
2gjlFMNNitronate monooxygenase1.13.12.160.453
2ptfFMNUncharacterized protein MTH_863/0.453
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4bftZVTPantothenate kinase2.7.1.330.453
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.453
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.452
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.451
4bfuZVUPantothenate kinase2.7.1.330.451
1lnmDTXBilin-binding protein/0.450
1x1cSAHC-20 methyltransferase/0.450
1x2eATXProline iminopeptidase3.4.11.50.450
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.450
3fznD7KBenzoylformate decarboxylase4.1.1.70.450
3i0pNADMalate dehydrogenase, putative/0.450
3ivcFG4Pantothenate synthetase6.3.2.10.450
3rtnRTNBeta-secretase 13.4.23.460.450
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
1p4aPCPPur operon repressor/0.449
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1mvsDTMDihydrofolate reductase1.5.1.30.448
2vnjFADNADPH:ferredoxin reductase/0.448
3p2oNADBifunctional protein FolD/0.448
3phjDHKShikimate dehydrogenase (NADP(+))/0.448
4bfxZVXPantothenate kinase2.7.1.330.448
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.448
4iifCTSBeta-glucosidase 13.2.1.210.448
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.447
1yc2NADNAD-dependent protein deacylase 2/0.447
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.447
1r58AO5Methionine aminopeptidase 2/0.446
4bfvZVVPantothenate kinase2.7.1.330.446
3bw4FMNPutative 2-nitropropane dioxygenase/0.445
4acxS8ZBeta-secretase 13.4.23.460.445
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.445
1a8pFADFerredoxin--NADP reductase/0.444
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.444
3rgaILDEpoxide hydrolase LasB5.5.10.444
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.443
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.443
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.443
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.443
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.442
3n3aFMNProtein NrdI/0.442
4j7gTRHPCZA361.3/0.442
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.441
2vn1FK5Peptidylprolyl isomerase/0.441
3zoiM2WIsopenicillin N synthase1.21.3.10.441
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.441
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3ske054Genome polyprotein2.7.7.480.440
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.440
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440