Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e1xNW1Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1e1xNW1Cyclin-dependent kinase 22.7.11.221.000
1h0w207Cyclin-dependent kinase 22.7.11.220.560
4ek816KCyclin-dependent kinase 22.7.11.220.555
3rahO1ZCyclin-dependent kinase 22.7.11.220.548
3r8vZ62Cyclin-dependent kinase 22.7.11.220.522
1b38ATPCyclin-dependent kinase 22.7.11.220.521
2btrU73Cyclin-dependent kinase 22.7.11.220.520
1w8cN69Cyclin-dependent kinase 22.7.11.220.518
3r83Z14Cyclin-dependent kinase 22.7.11.220.516
5aniES4Cyclin-dependent kinase 22.7.11.220.516
4ek610KCyclin-dependent kinase 22.7.11.220.513
2a0cCK9Cyclin-dependent kinase 22.7.11.220.502
4fkg4CKCyclin-dependent kinase 22.7.11.220.500
4fkpLS5Cyclin-dependent kinase 22.7.11.220.500
3s0o50ZCyclin-dependent kinase 22.7.11.220.496
2a4lRRCCyclin-dependent kinase 22.7.11.220.495
2w06FRVCyclin-dependent kinase 22.7.11.220.493
2c6o4SPCyclin-dependent kinase 22.7.11.220.492
3r71X86Cyclin-dependent kinase 22.7.11.220.491
4fki09KCyclin-dependent kinase 22.7.11.220.490
4fklCK2Cyclin-dependent kinase 22.7.11.220.490
3lfqA28Cyclin-dependent kinase 22.7.11.220.489
1h1r6CPCyclin-dependent kinase 22.7.11.220.488
1oirHDYCyclin-dependent kinase 22.7.11.220.488
3r1yX76Cyclin-dependent kinase 22.7.11.220.488
3lfnA27Cyclin-dependent kinase 22.7.11.220.485
3iggEFQCyclin-dependent kinase 22.7.11.220.484
1pxmCK5Cyclin-dependent kinase 22.7.11.220.480
2w05FRTCyclin-dependent kinase 22.7.11.220.480
3r73X87Cyclin-dependent kinase 22.7.11.220.480
1ckpPVBCyclin-dependent kinase 22.7.11.220.479
1ke5LS1Cyclin-dependent kinase 22.7.11.220.479
1oitHDTCyclin-dependent kinase 22.7.11.220.479
1y91CT9Cyclin-dependent kinase 22.7.11.220.478
2exmZIPCyclin-dependent kinase 22.7.11.220.478
3qzgX67Cyclin-dependent kinase 22.7.11.220.478
3qu0X40Cyclin-dependent kinase 22.7.11.220.477
4eon1ROCyclin-dependent kinase 22.7.11.220.476
4fkq42KCyclin-dependent kinase 22.7.11.220.476
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.475
3rpo24ZCyclin-dependent kinase 22.7.11.220.473
1h0vUN4Cyclin-dependent kinase 22.7.11.220.471
1h1s4SPCyclin-dependent kinase 22.7.11.220.471
1b39ATPCyclin-dependent kinase 22.7.11.220.470
2xmyCDKCyclin-dependent kinase 22.7.11.220.470
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.469
3qwjX6ACyclin-dependent kinase 22.7.11.220.469
3rni21ZCyclin-dependent kinase 22.7.11.220.469
2btsU32Cyclin-dependent kinase 22.7.11.220.468
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.468
2r3o2SCCyclin-dependent kinase 22.7.11.220.465
4kd11QKCyclin-dependent kinase 22.7.11.220.465
3rk909ZCyclin-dependent kinase 22.7.11.220.464
3ezrEZRCyclin-dependent kinase 22.7.11.220.463
4fko20KCyclin-dependent kinase 22.7.11.220.462
1pxlCK4Cyclin-dependent kinase 22.7.11.220.460
2r3r6SCCyclin-dependent kinase 22.7.11.220.460
4bgh3I6Cyclin-dependent kinase 22.7.11.220.460
4eor4SPCyclin-dependent kinase 22.7.11.220.460
3sqq99ZCyclin-dependent kinase 22.7.11.220.459
1g5sI17Cyclin-dependent kinase 22.7.11.220.456
3qqhX0ACyclin-dependent kinase 22.7.11.220.456
1ke6LS2Cyclin-dependent kinase 22.7.11.220.455
2w1hL0FCyclin-dependent kinase 22.7.11.220.454
3rpr25ZCyclin-dependent kinase 22.7.11.220.454
1urwI1PCyclin-dependent kinase 22.7.11.220.453
2c69CT8Cyclin-dependent kinase 22.7.11.220.453
2b52D42Cyclin-dependent kinase 22.7.11.220.452
3rk708ZCyclin-dependent kinase 22.7.11.220.452
4lyn1YGCyclin-dependent kinase 22.7.11.220.452
1ykr628Cyclin-dependent kinase 22.7.11.220.451
3qqkX02Cyclin-dependent kinase 22.7.11.220.451
3r9hZ67Cyclin-dependent kinase 22.7.11.220.451
3unk0BYCyclin-dependent kinase 22.7.11.220.451
3sw418KCyclin-dependent kinase 22.7.11.220.450
4ez30S0Cyclin-dependent kinase 22.7.11.220.450
3qtzX42Cyclin-dependent kinase 22.7.11.220.449
3s2pPMUCyclin-dependent kinase 22.7.11.220.448
2r3jSCJCyclin-dependent kinase 22.7.11.220.447
3qqlX03Cyclin-dependent kinase 22.7.11.220.447
1di8DTQCyclin-dependent kinase 22.7.11.220.446
2vv9IM9Cyclin-dependent kinase 22.7.11.220.446
3r8lZ30Cyclin-dependent kinase 22.7.11.220.446
3r9nZ68Cyclin-dependent kinase 22.7.11.220.446
3rak03ZCyclin-dependent kinase 22.7.11.220.446
3roy22ZCyclin-dependent kinase 22.7.11.220.445
1gih1PUCyclin-dependent kinase 22.7.11.220.444
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.444
3qxoX65Cyclin-dependent kinase 22.7.11.220.444
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
2vtsLZCCyclin-dependent kinase 22.7.11.220.443
3raiX85Cyclin-dependent kinase 22.7.11.220.443
2uzoC62Cyclin-dependent kinase 22.7.11.220.442
3qtxX43Cyclin-dependent kinase 22.7.11.220.442
3r1sX73Cyclin-dependent kinase 22.7.11.220.442
3ddqRRCCyclin-dependent kinase 22.7.11.220.441
3unj0BXCyclin-dependent kinase 22.7.11.220.441
1w0xOLOCyclin-dependent kinase 22.7.11.220.440
2c6kDT2Cyclin-dependent kinase 22.7.11.220.440
3qtuX44Cyclin-dependent kinase 22.7.11.220.440