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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1drtPCVClavaminate synthase 11.14.11.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1drtPCVClavaminate synthase 11.14.11.211.000
2wouZZFTGF-beta receptor type-12.7.11.300.498
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.496
1nzfUPGDNA beta-glucosyltransferase/0.495
1nzdUPGDNA beta-glucosyltransferase/0.493
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.493
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.492
3ibqATPPyridoxal kinase/0.492
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.487
3uibSB2Putative mitogen-activated protein kinase/0.484
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.483
3h3t16HCollagen type IV alpha-3-binding protein/0.482
4pd6URINucleoside permease/0.482
2vkvTDCTetracycline repressor protein class D/0.480
1pq944BOxysterols receptor LXR-beta/0.479
2j2pSC2Ficolin-2/0.479
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2tctCTCTetracycline repressor protein class D/0.479
3junAKDPhenazine biosynthesis protein A/B/0.479
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
2o7oDXTTetracycline repressor protein class D/0.477
4btmF8ETau-tubulin kinase 12.7.11.10.476
1msmJE2Gag-Pol polyprotein3.4.23.160.475
2ahcVNLChorismate pyruvate-lyase/0.474
3h3qH13Collagen type IV alpha-3-binding protein/0.474
1j39UPGDNA beta-glucosyltransferase/0.472
2vwqNAPGlucose 1-dehydrogenase/0.471
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.471
1orkATCTetracycline repressor protein class D/0.470
1xddAAYIntegrin alpha-L/0.470
2rqfJH3Hemolymph juvenile hormone binding protein/0.470
3u9eCOALmo1369 protein/0.470
4k28NADShikimate dehydrogenase family protein/0.470
2wihP48Cyclin-dependent kinase 22.7.11.220.469
3r9nZ68Cyclin-dependent kinase 22.7.11.220.469
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.468
2xa4AZ5Tyrosine-protein kinase JAK2/0.468
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4xczFONQdtf/0.468
2xrlDXTTetracycline repressor protein class D/0.467
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.467
4y9qC2EUncharacterized protein/0.467
1h48CDI2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.466
1ovmTPPIndole-3-pyruvate decarboxylase4.1.1.740.466
2vttLZDCyclin-dependent kinase 22.7.11.220.466
2wxvWXVCyclin-dependent kinase 22.7.11.220.466
2y6o1N1Ephrin type-A receptor 42.7.10.10.466
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3mvjXFEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4b3aTACTetracycline repressor protein class D/0.466
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.466
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
4gk2L66Ephrin type-A receptor 32.7.10.10.465
2ghlLIBMitogen-activated protein kinase 14/0.464
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.464
2nnqT4BFatty acid-binding protein, adipocyte/0.464
2zjwREFCasein kinase II subunit alpha2.7.11.10.464
4z36ON3Lysophosphatidic acid receptor 1/0.464
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
3flwFLWMitogen-activated protein kinase 14/0.463
3fp0FP015-O-acetyltransferase/0.463
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4jhz1KVBeta-glucuronidase3.2.1.310.463
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1bwsNDPGDP-L-fucose synthase/0.462
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
1ykdCMPAdenylate cyclase/0.462
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.462
3flyFLYMitogen-activated protein kinase 14/0.462
4ewqMWLMitogen-activated protein kinase 14/0.462
4g3pUD1Bifunctional protein GlmU/0.462
4gk3L87Ephrin type-A receptor 32.7.10.10.462
5fkoTDCTetracycline repressor protein class D/0.462
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2bi4NADLactaldehyde reductase1.1.1.770.461
2iiqC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.461
2qtgMTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 13.2.2.90.461
3n0tOPYDipeptidyl peptidase 23.4.14.20.461
4d7mTDCTetracycline repressor protein class D/0.461
2pmnK51Protein kinase 7/0.460
2pxaSAHGenome polyprotein2.7.7.480.460
2rg5279Mitogen-activated protein kinase 14/0.460
3dj4UD1Bifunctional protein GlmU/0.460
3hk1B64Fatty acid-binding protein, adipocyte/0.460
3juqAJDPhenazine biosynthesis protein A/B/0.460
4a6bQG8Gag-Pol polyprotein3.4.23.160.460
4gd40WSLysine-specific demethylase 4A1.14.110.460
1ezvUQ6Cytochrome b/0.459
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.459
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.459
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
1k6pXN3Gag-Pol polyprotein3.4.23.160.458
1lf2R37Plasmepsin-23.4.23.390.458
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.458
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2qo9ANPEphrin type-A receptor 32.7.10.10.458
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2xdoFADTetX family tetracycline inactivation enzyme/0.458
2xyuQ9GEphrin type-A receptor 42.7.10.10.458
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.458
3fwjCAMCamphor 5-monooxygenase1.14.15.10.458
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.458
4gfvPRO_GLU_LEU_THR_PTRTyrosine-protein phosphatase non-receptor type 183.1.3.480.458
4qmySTUSerine/threonine-protein kinase 242.7.11.10.458
5fkmTDCTetracycline repressor protein class D/0.458
1tj0FADBifunctional protein PutA1.5.5.20.457
1w6hTITPlasmepsin-23.4.23.390.457
1w8cN69Cyclin-dependent kinase 22.7.11.220.457
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.457
2j9gANPBiotin carboxylase6.3.4.140.457
3fln3FNMitogen-activated protein kinase 14/0.457
3fr5I4AFatty acid-binding protein, adipocyte/0.457
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.457
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2ea4F79Methionine aminopeptidase 2/0.456
2pwrG4GGag-Pol polyprotein3.4.23.160.456
2w6zL21Biotin carboxylase6.3.4.140.456
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.456
3l9hEMQKinesin-like protein KIF11/0.456
3mpt1GKMitogen-activated protein kinase 14/0.456
3raiX85Cyclin-dependent kinase 22.7.11.220.456
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.456
4i231C9Epidermal growth factor receptor2.7.10.10.456
1c70L75Protease/0.455
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.455
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.455
3dogNNNCyclin-dependent kinase 22.7.11.220.455
3hv71AUMitogen-activated protein kinase 14/0.455
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.455
3nj0PYVAbscisic acid receptor PYL2/0.455
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
3tw6ADPPyruvate carboxylase/0.455
4z35ON9Lysophosphatidic acid receptor 1/0.455
1cjvDADAdenylate cyclase type 2/0.454
1cjvDADAdenylate cyclase type 5/0.454
2xpvMIYTetracycline repressor protein class D/0.454
2xpwOTCTetracycline repressor protein class D/0.454
3fg2FADPutative rubredoxin reductase/0.454
3lqfNADGalactitol dehydrogenase/0.454
4auxXTCTetracycline repressor protein class D/0.454
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.454
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.453
1wvySTUDeath-associated protein kinase 12.7.11.10.453
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.453
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.453
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.453
2c68CT6Cyclin-dependent kinase 22.7.11.220.453
2y3sTIRTamL/0.453
3c3eFO12-phospho-L-lactate transferase/0.453
4h1e10JBeta-secretase 13.4.23.460.453
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.453
5dibNADBetaine-aldehyde dehydrogenase/0.453
5e8ySTUTGF-beta receptor type-22.7.11.300.453
1ai9NDPDihydrofolate reductase1.5.1.30.452
1kzjCB3Thymidylate synthase/0.452
1yc443PHeat shock protein HSP 90-alpha/0.452
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.452
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.452
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.452
2fj1CTCTetracycline repressor protein class D/0.452
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.452
4dbzNDPPutative ketoacyl reductase1.3.10.452
4ddhMS0Pantothenate synthetase6.3.2.10.452
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
5cb4ACPTubulin tyrosine ligase/0.452
5fm7ADPRuvB-like helicase/0.452
1cbsREACellular retinoic acid-binding protein 2/0.451
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.451
2i40BLZCyclin-dependent kinase 22.7.11.220.451
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.451
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.451
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.451
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3kr8XAVTankyrase-22.4.2.300.451
3rdqDTBStreptavidin/0.451
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.451
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.451
4o4fATPKinase/0.451
4p9dTMPDeoxycytidylate deaminase/0.451
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.451
1cbqRE9Cellular retinoic acid-binding protein 2/0.450
1ia1NDPDihydrofolate reductase1.5.1.30.450
1rx1NAPDihydrofolate reductase1.5.1.30.450
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.450
2b53D23Cyclin-dependent kinase 22.7.11.220.450
2ea2F77Methionine aminopeptidase 2/0.450
2npxFADNADH peroxidase1.11.1.10.450
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3nefPYVAbscisic acid receptor PYL1/0.450
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.450
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.450
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.450
5e8wSTUTGF-beta receptor type-12.7.11.300.450
1dliUDXUDP-glucose 6-dehydrogenase/0.449
1e3eNAIAlcohol dehydrogenase 41.1.1.10.449
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.449
1fvv107Cyclin-dependent kinase 22.7.11.220.449
1k6tXN1Gag-Pol polyprotein3.4.23.160.449
1n77ATPGlutamate--tRNA ligase6.1.1.170.449
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
1x14NADNAD(P) transhydrogenase subunit alpha1.6.1.20.449
2btsU32Cyclin-dependent kinase 22.7.11.220.449
2ituITQEpidermal growth factor receptor2.7.10.10.449
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.449
2x0rNADMalate dehydrogenase/0.449
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.449
3qt62P0Mevalonate diphosphate decarboxylase/0.449
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.449
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.449
4g2fC07Ephrin type-A receptor 32.7.10.10.449
4jlm1NNDeoxycytidine kinase2.7.1.740.449
4m6jNDPDihydrofolate reductase1.5.1.30.449
1c6yMK1Protease/0.448
1trkTPPTransketolase 12.2.1.10.448
2c29NAPDihydroflavonol 4-reductase/0.448
2cdaNAPGlucose 1-dehydrogenase/0.448
2trtTACTetracycline repressor protein class D/0.448
2v13C40Renin3.4.23.150.448
2vu3LZECyclin-dependent kinase 22.7.11.220.448
3ed1GA3Gibberellin receptor GID1/0.448
3sptUD1Bifunctional protein GlmU/0.448
3uwqU5POrotidine 5'-phosphate decarboxylase/0.448
4b99R4LMitogen-activated protein kinase 72.7.11.240.448
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.448
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.448
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.448
4mv3ACPBiotin carboxylase6.3.4.140.448
4nm9FADBifunctional protein PutA/0.448
4xz3COAAcyl-CoA synthetase (NDP forming)/0.448
1g41ADPATP-dependent protease ATPase subunit HslU/0.447
1l8qADPChromosomal replication initiator protein DnaA/0.447
1pqc444Oxysterols receptor LXR-beta/0.447
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.447
2bl4NADLactaldehyde reductase1.1.1.770.447
2hk9NAPShikimate dehydrogenase (NADP(+))/0.447
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.447
2xrwANPMitogen-activated protein kinase 82.7.11.240.447
3anxMTAPolyamine aminopropyltransferase/0.447
3gbuATPUncharacterized sugar kinase PH14592.7.10.447
3iphG11Mitogen-activated protein kinase 14/0.447
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3vjoANPEpidermal growth factor receptor2.7.10.10.447
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4btjATPTau-tubulin kinase 12.7.11.10.447
4du82P0Mevalonate diphosphate decarboxylase/0.447
4f700STCyclin-dependent kinase 82.7.11.220.447
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.447
4o1pANPRibonuclease L/0.447
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.447
4zp1TPPPyruvate decarboxylase4.1.1.10.447
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.447
1bxoPP7Penicillopepsin-13.4.23.200.446
1np7FADCryptochrome DASH/0.446
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.446
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.446
2henADPEphrin type-B receptor 22.7.10.10.446
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.446
2q5oPPYIndole-3-pyruvate decarboxylase4.1.1.740.446
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2xs0ANPMitogen-activated protein kinase 82.7.11.240.446
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.446
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.446
3hllI45Mitogen-activated protein kinase 14/0.446
3hyz42CHeat shock protein HSP 90-alpha/0.446
3pe2E1BCasein kinase II subunit alpha2.7.11.10.446
3q1fYPPBeta-lactamase/0.446
3qlrNDPDihydrofolate reductase1.5.1.30.446
3v3vMYUMitogen-activated protein kinase 82.7.11.240.446
4a86H35Major pollen allergen Bet v 1-A/0.446
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bfvZVVPantothenate kinase2.7.1.330.446
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.446
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.446
4xj43ATCyclic GMP-AMP synthase/0.446
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1pxjCK2Cyclin-dependent kinase 22.7.11.220.445
1vyw292Cyclin-dependent kinase 22.7.11.220.445
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.445
2hckQUETyrosine-protein kinase HCK2.7.10.20.445
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.445
2p33J07Mitogen-activated protein kinase 102.7.11.240.445
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.445
2rhrEMOPutative ketoacyl reductase1.3.10.445
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3ddw055Glycogen phosphorylase, liver form2.4.1.10.445
3djjFADGlutathione reductase, mitochondrial1.8.1.70.445
3flzFLZMitogen-activated protein kinase 14/0.445
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
4cukNAID-lactate dehydrogenase/0.445
4f6w0SSCyclin-dependent kinase 82.7.11.220.445
4ho5DAUGlucose-1-phosphate thymidylyltransferase/0.445
4ho9GDUGlucose-1-phosphate thymidylyltransferase/0.445
4jq7KJQEpidermal growth factor receptor2.7.10.10.445
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.445
4looSB4Mitogen-activated protein kinase 14/0.445
4lz81YXGlutamate receptor 2/0.445
4uirFADOleate hydratase4.2.1.530.445
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.445
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.444
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.444
1meiMOAInosine-5'-monophosphate dehydrogenase/0.444
1pjcNADAlanine dehydrogenase/0.444
1tkaN3TTransketolase 12.2.1.10.444
2ab8MTPAdenosine kinase2.7.1.200.444
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.444
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.444
2qnqQN3Gag-Pol polyprotein3.4.23.160.444
2vx07X7Ephrin type-B receptor 42.7.10.10.444
2w3aTOPDihydrofolate reductase1.5.1.30.444
2xf3J01Uncharacterized protein/0.444
2zjmF1MBeta-secretase 13.4.23.460.444
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3eldSFGMethyltransferase/0.444
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3ov4EQUSteroid Delta-isomerase5.3.3.10.444
3tm5SFGUncharacterized protein/0.444
3tn8F18Cyclin-dependent kinase 92.7.11.220.444
4aa4QC0Mitogen-activated protein kinase 14/0.444
4cvlACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.444
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.444
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.444
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.444
1kh3ANPArgininosuccinate synthase/0.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.443
2hog710Serine/threonine-protein kinase Chk12.7.11.10.443
2ohvNHLGlutamate racemase/0.443
3akm11DFatty acid-binding protein, intestinal/0.443
3bhtMFRCyclin-dependent kinase 22.7.11.220.443
3cvuFADRE11660p/0.443
3h3sH15Collagen type IV alpha-3-binding protein/0.443
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3ixp834Ecdysone receptor/0.443
3l5dBDVBeta-secretase 13.4.23.460.443
3q5dGDPAtlastin-13.6.50.443
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4dpy2P0Mevalonate diphosphate decarboxylase/0.443
4j57FADThioredoxin reductase 21.8.1.90.443
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.443
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.443
5k0t415Methionine--tRNA ligase/0.443
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.442
1bozPRDDihydrofolate reductase1.5.1.30.442
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.442
1e3lNADAlcohol dehydrogenase 41.1.1.10.442
1ia3TQ5Dihydrofolate reductase1.5.1.30.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.442
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1w2xRCPAcetyl-CoA carboxylase/0.442
2cy0NAPShikimate dehydrogenase (NADP(+))/0.442
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.442
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.442
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.442
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.442
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.442
3rvhHQ2Lysine-specific demethylase 4A1.14.110.442
3t6iNC8Endothiapepsin3.4.23.220.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
3tnlNADShikimate dehydrogenase (NADP(+))/0.442
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
4a862ANMajor pollen allergen Bet v 1-A/0.442
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ho8UPGGlucose-1-phosphate thymidylyltransferase/0.442
4kfbT27Gag-Pol polyprotein2.7.7.490.442
4opgFDAConserved Archaeal protein/0.442
4tm0FADKtzI/0.442
4xb2NDP319aa long hypothetical homoserine dehydrogenase/0.442
4zolACPTubulin tyrosine ligase/0.442
5il1SAMN6-adenosine-methyltransferase 70 kDa subunit/0.442
4z34ON7Lysophosphatidic acid receptor 1/0.442
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1g1aNADdTDP-glucose 4,6-dehydratase/0.441
1hbvGANGag-Pol polyprotein/0.441
1k6cMK1Gag-Pol polyprotein3.4.23.160.441
1rjeSAHLeucine carboxyl methyltransferase 12.1.1.2330.441
1tytFADTrypanothione reductase1.8.1.120.441
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
1y9dTPPPyruvate oxidase1.2.3.30.441
2ibzUQ6Cytochrome b/0.441
2vprTDCTetracycline repressor protein class H/0.441
3gonANPPhosphomevalonate kinase/0.441
3hvcGG5Mitogen-activated protein kinase 14/0.441
3i7eDJRGag-Pol polyprotein/0.441
4c02TAKActivin receptor type-12.7.11.300.441
4djw0KPBeta-secretase 13.4.23.460.441
4gt3ATPMitogen-activated protein kinase 12.7.11.240.441
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.441
1c3eGARPhosphoribosylglycinamide formyltransferase/0.440
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1esqTZPHydroxyethylthiazole kinase/0.440
1h51FMNPentaerythritol tetranitrate reductase/0.440
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.440
2balPQAMitogen-activated protein kinase 14/0.440
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.440
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.440
2ijmADPFocal adhesion kinase 12.7.10.20.440
2nv4SAMS-adenosyl-L-methionine-binding protein AF_0241/0.440
2qc8ADPGlutamine synthetase6.3.1.20.440
2rlcCHDCholoylglycine hydrolase3.5.1.240.440
2tpsTPSThiamine-phosphate synthase/0.440
2wpxACOOrf14/0.440
2xgoZKDUncharacterized protein/0.440
2y60M8FIsopenicillin N synthase1.21.3.10.440
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.440
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3smkCW714-3-3 protein sigma/0.440
3tjzGNPADP-ribosylation factor 1/0.440
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4baqM4ZProthrombin3.4.21.50.440
4btjADPTau-tubulin kinase 12.7.11.10.440
4dxd9PCCell division protein FtsZ/0.440
4ihl1F514-3-3 protein zeta/delta/0.440
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.440
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.440
4nmbFADBifunctional protein PutA/0.440
4oztP1AEcdysone receptor, putative/0.440
4qysPLRTryptophan synthase beta chain 24.2.1.200.440
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.440