sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 1.000 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.653 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.644 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.630 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.611 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.528 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.513 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.513 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.510 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.510 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.508 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.507 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.504 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.504 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.503 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.501 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.500 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.496 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.496 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.493 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.493 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.492 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.491 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.491 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.490 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.490 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.488 | |
| 2ejz | SAH | Diphthine synthase | / | 0.488 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.488 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.488 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.487 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.487 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.486 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.485 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.482 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.482 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.482 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.482 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.481 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.481 | |
| 3b9l | AZZ | Serum albumin | / | 0.481 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.480 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.480 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.479 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.479 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.479 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.478 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.478 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.478 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.477 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.477 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.476 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.475 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.474 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.473 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.473 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.473 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 1jqi | CAA | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.472 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.472 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.472 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.472 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.471 | |
| 1osv | CHC | Bile acid receptor | / | 0.471 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.471 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.471 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.471 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.470 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.470 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.470 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.469 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.469 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.469 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.468 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.468 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.468 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.468 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.468 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.467 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.467 | |
| 2xvv | 9DN | Serum albumin | / | 0.467 | |
| 3e8x | NAP | BH1520 protein | / | 0.467 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.467 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.467 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.466 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.466 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.466 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.465 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.465 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.465 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.464 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.464 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.464 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.463 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.463 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.463 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.463 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.463 | |
| 1dtp | APU | Diphtheria toxin | / | 0.462 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.462 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.461 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.461 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.461 | |
| 3u8m | 09R | Acetylcholine-binding protein | / | 0.461 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.461 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.461 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.461 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.460 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.460 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.460 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.460 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.459 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.459 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.459 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4e2d | FMN | Dehydrogenase | / | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.458 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.458 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.458 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.458 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.458 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.458 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.458 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.457 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.457 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.457 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.457 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.457 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.457 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.457 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.457 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.457 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.457 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.457 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.457 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.457 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.457 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.456 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.456 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.456 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.456 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.456 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2p15 | EZT | Estrogen receptor | / | 0.456 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3eej | 53R | Uncharacterized protein | / | 0.456 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.456 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.456 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.456 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.456 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.455 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.455 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2dxv | SAH | Diphthine synthase | / | 0.455 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.455 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.455 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.455 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.454 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.454 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.454 | |
| 3eku | CY9 | Actin-5C | / | 0.454 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.454 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.454 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.454 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4nvk | 2NY | Peroxidase | / | 0.454 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.454 | |
| 1jha | AAM | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.453 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.453 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2bxm | IMN | Serum albumin | / | 0.453 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.453 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.453 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.453 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.453 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.453 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.453 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.453 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.453 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.453 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.453 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.453 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.453 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.453 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.452 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.452 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.452 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.452 | |
| 2dsg | SAH | Diphthine synthase | / | 0.452 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.452 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.452 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.452 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.452 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.452 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.452 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.452 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.452 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.452 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.452 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.452 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.452 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.452 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.451 | |
| 1wng | SAH | Diphthine synthase | / | 0.451 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.451 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.451 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.451 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.451 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.451 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.450 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.450 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.450 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 1yvf | PH7 | Polyprotein | / | 0.450 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.450 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 2ohv | NHL | Glutamate racemase | / | 0.450 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.450 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4l9q | 9TP | Serum albumin | / | 0.450 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.450 | |
| 4phl | PIL | Phosphodiesterase | / | 0.450 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.450 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.449 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.449 | |
| 1r2j | FAD | FkbI | / | 0.449 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.449 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2hux | SAH | Diphthine synthase | / | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.449 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.449 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.449 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.449 | |
| 3isi | B88 | Putative dipeptidase | / | 0.449 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.449 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.448 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.448 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.448 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.448 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.448 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4mpp | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.448 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.448 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.447 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2ejj | SAH | Diphthine synthase | / | 0.447 | |
| 2emr | SAH | Diphthine synthase | / | 0.447 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.447 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.447 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.447 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.447 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.447 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.447 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.447 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.447 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.446 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.446 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.446 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.446 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.446 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.446 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.446 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.446 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.446 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.446 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.446 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.445 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.445 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.445 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.445 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.445 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 1e7a | PFL | Serum albumin | / | 0.444 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.444 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.444 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.444 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2emu | SAH | Diphthine synthase | / | 0.444 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.444 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.444 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.444 | |
| 2pch | SAH | Diphthine synthase | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.444 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.444 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.444 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4egn | TWO | Cytochrome P450 | / | 0.444 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4o67 | 1SY | Cyclic GMP-AMP synthase | / | 0.444 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.444 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.444 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.444 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.444 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.444 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.444 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2e08 | SAH | Diphthine synthase | / | 0.443 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.443 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.443 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.443 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.443 | |
| 2v1a | FMN | NPH1-1 | / | 0.443 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.443 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.443 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.443 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.443 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.443 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.442 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.442 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.442 | |
| 1u5a | BIK | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.442 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 2e8h | SAH | Diphthine synthase | / | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.442 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.442 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.442 | |
| 2vpy | MGD | Thiosulfate reductase | / | 0.442 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.442 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.442 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.442 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.442 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3hpq | AP5 | Adenylate kinase | / | 0.442 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.442 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.442 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.442 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.442 | |
| 4dqw | ATP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.442 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.442 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.442 | |
| 1efa | NPF | Lactose operon repressor | / | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.441 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.441 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.441 | |
| 1u28 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.441 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2e8q | SAH | Diphthine synthase | / | 0.441 | |
| 2ejk | SAH | Diphthine synthase | / | 0.441 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.441 | |
| 2p9d | SAH | Diphthine synthase | / | 0.441 | |
| 2pcm | SAH | Diphthine synthase | / | 0.441 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.441 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.441 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.441 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.441 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.441 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.441 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.440 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1xq3 | R18 | Androgen receptor | / | 0.440 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2egl | SAH | Diphthine synthase | / | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2p2x | SAH | Diphthine synthase | / | 0.440 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.440 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.440 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.440 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.440 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.440 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.440 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.440 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.440 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.440 |