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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1c1wBAHProthrombin3.4.21.5

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1c1wBAHProthrombin3.4.21.51.000
2cn0F25Prothrombin3.4.21.50.558
2cf8ESHProthrombin3.4.21.50.532
1ta6177Prothrombin3.4.21.50.523
1oytFSNProthrombin3.4.21.50.516
1c4yIH3Prothrombin3.4.21.50.505
2cf9348Prothrombin3.4.21.50.490
1yplRA8Prothrombin3.4.21.50.486
2anmCDOProthrombin3.4.21.50.486
1ypeUIPProthrombin3.4.21.50.480
2jh6894Prothrombin3.4.21.50.480
2v3oI26Prothrombin3.4.21.50.479
2zfr46UProthrombin3.4.21.50.476
1ypgUIRProthrombin3.4.21.50.475
1umaIN2Prothrombin3.4.21.50.470
1mu6CDAProthrombin3.4.21.50.469
2jh0701Prothrombin3.4.21.50.466
1d9i00PProthrombin3.4.21.50.465
1gj5130Prothrombin3.4.21.50.461
1o2g696Prothrombin3.4.21.50.457
1zgi382Prothrombin3.4.21.50.457
2zi224UProthrombin3.4.21.50.457
2gdeSN3Prothrombin3.4.21.50.455
1d6w00RProthrombin3.4.21.50.454
4ax9N5NProthrombin3.4.21.50.453
1z71L17Prothrombin3.4.21.50.446
1nm6L86Prothrombin3.4.21.50.440