sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1c1d	NAI	Phenylalanine dehydrogenase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1c1d	NAI	Phenylalanine dehydrogenase	/	1.000
1bw9	NAD	Phenylalanine dehydrogenase	/	0.535
4xgi	NAD	Glutamate dehydrogenase	/	0.468
5ijz	NAP	NADP-specific glutamate dehydrogenase	1.4.1.4	0.449
3hwr	NDP	2-dehydropantoate 2-reductase	/	0.443
5bsg	NAP	Pyrroline-5-carboxylate reductase	/	0.443
3etd	NDP	Glutamate dehydrogenase 1, mitochondrial	1.4.1.3	0.442
4dx7	DM2	Multidrug efflux pump subunit AcrB	/	0.442
3ggo	NAI	Prephenate dehydrogenase	/	0.441
3nug	NAD	Pyridoxal 4-dehydrogenase	1.1.1.107	0.441