sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bmk | SB5 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 1bl7 | SB4 | Mitogen-activated protein kinase 14 | / | 0.666 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.556 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.518 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.518 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.513 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.511 | |
| 2y3s | TIR | TamL | / | 0.508 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.503 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.501 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.500 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.500 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.499 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.499 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.499 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.497 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.497 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.496 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.496 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.494 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.493 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.491 | |
| 2y3r | TRK | TamL | / | 0.490 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.490 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.490 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 4do0 | DZA | Histone lysine demethylase PHF8 | 1.14.11.27 | 0.487 | |
| 1c6z | ROC | Protease | / | 0.486 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.485 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.484 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 1hvh | Q82 | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.483 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
| 1c6x | 3IN | Protease | / | 0.482 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.482 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 1mer | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.481 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.481 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.479 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.479 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.478 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.478 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.478 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.476 | |
| 1hxw | RIT | Gag-Pol polyprotein | / | 0.476 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.476 | |
| 1wbk | 568 | Pol protein | / | 0.476 | |
| 2hs2 | 017 | Protease | / | 0.476 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1odw | 0E8 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 2nnp | ROC | Protease | / | 0.474 | |
| 2qhc | AB1 | Protease | / | 0.474 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.474 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.474 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 3fsf | FSS | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.473 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.473 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3sa3 | 23X | Protease | / | 0.472 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1b6p | PI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 1mes | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 1siv | PSI | Gag-Pol polyprotein | / | 0.470 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2bpx | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.469 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 1tcw | IM1 | Gag-Pol polyprotein | / | 0.468 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.468 | |
| 2upj | U02 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.468 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.468 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.468 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.468 | |
| 1izi | Q50 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2i4x | KGQ | Protease | / | 0.467 | |
| 4h03 | LAR | Actin, alpha skeletal muscle | / | 0.467 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.467 | |
| 1d4j | MSC | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1z1h | HBB | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2aqu | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2i4u | DJR | Protease | / | 0.466 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.466 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 4h6p | FMN | Chromate reductase | / | 0.466 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.465 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.465 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 2p3a | 3TL | Pol protein | / | 0.465 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.465 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.465 | |
| 3saa | 77F | Protease | / | 0.465 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.464 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.464 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.464 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 1h48 | CDI | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.463 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.463 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.463 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.463 | |
| 3qbf | JHG | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.463 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4njs | G08 | Protease | / | 0.462 | |
| 4njv | RIT | Protease | / | 0.462 | |
| 2b7z | MK1 | Gag-Pol polyprotein | / | 0.461 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3gc7 | B45 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.461 | |
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.461 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.461 | |
| 4djq | M86 | Pol polyprotein | / | 0.461 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.461 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.461 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1d4y | TPV | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1ida | 0PO | Gag-Pol polyprotein | 3.4.23.47 | 0.460 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.460 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.460 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2aid | THK | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 2fdd | 385 | Pol protein | / | 0.460 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.460 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.460 | |
| 2qci | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.460 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.460 | |
| 1c6y | MK1 | Protease | / | 0.459 | |
| 1hpo | UNI | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1mui | AB1 | Protease | / | 0.459 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2bpz | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2hb3 | GRL | Protease | / | 0.459 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2qak | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3mv5 | XFE | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.459 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 3wec | AUI | Cytochrome P450 | / | 0.459 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.459 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1ajx | AH1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1dmp | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2bo7 | GDP | Mannosylglycerate synthase | / | 0.458 | |
| 2i4w | KGQ | Protease | / | 0.458 | |
| 2ieo | 017 | Protease | / | 0.458 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3ckt | YDP | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.458 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.458 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.458 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.458 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.458 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.458 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.457 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.457 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.457 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.457 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.457 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.457 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.457 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1bwa | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1g35 | AHF | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.456 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.456 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3kf0 | 3TL | Gag-Pol polyprotein | / | 0.456 | |
| 3s43 | 478 | Protease | / | 0.456 | |
| 3s54 | 017 | Protease | / | 0.456 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.456 | |
| 4dqe | 017 | Gag-Pol polyprotein | / | 0.456 | |
| 1h48 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.455 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.455 | |
| 1mtr | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.455 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 1qbu | 846 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.455 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 2idw | 017 | Protease | / | 0.455 | |
| 2pqz | G0G | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2qi0 | MZ3 | Gag-Pol polyprotein | / | 0.455 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3o9a | K14 | Pol polyprotein | / | 0.455 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.455 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4dqb | 017 | Gag-Pol polyprotein | / | 0.455 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 1ec0 | BED | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 1hvk | A79 | Gag-Pol polyprotein | / | 0.454 | |
| 1hwr | 216 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.454 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.454 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.454 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.454 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.454 | |
| 3d1z | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.454 | |
| 3jw2 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.454 | |
| 3mws | 017 | Pol protein | / | 0.454 | |
| 3nu9 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.453 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.453 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.453 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.453 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.452 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1hvr | XK2 | Gag-Pol polyprotein | / | 0.452 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.452 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3bxs | DRS | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3djk | G55 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3qai | XNN | Ketohexokinase | / | 0.452 | |
| 3qih | FG7 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.452 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.452 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.452 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.451 | |
| 2bqv | A1A | Protease | / | 0.451 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2f80 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2q29 | ACO | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.451 | |
| 2r5p | MK1 | Gag-Pol polyprotein | / | 0.451 | |
| 2rkf | AB1 | Pol protein | / | 0.451 | |
| 2uxz | HI1 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3ekw | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 4hla | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.451 | |
| 1sdt | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2a4f | AAU | V-1 protease | / | 0.450 | |
| 2q54 | MU1 | Protease | / | 0.450 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.450 | |
| 3a2o | KNJ | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 3nu4 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3o99 | K13 | Pol polyprotein | / | 0.450 | |
| 3q92 | XNB | Ketohexokinase | / | 0.450 | |
| 3qih | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.450 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.450 | |
| 4gb2 | 0LQ | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 4k4p | 3TL | Gag-Pol polyprotein | / | 0.450 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.450 | |
| 5upj | UIN | Gag-Pol polyprotein | / | 0.450 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1bai | 0Q4 | Gag-Pro polyprotein | / | 0.449 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.449 | |
| 1qbt | 146 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.449 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.449 | |
| 2qi7 | MZ9 | Gag-Pol polyprotein | / | 0.449 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 3nu5 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.449 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4njt | 017 | Protease | / | 0.449 | |
| 4q1w | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1daz | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.448 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 1u28 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.448 | |
| 2hc0 | AB2 | Protease | / | 0.448 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3o9c | K20 | Pol polyprotein | / | 0.448 | |
| 3orn | 3OR | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 3sa5 | A69 | Protease | / | 0.448 | |
| 3so9 | 017 | Pol protein | / | 0.448 | |
| 3vf7 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.448 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1bdq | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.447 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2i4d | QFI | Protease | / | 0.447 | |
| 2wpx | ACO | Orf14 | / | 0.447 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3ndj | JHZ | Methyltransferase | / | 0.447 | |
| 3nxe | 2NC | Protease | / | 0.447 | |
| 3vhe | 42Q | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4jsy | GTP | Metallophosphoesterase | / | 0.447 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.447 | |
| 4q1y | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1d4k | PI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1d4l | PI9 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1ebw | BEI | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.446 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.446 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1w5v | BE3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2o12 | FMN | Chorismate synthase | / | 0.446 | |
| 2qd6 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3o9g | F53 | Gag-Pol polyprotein | / | 0.446 | |
| 3oc1 | BMU | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.446 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.446 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.446 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.446 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.446 | |
| 5cvc | PLP | Serine racemase | / | 0.446 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 7upj | INU | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1b6m | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1bwb | 146 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.445 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.445 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.445 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2z4o | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3cvu | FAD | RE11660p | / | 0.445 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.445 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3sa9 | A68 | Protease | / | 0.445 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4onq | SFG | DNA methyltransferase | / | 0.445 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.445 | |
| 1ajv | NMB | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1izh | Q50 | Protease | / | 0.444 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.444 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.444 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.444 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2hs1 | 017 | Protease | / | 0.444 | |
| 2qnn | QN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.444 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.444 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3nls | 016 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.444 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.444 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.443 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 1onp | FOM | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.443 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1wbm | BLL | Pol protein | / | 0.443 | |
| 2avm | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2pyn | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.443 | |
| 3el0 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.443 | |
| 3qpj | N4I | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3u9e | COA | Lmo1369 protein | / | 0.443 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1ebk | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1hpv | 478 | Gag-Pol polyprotein | / | 0.442 | |
| 1njc | DCM | Thymidylate synthase | / | 0.442 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.442 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2i4v | DJR | V-1 protease | / | 0.442 | |
| 2q5k | AB1 | Protease | / | 0.442 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.442 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 3ekt | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3gi4 | K60 | Gag-Pol polyprotein | / | 0.442 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3oxw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.442 | |
| 3zux | TCH | Transporter | / | 0.442 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.442 | |
| 4eh5 | 0OM | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4hdb | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 4hjf | C2E | GGDEF family protein | / | 0.442 | |
| 4jld | ADP | Adenylate kinase | / | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1fgc | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.441 | |
| 1met | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.441 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1qbr | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1tcx | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2a1y | 5GP | GMP reductase | / | 0.441 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2exl | GDM | Endoplasmin | / | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 2pwr | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.441 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.441 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.441 | |
| 3tof | 076 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.441 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.441 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2q6b | HR2 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 2y4g | TIR | TamL | / | 0.440 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.440 | |
| 3d20 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.440 | |
| 3flq | 891 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3jvw | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.440 | |
| 3oxx | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.440 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.440 | |
| 4oti | MI1 | Serine/threonine-protein kinase N1 | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 |