sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bl7 | SB4 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1bl7 | SB4 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.595 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.527 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.519 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.513 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.491 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 1oz1 | FPH | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3gc7 | B45 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3oc1 | BMU | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3fsf | FSS | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 1hvh | Q82 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2f3k | RO1 | Protease | / | 0.443 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.443 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4z07 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.442 | |
| 1c6z | ROC | Protease | / | 0.441 | |
| 1c70 | L75 | Protease | / | 0.441 | |
| 2vwp | NDP | Glucose 1-dehydrogenase | / | 0.441 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4dlj | 6RG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.440 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.440 |