sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1aqx	GTD	Glutathione S-transferase P	2.5.1.18

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1aqx	GTD	Glutathione S-transferase P	2.5.1.18	1.000
1gti	GTB	Glutathione S-transferase P 1	2.5.1.18	0.619
1pgt	GTX	Glutathione S-transferase P	2.5.1.18	0.556
12gs	0HH	Glutathione S-transferase P	2.5.1.18	0.550
13gs	SAS	Glutathione S-transferase P	2.5.1.18	0.550
2oa7	GTX	Glutathione S-transferase P 1	2.5.1.18	0.539
3pgt	GBX	Glutathione S-transferase P	2.5.1.18	0.532
3ie3	N11	Glutathione S-transferase P	2.5.1.18	0.527
20gs	CBD	Glutathione S-transferase P	2.5.1.18	0.525
3gus	N11	Glutathione S-transferase P	2.5.1.18	0.513
2a2s	GSN	Glutathione S-transferase P	2.5.1.18	0.505
3csj	CBL	Glutathione S-transferase P	2.5.1.18	0.502
2glr	GTX	Glutathione S-transferase P 1	2.5.1.18	0.501
2j9h	GTX	Glutathione S-transferase P	2.5.1.18	0.482
2oad	GTB	Glutathione S-transferase P 1	2.5.1.18	0.473
1aqv	0HG	Glutathione S-transferase P	2.5.1.18	0.470
9gss	GTX	Glutathione S-transferase P	2.5.1.18	0.457
2pgt	GPR	Glutathione S-transferase P	2.5.1.18	0.451