sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 1.000 | |
| 1x28 | PGU | Aspartate aminotransferase | 2.6.1.1 | 0.575 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.557 | |
| 1maq | PGU | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.546 | |
| 2ay5 | IOP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.532 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.521 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.520 | |
| 1arg | PPD | Aspartate aminotransferase | 2.6.1.1 | 0.517 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.513 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.512 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.508 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.505 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.501 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.491 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.490 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.485 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.482 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.472 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.472 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.464 | |
| 2ay2 | CXP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.463 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.452 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 |