Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1a4zNADAldehyde dehydrogenase, mitochondrial1.2.1.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1a4zNADAldehyde dehydrogenase, mitochondrial1.2.1.31.000
4i8pNADAminoaldehyde dehydrogenase 1/0.585
2bhpNAD1-pyrroline-5-carboxylate dehydrogenase/0.574
4fqfNADAldehyde dehydrogenase, mitochondrial1.2.1.30.565
4pz2NADAldehyde dehydrogenase 2-6/0.561
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.558
1o04NADAldehyde dehydrogenase, mitochondrial1.2.1.30.556
2onmNADAldehyde dehydrogenase, mitochondrial1.2.1.30.545
4v37NADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.541
1o00NADAldehyde dehydrogenase, mitochondrial1.2.1.30.525
4pt0NADAldehyde dehydrogenase/0.522
2onpNADAldehyde dehydrogenase, mitochondrial1.2.1.30.521
3hazNADBifunctional protein PutA/0.506
1ez0NAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.473
2jg7NADAntiquitin/0.470
1uxvNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.458
4wb9NAIRetinal dehydrogenase 11.2.1.360.458
3rhqNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.448
1wnbNAIGamma-aminobutyraldehyde dehydrogenase1.2.1.190.446