sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
10mh	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
10mh	SAH	Modification methylase HhaI	2.1.1.37	1.000
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.647
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.639
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.614
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.591
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.583
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.575
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.572
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.569
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.556
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.530
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.512