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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
9mhtSAHModification methylase HhaI2.1.1.37

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
9mhtSAHModification methylase HhaI2.1.1.371.000
7mhtSAHModification methylase HhaI2.1.1.370.647
2uyhSAHModification methylase HhaI2.1.1.370.637
5mhtSAHModification methylase HhaI2.1.1.370.619
1skmSAHModification methylase HhaI2.1.1.370.613
8mhtSAHModification methylase HhaI2.1.1.370.611
2c7qSAHModification methylase HhaI2.1.1.370.602
2i9kSAHModification methylase HhaI2.1.1.370.591
10mhSAHModification methylase HhaI2.1.1.370.581
2zcjSAHModification methylase HhaI2.1.1.370.580
1mhtSAHModification methylase HhaI2.1.1.370.579
2z6uSAHModification methylase HhaI2.1.1.370.577
1fjxSAHModification methylase HhaI2.1.1.370.574
4mhtSAHModification methylase HhaI2.1.1.370.558
3mhtSAHModification methylase HhaI2.1.1.370.542
2hmySAMModification methylase HhaI2.1.1.370.518
3qv2SAH5-cytosine DNA methyltransferase/0.446