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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
8mhtSAHModification methylase HhaI2.1.1.37

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
8mhtSAHModification methylase HhaI2.1.1.371.000
5mhtSAHModification methylase HhaI2.1.1.370.795
2uyhSAHModification methylase HhaI2.1.1.370.660
9mhtSAHModification methylase HhaI2.1.1.370.651
2z6uSAHModification methylase HhaI2.1.1.370.642
7mhtSAHModification methylase HhaI2.1.1.370.611
3mhtSAHModification methylase HhaI2.1.1.370.607
2zcjSAHModification methylase HhaI2.1.1.370.600
1skmSAHModification methylase HhaI2.1.1.370.599
2c7qSAHModification methylase HhaI2.1.1.370.589
1mhtSAHModification methylase HhaI2.1.1.370.585
4mhtSAHModification methylase HhaI2.1.1.370.570
10mhSAHModification methylase HhaI2.1.1.370.568
2i9kSAHModification methylase HhaI2.1.1.370.551
1fjxSAHModification methylase HhaI2.1.1.370.542
2hmySAMModification methylase HhaI2.1.1.370.515
3qv2SAH5-cytosine DNA methyltransferase/0.473
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.456
4h0nSAHDnmt2/0.450