Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 1.000 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.795 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.660 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.651 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.642 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.611 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.607 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.600 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.599 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.589 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.585 | |
| 4mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.570 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.568 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.551 | |
| 1fjx | SAH | Modification methylase HhaI | 2.1.1.37 | 0.542 | |
| 2hmy | SAM | Modification methylase HhaI | 2.1.1.37 | 0.515 | |
| 3qv2 | SAH | 5-cytosine DNA methyltransferase | / | 0.473 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.456 | |
| 4h0n | SAH | Dnmt2 | / | 0.450 |