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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5je4SAHMethyl transferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5je4SAHMethyl transferase/1.000
5je3SAHMethyl transferase/0.661
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.516
1jqdSAHHistamine N-methyltransferase2.1.1.80.482
3bgvSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.476
5bp9SAHPutative methyltransferase protein/0.468
2aotSAHHistamine N-methyltransferase2.1.1.80.462
4uy6SAHHistidine N-alpha-methyltransferase/0.459
4iv8SAMPhosphoethanolamine N-methyltransferase,putative/0.455
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.450
3p9kSAHCaffeic acid O-methyltransferase/0.443
2xvmSAHTellurite methyltransferase2.1.1.2650.441
2hv9SFGmRNA cap guanine-N7 methyltransferase2.1.1.560.440