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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5htxADPPutative xylulose kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5htxADPPutative xylulose kinase/1.000
5htpANPProbable sugar kinase/0.591
2yyyNAPGlyceraldehyde-3-phosphate dehydrogenase1.2.1.590.494
3rmf20ZCyclin-dependent kinase 22.7.11.220.492
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.490
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.490
2q7vFADThioredoxin reductase/0.484
2zoq5IDMitogen-activated protein kinase 32.7.11.240.484
1cs4GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.480
1svwGTPProbable GTP-binding protein EngB/0.479
3ral04ZCyclin-dependent kinase 22.7.11.220.478
3n83ADPAldehyde dehydrogenase, mitochondrial1.2.1.30.476
4zohFADPutative oxidoreductase FAD-binding subunit/0.476
2hb7O1CVitamin D3 receptor/0.475
2cduFADNADH oxidase/0.471
4gub0Y4Casein kinase II subunit alpha2.7.11.10.471
2gr0FADFerredoxin reductase/0.470
2zb3NDPProstaglandin reductase 21.3.1.480.470
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.470
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.470
3s1h56ZCyclin-dependent kinase 22.7.11.220.469
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.469
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
1npvL27Gag-Pol polyprotein3.4.23.160.468
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.468
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.467
2fzmFADBifunctional protein PutA1.5.5.20.467
4g170VNCasein kinase I isoform gamma-32.7.11.10.467
4yswFADXanthine dehydrogenase/oxidase/0.467
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.467
1d7lRFLp-hydroxybenzoate hydroxylase/0.465
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.465
2hqpNDPDihydrofolate reductase1.5.1.30.464
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.464
3s55NADPutative short-chain dehydrogenase/reductase/0.464
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.464
2fzwNADAlcohol dehydrogenase class-31.1.1.10.463
2xhd7T9Glutamate receptor 2/0.463
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.463
3ggu017Gag-Pol polyprotein3.4.23.160.463
3ik6HCZGlutamate receptor 2/0.463
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.463
4nyeADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.463
1cbsREACellular retinoic acid-binding protein 2/0.462
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.462
2givACOHistone acetyltransferase KAT8/0.462
2i0aMUIProtease/0.462
2x3nFADProbable FAD-dependent monooxygenase/0.462
3iewCTP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.462
3iggEFQCyclin-dependent kinase 22.7.11.220.462
3pqbVGPPutative oxidoreductase/0.462
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.462
2oz6CMPCyclic AMP receptor-like protein/0.461
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.461
3cukFADD-amino-acid oxidase1.4.3.30.461
3gubGUBDeath-associated protein kinase 12.7.11.10.461
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4ivd15TTyrosine-protein kinase JAK1/0.461
1mesDMPGag-Pol polyprotein3.4.23.160.460
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.460
2xjjL81Heat shock protein HSP 90-alpha/0.460
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.460
3qtzX42Cyclin-dependent kinase 22.7.11.220.460
3rak03ZCyclin-dependent kinase 22.7.11.220.460
3upjU03Gag-Pol polyprotein/0.460
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.459
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.459
3dejRXCCaspase-33.4.22.560.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.459
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.459
4u8iFDAUDP-galactopyranose mutase/0.459
1jstATPCyclin-dependent kinase 22.7.11.220.458
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.458
2b7aIZATyrosine-protein kinase JAK2/0.458
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.458
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.458
3bi2FADPolyamine oxidase FMS1/0.458
3gbuATPUncharacterized sugar kinase PH14592.7.10.458
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
4jrvKJVEpidermal growth factor receptor2.7.10.10.458
2rh9IGPTryptophan synthase alpha chain/0.457
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.457
3ruvANPChaperonin/0.457
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.457
1gij2PUCyclin-dependent kinase 22.7.11.220.456
1lhvNOGSex hormone-binding globulin/0.456
1q3sADPThermosome subunit alpha/0.456
2c475IDCasein kinase I isoform gamma-2/0.456
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.456
2wouZZFTGF-beta receptor type-12.7.11.300.456
2ylrFADPhenylacetone monooxygenase1.14.13.920.456
3a1l2CCCytochrome P450/0.456
3bgxMEFThymidylate synthase/0.456
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
3i60E86Mitogen-activated protein kinase 12.7.11.240.456
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.456
3qtrX36Cyclin-dependent kinase 22.7.11.220.456
4a6cQG9Gag-Pol polyprotein3.4.23.160.456
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
1rk3VDXVitamin D3 receptor/0.455
2c27ACOMycothiol acetyltransferase2.3.1.1890.455
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.455
2ylxFADPhenylacetone monooxygenase1.14.13.920.455
3qxpX64Cyclin-dependent kinase 22.7.11.220.455
4g1y0VOVitamin D3 receptor A/0.455
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.455
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.455
4z24FADPutative GMC-type oxidoreductase R13510.455
1phhFADp-hydroxybenzoate hydroxylase/0.454
3oroAGSSerine/threonine protein kinase/0.454
4b1fKRHGlutamate racemase/0.454
4e2bFMNDehydrogenase/0.454
4l4xNDPAmphI/0.454
4upjU04Gag-Pol polyprotein/0.454
1f8sFADL-amino-acid oxidase1.4.3.20.453
1me6IVSPlasmepsin-23.4.23.390.453
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.453
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.453
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.453
2p4yC03Peroxisome proliferator-activated receptor gamma/0.453
2qnqQN3Gag-Pol polyprotein3.4.23.160.453
2wotZZGTGF-beta receptor type-12.7.11.300.453
3eem53VUncharacterized protein/0.453
3kddJZQGag-Pol polyprotein3.4.23.160.453
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4bb3KKAIsopenicillin N synthase1.21.3.10.453
4bcnT9NCyclin-dependent kinase 22.7.11.220.453
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.453
4ji91M3Tyrosine-protein kinase JAK2/0.453
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.453
3sn6P0GBeta-2 adrenergic receptor/0.453
2fznFADBifunctional protein PutA1.5.5.20.452
2q4bNAPUncharacterized protein At5g02240/0.452
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2vu3LZECyclin-dependent kinase 22.7.11.220.452
3bhlTHGThymidylate synthase/0.452
3ezvEZVCyclin-dependent kinase 22.7.11.220.452
3qu0X40Cyclin-dependent kinase 22.7.11.220.452
3vetADPnebramycin 5' synthase6.1.2.20.452
3zqaNDPNAD/NADP-dependent betaine aldehyde dehydrogenase/0.452
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.452
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.452
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4hvi19STyrosine-protein kinase JAK32.7.10.20.452
4knzCB3Thymidylate synthase/0.452
4qi5FADCellobiose dehydrogenase/0.452
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.452
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.452
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
2exmZIPCyclin-dependent kinase 22.7.11.220.451
2ou2ACOHistone acetyltransferase KAT5/0.451
2w4iVGAGlutamate racemase/0.451
2y9qANPMitogen-activated protein kinase 12.7.11.240.451
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.451
3axwTIDCasein kinase II subunit alpha2.7.11.10.451
3i6oGR6Gag-Pol polyprotein3.4.23.160.451
3orpAGSSerine/threonine protein kinase/0.451
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.451
4fnyI3KALK tyrosine kinase receptor2.7.10.10.451
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
1ivq0PXGag-Pol polyprotein/0.450
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1xq6NAPUncharacterized protein At5g02240/0.450
2b52D42Cyclin-dependent kinase 22.7.11.220.450
2ftoCB3Thymidylate synthase/0.450
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.450
2j4z626Aurora kinase A2.7.11.10.450
2jkkBI9Focal adhesion kinase 12.7.10.20.450
2pvlP55Casein kinase II subunit alpha2.7.11.10.450
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.450
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2x4f16XMyosin light chain kinase family member 42.7.11.10.450
3hllI45Mitogen-activated protein kinase 14/0.450
3iphG11Mitogen-activated protein kinase 14/0.450
3rjc06ZCyclin-dependent kinase 22.7.11.220.450
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.450
3w0c6DSVitamin D3 receptor/0.450
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
4dqb017Gag-Pol polyprotein/0.450
4hnf16WCasein kinase I isoform delta2.7.11.10.450
4njsG08Protease/0.450
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1ec0BEDGag-Pol polyprotein3.4.23.160.449
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1rjkVDZVitamin D3 receptor/0.449
1s6qTPBGag-Pol polyprotein2.7.7.490.449
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.449
2w17I19Cyclin-dependent kinase 22.7.11.220.449
2x7bCOAN-alpha-acetyltransferase2.3.10.449
3hub469Mitogen-activated protein kinase 14/0.449
3kfr3TLGag-Pol polyprotein/0.449
3l8xN4DMitogen-activated protein kinase 14/0.449
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.449
3ruqADPChaperonin/0.449
3uli1N3Cyclin-dependent kinase 22.7.11.220.449
3vfa031Gag-Pol polyprotein3.4.23.160.449
3wy0COAUncharacterized protein/0.449
4a62ANPPlasmid segregation protein ParM/0.449
4a99FADTetX family tetracycline inactivation enzyme/0.449
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.449
4gevCB3Thymidylate synthase/0.449
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.449
4kba1QMCasein kinase I isoform delta2.7.11.10.449
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.449
4n6bCOAUncharacterized protein/0.449
4n6hEJ4Delta-type opioid receptor/0.449
4xgiNADGlutamate dehydrogenase/0.449
1kifFADD-amino-acid oxidase1.4.3.30.448
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.448
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1yp4ADQGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.448
2aazCB3Thymidylate synthase2.1.1.450.448
2gqwFADFerredoxin reductase/0.448
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.448
2obyNAPQuinone oxidoreductase PIG310.448
2qi1MZ4Gag-Pol polyprotein/0.448
2ydoADNAdenosine receptor A2a/0.448
3adaNADSubunit alpha of sarocosine oxidase/0.448
4bcmT7ZCyclin-dependent kinase 22.7.11.220.448
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.448
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.448
4jbqVX6Aurora kinase A2.7.11.10.448
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.448
5f2kSAHUncharacterized protein/0.448
1bxsNADRetinal dehydrogenase 11.2.1.360.447
1nq24HYThyroid hormone receptor beta/0.447
1ppjANYCytochrome b/0.447
1uzwCDHIsopenicillin N synthase1.21.3.10.447
1w06W05Isopenicillin N synthase1.21.3.10.447
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
2psuMUUProtease/0.447
2qi3MZ5Gag-Pol polyprotein/0.447
3ekyDR7Gag-Pol polyprotein3.4.23.160.447
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.447
3o9dK19Pol polyprotein/0.447
3s2pPMUCyclin-dependent kinase 22.7.11.220.447
3tjsD0RCytochrome P450 3A4/0.447
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.447
4kb81QNCasein kinase I isoform delta2.7.11.10.447
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.447
4ntcFADThioredoxin reductase gliT/0.447
5f0a1FBcGMP-dependent protein kinase, putative/0.447
5iu4ZMAAdenosine receptor A2a/0.447
1hfqMOTDihydrofolate reductase1.5.1.30.446
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
1ju6LYAThymidylate synthase2.1.1.450.446
1pkdUCNCyclin-dependent kinase 22.7.11.220.446
1qvnFRIInterleukin-2/0.446
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.446
1w5vBE3Gag-Pol polyprotein3.4.23.160.446
1y0s331Peroxisome proliferator-activated receptor delta/0.446
2huvSAHDiphthine synthase/0.446
2itnANPEpidermal growth factor receptor2.7.10.10.446
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.446
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.446
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.446
3drcMTXDihydrofolate reductase1.5.1.30.446
3el1DR7Gag-Pol polyprotein3.4.23.160.446
3h9f92MDual specificity protein kinase TTK2.7.12.10.446
3kq7KQ7Mitogen-activated protein kinase 14/0.446
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.446
3rusADPChaperonin/0.446
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.446
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.446
4cdmFADDeoxyribodipyrimidine photolyase/0.446
4jk3NADUncharacterized protein/0.446
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.446
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.446
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.446
1meuDMPGag-Pol polyprotein3.4.23.160.445
1mtrPI6Gag-Pol polyprotein3.4.23.160.445
1oiyN41Cyclin-dependent kinase 22.7.11.220.445
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.445
1sx4ADP60 kDa chaperonin/0.445
2cjmATPCyclin-dependent kinase 22.7.11.220.445
2iviACWIsopenicillin N synthase1.21.3.10.445
2jn3JN3Fatty acid-binding protein, liver/0.445
2pym1UNGag-Pol polyprotein3.4.23.160.445
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.445
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.445
3k5uPFQAurora kinase A2.7.11.10.445
3kveFADL-amino-acid oxidase/0.445
3qqkX02Cyclin-dependent kinase 22.7.11.220.445
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.445
3w5p4OAVitamin D3 receptor/0.445
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fv9E71Mitogen-activated protein kinase 12.7.11.240.445
4g3sUD1Bifunctional protein GlmU/0.445
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4ii5ADPCyclin-dependent kinase 22.7.11.220.445
4q5hANPProtein kinase OspG2.70.445
4qi4FADCellobiose dehydrogenase/0.445
4yryFADGlutamate synthase, beta subunit/0.445
5br7FADUDP-galactopyranose mutase/0.445
1bdqIM1Gag-Pol polyprotein3.4.23.160.444
1bi9NADRetinal dehydrogenase 2/0.444
1c6yMK1Protease/0.444
1dajMOTDihydrofolate reductase1.5.1.30.444
1fwkADPHomoserine kinase2.7.1.390.444
1ie8KH1Vitamin D3 receptor/0.444
1j7lADPAminoglycoside 3'-phosphotransferase2.7.1.950.444
1osvCHCBile acid receptor/0.444
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1t7i017Gag-Pol polyprotein3.4.23.160.444
1xddAAYIntegrin alpha-L/0.444
1z1rHBHGag-Pol polyprotein3.4.23.160.444
2b55D31Cyclin-dependent kinase 22.7.11.220.444
2bpw1INGag-Pol polyprotein3.4.23.160.444
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.444
2ofv242Tyrosine-protein kinase Lck2.7.10.20.444
2p5yNADUDP-glucose 4-epimerase/0.444
2psvMUVProtease/0.444
2pvnP63Casein kinase II subunit alpha2.7.11.10.444
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.444
3bc3OPTCathepsin L13.4.22.150.444
3i0rRT3Gag-Pol polyprotein2.7.7.490.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3qtwX3ACyclin-dependent kinase 22.7.11.220.444
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
3vf2ADPnebramycin 5' synthase6.1.2.20.444
3vt7VDXVitamin D3 receptor/0.444
4ez50RSCyclin-dependent kinase 62.7.11.220.444
4fkj11KCyclin-dependent kinase 22.7.11.220.444
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.444
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.444
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.444
4nb6444Nuclear receptor ROR-gamma/0.444
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.444
4nu5NADPhosphonate dehydrogenase1.20.1.10.444
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.444
6upjNIUGag-Pol polyprotein/0.444
1gp2GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
1hwr216Gag-Pol polyprotein3.4.23.160.443
1ie9VDXVitamin D3 receptor/0.443
1kgjFL8Transthyretin/0.443
1kqdFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
1p0hACOMycothiol acetyltransferase2.3.1.1890.443
1rrmAPRLactaldehyde reductase1.1.1.770.443
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.443
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.443
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.443
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.443
2qa2FADPolyketide oxygenase CabE/0.443
2vbdV10Isopenicillin N synthase1.21.3.10.443
2vv9IM9Cyclin-dependent kinase 22.7.11.220.443
2wetFADTryptophan 5-halogenase/0.443
2xikJ60Serine/threonine-protein kinase 252.7.11.10.443
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.443
3b70NAPEnoyl reductase LovC10.443
3itjFADThioredoxin reductase 11.8.1.90.443
3lu7IPXSerum albumin/0.443
3m7rVDXVitamin D3 receptor/0.443
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.443
3pyy3YYTyrosine-protein kinase ABL12.7.10.20.443
4h4sFADBiphenyl dioxygenase ferredoxin reductase subunit/0.443
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.443
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
1mrxK57Gag-Pol polyprotein3.4.23.160.442
1ojtFADDihydrolipoyl dehydrogenase/0.442
1pxmCK5Cyclin-dependent kinase 22.7.11.220.442
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.442
2jt2C90UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.442
2qk8MTXDihydrofolate reductase/0.442
2vkeTACTetracycline repressor protein class D/0.442
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.442
3ec0GRLGag-Pol polyprotein3.4.23.470.442
3gxlQIGTGF-beta receptor type-12.7.11.300.442
3i2l2NCProtease/0.442
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.442
3p6oETGCamphor 5-monooxygenase1.14.15.10.442
3t2kFADSulfide-quinone reductase/0.442
3uleC69Actin-related protein 3/0.442
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.442
3uvp048Mitogen-activated protein kinase 14/0.442
3vt5YI2Vitamin D3 receptor/0.442
4aguD15Cyclin-dependent kinase-like 1/0.442
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4bvaT3Ketimine reductase mu-crystallin1.5.1.250.442
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.442
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.442
4jqeANPCasein kinase II subunit alpha2.7.11.10.442
4pkl1GHUncharacterized protein/0.442
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
4ug2NGIAdenosine receptor A2a/0.442
1a8pFADFerredoxin--NADP reductase/0.441
1hpv478Gag-Pol polyprotein/0.441
1ipeNDPTropinone reductase 21.1.1.2360.441
1jujLYAThymidylate synthase2.1.1.450.441
1ke5LS1Cyclin-dependent kinase 22.7.11.220.441
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
1wn3HXCPhenylacetic acid degradation protein PaaI/0.441
2e20B4PPropionate kinase/0.441
2eufLQQCyclin-dependent kinase 62.7.11.220.441
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.441
2hm9TRRDihydrofolate reductase1.5.1.30.441
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.441
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.441
2p2xSAHDiphthine synthase/0.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2vnaNAPProstaglandin reductase 21.3.1.480.441
2vttLZDCyclin-dependent kinase 22.7.11.220.441
2ze2T27Gag-Pol polyprotein2.7.7.490.441
2znpK55Peroxisome proliferator-activated receptor delta/0.441
3atzFMNProstaglandin F2a synthase/0.441
3cbsR12Cellular retinoic acid-binding protein 2/0.441
3fhyATPPyridoxal kinase2.7.1.350.441
3gy0NAPNAD(P)-dependent oxidoreductase/0.441
3mxdK53Gag-Pol polyprotein3.4.23.160.441
3o9hK2EGag-Pol polyprotein/0.441
3rf7NADIron-containing alcohol dehydrogenase/0.441
3rpr25ZCyclin-dependent kinase 22.7.11.220.441
3s4qNK0Mitogen-activated protein kinase 14/0.441
3vquO22Dual specificity protein kinase TTK2.7.12.10.441
4b3aTACTetracycline repressor protein class D/0.441
4cryACOPanD regulatory factor/0.441
4dqh017Gag-Pol polyprotein/0.441
4h4tFADBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4xpdACON-terminal acetyltransferase A complex subunit NAT52.3.10.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.441
9hvp0E9Gag-Pol polyprotein/0.441
1b6mPI6Gag-Pol polyprotein3.4.23.160.440
1drhNAPDihydrofolate reductase1.5.1.30.440
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.440
1kzjCB3Thymidylate synthase/0.440
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.440
1pdhFASp-hydroxybenzoate hydroxylase/0.440
1pxpCK8Cyclin-dependent kinase 22.7.11.220.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
1svmATPLarge T antigen3.6.40.440
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.440
2cvjFADThioredoxin reductase related protein/0.440
2d1tSLULuciferin 4-monooxygenase1.13.12.70.440
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.440
2gr1FADFerredoxin reductase/0.440
2qi0MZ3Gag-Pol polyprotein/0.440
2qi6MZ8Gag-Pol polyprotein/0.440
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.440
2vbpVB1Isopenicillin N synthase1.21.3.10.440
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.440
2y0mACOHistone acetyltransferase KAT8/0.440
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.440
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.440
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.440
3aw9NADNAD-dependent epimerase/dehydratase/0.440
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.440
3fmkFMKMitogen-activated protein kinase 14/0.440
3nux3NVCyclin-dependent kinase 62.7.11.220.440
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
3qzgX67Cyclin-dependent kinase 22.7.11.220.440
3rpv26ZCyclin-dependent kinase 22.7.11.220.440
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
3u9eCOALmo1369 protein/0.440
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
3uwlFOZThymidylate synthase/0.440
3v3m0ENReplicase polyprotein 1a3.4.19.120.440
3vtbTKAVitamin D3 receptor/0.440
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.440
3w33W19Epidermal growth factor receptor2.7.10.10.440
4b8uIBK3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.440
4brxKGWFocal adhesion kinase 12.7.10.20.440
4dymIYZActivin receptor type-12.7.11.300.440
4hgt15GCasein kinase I isoform delta2.7.11.10.440
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
4l2oNADAldehyde dehydrogenase, dimeric NADP-preferring/0.440
4okx198Androgen receptor/0.440
4u8nFDAUDP-galactopyranose mutase/0.440
5fknTDCTetracycline repressor protein class D/0.440