sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5hpy | GDP | Transforming protein RhoA |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5hpy | GDP | Transforming protein RhoA | / | 1.000 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.509 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.508 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.502 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.502 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.496 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.494 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.493 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.490 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.483 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.482 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.481 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.479 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.476 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.475 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.471 | |
| 4mit | GTP | Rho-related protein racC | / | 0.471 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.469 | |
| 4oi2 | ADP | Protein clpf-1 | / | 0.466 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.464 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.459 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.457 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.455 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.455 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.455 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.455 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.454 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.453 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.451 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.448 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.446 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.446 | |
| 4nyj | GNP | GTPase HRas | / | 0.446 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.445 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.445 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.444 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.443 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.443 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.443 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.443 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.441 |