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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5h841VUHistone acetyltransferase KAT2A2.3.1.48

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5h841VUHistone acetyltransferase KAT2A2.3.1.481.000
1z4rACOHistone acetyltransferase KAT2A2.3.1.480.699
5h86BCOHistone acetyltransferase KAT2A2.3.1.480.592
1qsrACOHAT A1/0.525
1cm0COAHistone acetyltransferase KAT2B2.3.1.480.503
1cjwCOTSerotonin N-acetyltransferase/0.449
2jddACOProbable acetyltransferase/0.448