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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5fuwTHMThymidine kinase, putative

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5fuwTHMThymidine kinase, putative/1.000
5fuvTHMThymidine kinase, putative/0.541
2b8tTHMThymidine kinase/0.540
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.454
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.453
3tgyASCLactoperoxidase1.11.1.70.451
4fvz4KJNitric oxide synthase, brain1.14.13.390.448
2z3uCRRCytochrome P450/0.446
3oqkS52Renin3.4.23.150.444
3qfrFMNNADPH--cytochrome P450 reductase/0.444
1pqc444Oxysterols receptor LXR-beta/0.441
3isjA8DPantothenate synthetase6.3.2.10.441
3ebf332Nitric oxide synthase, inducible1.14.13.390.440