sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 1.000 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.597 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.587 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.553 | |
| 4h4s | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.547 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.541 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.540 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.535 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.535 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.529 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.506 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.503 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.495 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.494 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.473 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.470 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.468 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.467 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.465 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.456 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.440 |