sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fli | QUE | Quercetinase QueD |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5fli | QUE | Quercetinase QueD | / | 1.000 | |
| 5flj | QUE | Quercetinase QueD | / | 0.575 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.477 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.470 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.467 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.464 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.462 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.460 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.458 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.457 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.457 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.453 | |
| 3nfr | EWQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 3nju | ANN | Acidic phospholipase A2 3 | 3.1.1.4 | 0.451 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.449 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.448 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.447 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.447 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.445 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.444 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1s36 | CEI | Obelin | / | 0.442 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.442 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.442 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.442 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 4kxj | P34 | Nucleoprotein | / | 0.442 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.442 | |
| 3c1o | NAP | Eugenol synthase | / | 0.441 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.440 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.440 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |