scPDB - Distribution of Binding site Similarity values of 5fa8 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5fa8	SAM	Ribosomal protein L11 methyltransferase, putative

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5fa8	SAM	Ribosomal protein L11 methyltransferase, putative	/	1.000
2b9w	FAD	Putative aminooxidase	/	0.492
3dej	RXC	Caspase-3	3.4.22.56	0.487
2yx1	SFG	tRNA (guanine(37)-N1)-methyltransferase Trm5b	2.1.1.228	0.484
2eg5	SAH	7-methylxanthosine synthase 1	/	0.478
4m37	SAH	Protein arginine N-methyltransferase 7	2.1.1	0.477
2ih2	NEA	Modification methylase TaqI	2.1.1.72	0.474
3ibd	CPZ	Cytochrome P450 2B6	1.14.13	0.473
1g38	NEA	Modification methylase TaqI	2.1.1.72	0.471
2np7	NEA	Modification methylase TaqI	2.1.1.72	0.470
4ekg	0QJ	Histone-lysine N-methyltransferase, H3 lysine-79 specific	2.1.1.43	0.468
4uy6	SAH	Histidine N-alpha-methyltransferase	/	0.467
1nv8	SAM	Release factor glutamine methyltransferase	2.1.1.297	0.465
3tm5	SFG	Uncharacterized protein	/	0.465
1nw3	SAM	Histone-lysine N-methyltransferase, H3 lysine-79 specific	2.1.1.43	0.464
2qbm	CAM	Camphor 5-monooxygenase	1.14.15.1	0.464
1nv9	SAH	Release factor glutamine methyltransferase	2.1.1.297	0.463
3sr4	TT8	Histone-lysine N-methyltransferase, H3 lysine-79 specific	2.1.1.43	0.463
5e72	SAM	N2, N2-dimethylguanosine tRNA methyltransferase	/	0.462
2q8s	L92	Peroxisome proliferator-activated receptor gamma	/	0.460
3ldf	SAH	Uncharacterized protein	/	0.460
3s1s	SAH	Restriction endonuclease BpuSI	/	0.459
3tk3	CPZ	Cytochrome P450 2B4	1.14.14.1	0.459
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.458
1nw5	SAM	Modification methylase RsrI	2.1.1.72	0.457
1sg9	SAM	Release factor glutamine methyltransferase	2.1.1.297	0.457
5bxy	SAH	Putative RNA methylase family UPF0020	/	0.457
5e8j	SAH	mRNA cap guanine-N7 methyltransferase	2.1.1.56	0.456
1svg	I04	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.455
1wy7	SAH	Uncharacterized protein	/	0.455
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.455
1knu	YPA	Peroxisome proliferator-activated receptor gamma	/	0.454
1s0x	C3S	Nuclear receptor ROR-alpha	/	0.453
3egv	SAH	Ribosomal protein L11 methyltransferase	2.1.1	0.452
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.452
1j4j	ACO	Acetyltransferase	2.3.1	0.450
1ie9	VDX	Vitamin D3 receptor	/	0.449
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.449
4a4w	YFB	Peroxisome proliferator-activated receptor gamma	/	0.449
4gol	SA8	DNA adenine methylase	2.1.1.72	0.449
4jhz	1KV	Beta-glucuronidase	3.2.1.31	0.449
4v2g	ITC	Tetracycline repressor protein class D	/	0.449
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.448
1j7u	ANP	Aminoglycoside 3'-phosphotransferase	2.7.1.95	0.448
2ba9	FAD	Putative aminooxidase	/	0.448
3vt3	VDX	Vitamin D3 receptor	/	0.448
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
4rto	SFG	DNA adenine methylase	2.1.1.72	0.448
1geu	FAD	Glutathione reductase	1.8.1.7	0.447
1suo	CPZ	Cytochrome P450 2B4	1.14.14.1	0.447
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.447
3a25	SAM	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase	/	0.446
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.446
3pt9	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.446
3w5p	4OA	Vitamin D3 receptor	/	0.445
4h0n	SAH	Dnmt2	/	0.445
1fdt	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.444
2g82	NAD	Glyceraldehyde-3-phosphate dehydrogenase	/	0.444
3vso	EK1	Peroxisome proliferator-activated receptor gamma	/	0.444
1i7i	AZ2	Peroxisome proliferator-activated receptor gamma	/	0.443
1q8u	H52	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.443
2b9x	FAD	Putative aminooxidase	/	0.443
3t3r	9PL	Cytochrome P450 2A6	1.14.13	0.443
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.443
4q72	FAD	Bifunctional protein PutA	/	0.443
4qpp	SAH	Protein arginine N-methyltransferase 6	/	0.443
1nyx	DRF	Peroxisome proliferator-activated receptor gamma	/	0.442
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.442
2om9	AJA	Peroxisome proliferator-activated receptor gamma	/	0.442
2qtc	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.442
2xck	MH4	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.442
2zif	SAM	Methyltransferase	/	0.442
1k6t	XN1	Gag-Pol polyprotein	3.4.23.16	0.441
1vzb	UMP	Thymidylate synthase	/	0.441
2f7x	4EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
4amb	DUD	Putative glycosyl transferase	/	0.441
4onq	SFG	DNA methyltransferase	/	0.441
4uym	VOR	14-alpha sterol demethylase Cyp51B	/	0.441
2iya	ZIO	Oleandomycin glycosyltransferase	/	0.440
3bl7	DD1	m7GpppX diphosphatase	3.6.1.59	0.440
3swr	SFG	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.440
3vsp	EK8	Peroxisome proliferator-activated receptor gamma	/	0.440
3wmx	NAD	NAD dependent epimerase/dehydratase	/	0.440
4rtp	SAM	DNA adenine methylase	2.1.1.72	0.440
4ruj	VDX	Vitamin D3 receptor A	/	0.440
5f2k	SAH	Uncharacterized protein	/	0.440