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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5f8uP32Beta-1 adrenergic receptor

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5f8uP32Beta-1 adrenergic receptor/1.000
2ycxP32Beta-1 adrenergic receptor/0.601
2ycyP32Beta-1 adrenergic receptor/0.594
2yczI32Beta-1 adrenergic receptor/0.592
4amjCVDBeta-1 adrenergic receptor/0.588
5d6lCAUBeta-2 adrenergic receptor/0.588
2rh1CAUBeta-2 adrenergic receptor/0.584
5d5aCAUBeta-2 adrenergic receptor/0.579
4gbrCAUBeta-2 adrenergic receptor/0.579
2y035FWBeta-1 adrenergic receptor/0.571
2ycwCAUBeta-1 adrenergic receptor/0.571
3ny9JSZBeta-2 adrenergic receptor/0.567
4amiG90Beta-1 adrenergic receptor/0.550
5d5bCAUBeta-2 adrenergic receptor/0.545
5jqhCAUBeta-2 adrenergic receptor/0.543
2y01Y00Beta-1 adrenergic receptor/0.533
4bvnP32Beta-1 adrenergic receptor/0.533
2y0468HBeta-1 adrenergic receptor/0.531
3zpqXF5Beta-1 adrenergic receptor/0.515
3nyaJTZBeta-2 adrenergic receptor/0.511
5a8eXTKBeta-1 adrenergic receptor/0.510
2vt4P32Beta-1 adrenergic receptor/0.509
3ny8JRZBeta-2 adrenergic receptor/0.506
3d4sTIMBeta-2 adrenergic receptor/0.500
2y02WHJBeta-1 adrenergic receptor/0.481
4ldeP0GBeta-2 adrenergic receptor/0.474
4iarERM5-hydroxytryptamine receptor 1B/0.448
5fd8A5APutative carboxypeptidase yocD/0.443