Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5eyuNADBetaine-aldehyde dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5eyuNADBetaine-aldehyde dehydrogenase/1.000
4pt0NADAldehyde dehydrogenase/0.476
2onpNADAldehyde dehydrogenase, mitochondrial1.2.1.30.472
4fr8NADAldehyde dehydrogenase, mitochondrial1.2.1.30.466
1o02NADAldehyde dehydrogenase, mitochondrial1.2.1.30.465
3iwkNADAminoaldehyde dehydrogenase/0.462
2j40NAD1-pyrroline-5-carboxylate dehydrogenase/0.459
1o00NADAldehyde dehydrogenase, mitochondrial1.2.1.30.455
3n82NADAldehyde dehydrogenase, mitochondrial1.2.1.30.455
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.454
2j5nNAD1-pyrroline-5-carboxylate dehydrogenase/0.452
4v37NADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.451
1nzzNAIAldehyde dehydrogenase, mitochondrial1.2.1.30.446
4f3xNADPutative aldehyde dehydrogenase/0.444
1nzwNAIAldehyde dehydrogenase, mitochondrial1.2.1.30.443
2eiiNAD1-pyrroline-5-carboxylate dehydrogenase/0.443
2ehqNAP1-pyrroline-5-carboxylate dehydrogenase/0.442
4i1wNAD2-aminomuconate 6-semialdehyde dehydrogenase/0.442
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.440