sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ebu | FMN | Lactate oxidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5ebu | FMN | Lactate oxidase | / | 1.000 | |
| 2e77 | FMN | Lactate oxidase | / | 0.662 | |
| 2j6x | FMN | Lactate oxidase | / | 0.641 | |
| 4rje | FNR | Lactate oxidase | / | 0.603 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.600 | |
| 2nli | FMN | Lactate oxidase | / | 0.594 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.590 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.587 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.576 | |
| 2du2 | FMN | Lactate oxidase | / | 0.575 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.572 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.572 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.557 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.549 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.521 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.521 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.520 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.518 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.516 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.511 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.510 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.507 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.504 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.504 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.500 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.499 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.499 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.498 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.498 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.497 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.497 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.495 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.494 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.487 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.486 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.485 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.485 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.485 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 4jic | FMN | GTN Reductase | / | 0.484 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.484 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.483 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.482 | |
| 2zfa | FMN | Lactate oxidase | / | 0.481 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.481 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.480 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.480 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.479 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.479 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 4e2b | FMN | Dehydrogenase | / | 0.479 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.478 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.477 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.476 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.476 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.476 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.476 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.475 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.475 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.474 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.473 | |
| 3hf3 | FMN | Chromate reductase | / | 0.473 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.472 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.472 | |
| 4utk | FNR | Xenobiotic reductase | / | 0.472 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.471 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.471 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.471 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.470 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.470 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.469 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.469 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.469 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.469 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.468 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.468 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.468 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.467 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.466 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.465 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.465 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.464 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.464 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.464 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 4z38 | FMN | MlnA | / | 0.464 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.463 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.463 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.463 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.463 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.462 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.462 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.462 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.462 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.462 | |
| 4oag | ADP | Mitochondrial dynamics protein MID51 | / | 0.462 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.461 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.461 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.461 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.461 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.460 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.460 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.460 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.460 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.460 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.459 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.458 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.458 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.458 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.458 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.458 | |
| 1vza | UMP | Thymidylate synthase | / | 0.457 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.457 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.457 | |
| 4iae | 1DX | Alr2278 protein | / | 0.457 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.456 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.456 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.456 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.455 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.455 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.455 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 4e2d | FMN | Dehydrogenase | / | 0.455 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.455 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.455 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.454 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.454 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.453 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.453 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.452 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.452 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.451 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.451 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.451 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.451 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.451 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.451 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.451 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.451 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.450 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.450 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.450 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.450 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.450 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.450 | |
| 3v2u | ATP | Protein GAL3 | / | 0.450 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.450 | |
| 4lut | DCS | Alanine racemase | / | 0.450 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1ea0 | FMN | Glutamate synthase [NADPH] large chain | 1.4.1.13 | 0.449 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.449 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.449 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.449 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.449 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.449 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.449 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.448 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.448 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.448 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.448 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.448 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.448 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.447 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 2hay | FMN | Putative NAD(P)H-flavin oxidoreductase | / | 0.447 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.447 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.447 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.447 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.446 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.446 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.446 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.446 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.446 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.446 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.445 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.445 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.445 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.445 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.445 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.445 | |
| 3dh8 | B4N | Uncharacterized protein PA1000 | / | 0.445 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.445 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.445 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.445 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.445 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.445 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.445 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.444 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.444 | |
| 2fna | ADP | Uncharacterized protein | / | 0.444 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.444 | |
| 2xw1 | 9NV | Serum albumin | / | 0.444 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.444 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.443 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.443 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.443 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.443 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.443 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.443 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.443 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.442 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.442 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.442 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.442 | |
| 3e6y | CW1 | 14-3-3-like protein C | / | 0.442 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.442 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.442 | |
| 3x2u | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.442 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.442 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.442 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.442 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.441 | |
| 2o12 | FMN | Chorismate synthase | / | 0.441 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.441 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.441 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.441 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.441 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3cvu | FAD | RE11660p | / | 0.440 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.440 |