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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5e92ANPTGF-beta receptor type-22.7.11.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5e92ANPTGF-beta receptor type-22.7.11.301.000
5e8ySTUTGF-beta receptor type-22.7.11.300.582
4k33ACPFibroblast growth factor receptor 32.7.10.10.553
4hge15VTyrosine-protein kinase JAK2/0.547
4qnyANPMitogen activated protein kinase, putative/0.545
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.540
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.536
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.529
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.526
4dymIYZActivin receptor type-12.7.11.300.523
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.522
3mtfA3FActivin receptor type-12.7.11.300.521
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.520
3i60E86Mitogen-activated protein kinase 12.7.11.240.518
3oom507Activin receptor type-12.7.11.300.517
5e8xSTUTGF-beta receptor type-12.7.11.300.517
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.515
1jnkANPMitogen-activated protein kinase 102.7.11.240.513
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.513
1u54ACPActivated CDC42 kinase 1/0.512
5cnnANPEpidermal growth factor receptor2.7.10.10.512
4bgg844Activin receptor type-12.7.11.300.511
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.510
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.510
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.510
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.508
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.508
3ttjJBIMitogen-activated protein kinase 102.7.11.240.508
3gu83GUDeath-associated protein kinase 12.7.11.10.506
4fmqANPMitogen-activated protein kinase 12.7.11.240.506
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.505
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.501
1rw8580TGF-beta receptor type-12.7.11.300.501
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.500
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.500
2y9qANPMitogen-activated protein kinase 12.7.11.240.500
3eljGS7Mitogen-activated protein kinase 82.7.11.240.500
4aqc88ATyrosine-protein kinase JAK2/0.499
5e8wSTUTGF-beta receptor type-12.7.11.300.498
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.497
4h3qANPMitogen-activated protein kinase 12.7.11.240.497
1bygSTUTyrosine-protein kinase CSK/0.496
1dayGNPCasein kinase II subunit alpha2.7.11.10.496
3rvg17PTyrosine-protein kinase JAK2/0.496
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.495
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.495
4c58824Cyclin-G-associated kinase2.7.11.10.494
4fv6E57Mitogen-activated protein kinase 12.7.11.240.494
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.492
2p33J07Mitogen-activated protein kinase 102.7.11.240.492
5drdATPAurora kinase A2.7.11.10.491
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
3nieANPMitogen-activated protein kinase/0.490
4btjATPTau-tubulin kinase 12.7.11.10.490
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.489
4gk2L66Ephrin type-A receptor 32.7.10.10.489
4j95ACPFibroblast growth factor receptor 2/0.489
1oiyN41Cyclin-dependent kinase 22.7.11.220.488
2pmlANPUncharacterized protein/0.488
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.488
4nifANPMitogen-activated protein kinase 12.7.11.240.488
3hmm855TGF-beta receptor type-12.7.11.300.487
1pmn984Mitogen-activated protein kinase 102.7.11.240.485
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.485
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.485
4c57FEFCyclin-G-associated kinase2.7.11.10.485
4hvi19STyrosine-protein kinase JAK32.7.10.20.485
4jia1K3Tyrosine-protein kinase JAK2/0.485
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.485
1ol5ADPAurora kinase A2.7.11.10.484
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.484
2henADPEphrin type-B receptor 22.7.10.10.484
3cgfJNFMitogen-activated protein kinase 102.7.11.240.484
3gxlQIGTGF-beta receptor type-12.7.11.300.484
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.484
4jrnANPRhoptry kinase family protein/0.484
1py5PY1TGF-beta receptor type-12.7.11.300.483
2wotZZGTGF-beta receptor type-12.7.11.300.483
4e6d0NUTyrosine-protein kinase JAK2/0.483
4gk3L87Ephrin type-A receptor 32.7.10.10.483
4lfiGNPCasein kinase II subunit alpha2.7.11.10.483
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.483
4zseANPEpidermal growth factor receptor2.7.10.10.483
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.482
3gubGUBDeath-associated protein kinase 12.7.11.10.482
5eg3ACPFibroblast growth factor receptor 2/0.482
2hckQUETyrosine-protein kinase HCK2.7.10.20.481
4btjADPTau-tubulin kinase 12.7.11.10.481
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.481
4gk4L90Ephrin type-A receptor 32.7.10.10.481
4o1pANPRibonuclease L/0.481
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.480
4ivb1J5Tyrosine-protein kinase JAK1/0.480
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.480
5cnoANPEpidermal growth factor receptor2.7.10.10.480
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.479
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.479
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.478
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.478
3clyACPFibroblast growth factor receptor 2/0.478
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.478
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.478
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.478
3t8oATPRhodopsin kinase/0.477
4fkv61KCyclin-dependent kinase 22.7.11.220.477
3oriAGSSerine/threonine protein kinase/0.476
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.476
4deeADPAurora kinase A2.7.11.10.476
4fv9E71Mitogen-activated protein kinase 12.7.11.240.476
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.475
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.475
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.475
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.474
2uzbC75Cyclin-dependent kinase 22.7.11.220.474
4jr7GNPCasein kinase II subunit alpha2.7.11.10.474
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.474
1qmzATPCyclin-dependent kinase 22.7.11.220.473
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.473
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.473
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.473
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.473
2qo7ANPEphrin type-A receptor 32.7.10.10.473
2zdt46CMitogen-activated protein kinase 102.7.11.240.473
3gu7ADPDeath-associated protein kinase 12.7.11.10.473
3zdu38RCyclin-dependent kinase-like 32.7.11.220.473
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.473
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.473
5dt4ATPAurora kinase A2.7.11.10.473
3rmf20ZCyclin-dependent kinase 22.7.11.220.472
3tdvGDPGentamicin resistance protein/0.472
5dt3ATPAurora kinase A2.7.11.10.472
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2xrwANPMitogen-activated protein kinase 82.7.11.240.471
4c02TAKActivin receptor type-12.7.11.300.471
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.470
1zrzBI1Protein kinase C iota type2.7.11.130.470
3iok1P6Tyrosine-protein kinase JAK2/0.470
3zewSTUEphrin type-B receptor 42.7.10.10.470
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.470
4fvqATPTyrosine-protein kinase JAK2/0.470
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.469
2xvdAS6Ephrin type-B receptor 42.7.10.10.469
3be9P04Casein kinase II subunit alpha2.7.11.10.469
3orkAGSSerine/threonine protein kinase/0.469
3sheI85MAP kinase-activated protein kinase 32.7.11.10.469
4j99ACPFibroblast growth factor receptor 2/0.469
4wsqKSAAP2-associated protein kinase 12.7.11.10.469
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.468
1vjy460TGF-beta receptor type-12.7.11.300.468
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.468
4eol1ROCyclin-dependent kinase 22.7.11.220.468
4fv7E94Mitogen-activated protein kinase 12.7.11.240.468
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.468
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.468
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.467
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.467
3rak03ZCyclin-dependent kinase 22.7.11.220.467
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4ek816KCyclin-dependent kinase 22.7.11.220.467
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.467
4ysjADPCalmodulin-like domain protein kinase/0.467
5awmANPStress-activated protein kinase JNK2.7.11.240.467
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.466
2pz5ACPFibroblast growth factor receptor 2/0.466
2qoqANPEphrin type-A receptor 32.7.10.10.466
3gu6ADPDeath-associated protein kinase 12.7.11.10.466
3kvxFMYMitogen-activated protein kinase 102.7.11.240.466
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.466
1oitHDTCyclin-dependent kinase 22.7.11.220.465
2b7aIZATyrosine-protein kinase JAK2/0.465
2pvhP19Casein kinase II subunit alpha2.7.11.10.465
2py3ACPFibroblast growth factor receptor 2/0.465
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.465
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.465
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.465
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.464
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.464
2fvdLIACyclin-dependent kinase 22.7.11.220.464
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.464
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.464
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.464
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.464
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.464
4ux9ANPMitogen-activated protein kinase 82.7.11.240.464
1h1r6CPCyclin-dependent kinase 22.7.11.220.463
2pd7FADVivid PAS protein VVD/0.463
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.463
3s1dZIRCytokinin dehydrogenase 11.5.99.120.463
3zls92PDual specificity mitogen-activated protein kinase kinase 12.7.12.20.463
4ii5ADPCyclin-dependent kinase 22.7.11.220.463
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.463
4riyADPEpidermal growth factor receptor2.7.10.10.463
5av2KMPDeath-associated protein kinase 12.7.11.10.463
2pvmP29Casein kinase II subunit alpha2.7.11.10.462
2w06FRVCyclin-dependent kinase 22.7.11.220.462
3c4zADPRhodopsin kinase/0.462
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.462
3zh8C58Protein kinase C iota type2.7.11.130.462
3zmmF9JTyrosine-protein kinase JAK2/0.462
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.462
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
5dnrATPAurora kinase A2.7.11.10.462
1wvySTUDeath-associated protein kinase 12.7.11.10.461
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.461
2zdu446Mitogen-activated protein kinase 102.7.11.240.461
3lpbNVBTyrosine-protein kinase JAK2/0.461
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.461
4cegADPAurora kinase A2.7.11.10.461
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.461
4qmpDKISerine/threonine-protein kinase 242.7.11.10.461
1csnATPCasein kinase I homolog 12.7.11.10.460
1yvj4STTyrosine-protein kinase JAK32.7.10.20.460
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.460
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.460
2xs0ANPMitogen-activated protein kinase 82.7.11.240.460
3oroAGSSerine/threonine protein kinase/0.460
3qc9ADPRhodopsin kinase/0.460
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.460
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.460
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.460
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.460
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.460
5dn3ATPAurora kinase A2.7.11.10.460
1jpaANPEphrin type-B receptor 22.7.10.10.459
1lp4ANPCasein kinase II subunit alpha2.7.11.10.459
1om1IQACasein kinase II subunit alpha2.7.11.10.459
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.459
2j0lANPFocal adhesion kinase 12.7.10.20.459
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.459
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.459
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.459
4i5cC5ITyrosine-protein kinase JAK1/0.459
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.459
1dawANPCasein kinase II subunit alpha2.7.11.10.458
1u4dDBQActivated CDC42 kinase 1/0.458
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.458
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.458
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.458
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.458
4ji91M3Tyrosine-protein kinase JAK2/0.458
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.458
1jklANPDeath-associated protein kinase 12.7.11.10.457
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1p2a5BNCyclin-dependent kinase 22.7.11.220.457
1pmv537Mitogen-activated protein kinase 102.7.11.240.457
2hog710Serine/threonine-protein kinase Chk12.7.11.10.457
2o0uC0MMitogen-activated protein kinase 102.7.11.240.457
2xa4AZ5Tyrosine-protein kinase JAK2/0.457
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.457
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.457
1tvoFRZMitogen-activated protein kinase 12.7.11.240.456
2c27ACOMycothiol acetyltransferase2.3.1.1890.456
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.456
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.456
2y6o1N1Ephrin type-A receptor 42.7.10.10.456
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.456
3rpo24ZCyclin-dependent kinase 22.7.11.220.456
3sw418KCyclin-dependent kinase 22.7.11.220.456
1pxmCK5Cyclin-dependent kinase 22.7.11.220.455
2bhhRYUCyclin-dependent kinase 22.7.11.220.455
2pvnP63Casein kinase II subunit alpha2.7.11.10.455
2w4jADPDeath-associated protein kinase 12.7.11.10.455
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.455
3pe2E1BCasein kinase II subunit alpha2.7.11.10.455
3r71X86Cyclin-dependent kinase 22.7.11.220.455
3s1h56ZCyclin-dependent kinase 22.7.11.220.455
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.455
4fkw62KCyclin-dependent kinase 22.7.11.220.455
3wfjNAD2-dehydropantoate 2-reductase/0.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4ehzJAKTyrosine-protein kinase JAK1/0.454
4jboWPHAurora kinase A2.7.11.10.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.453
1e9hINRCyclin-dependent kinase 22.7.11.220.453
1ir3ANPInsulin receptor2.7.10.10.453
2c5yMTWCyclin-dependent kinase 22.7.11.220.453
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.453
2pzpACPFibroblast growth factor receptor 2/0.453
2x1nX1NCyclin-dependent kinase 22.7.11.220.453
3dogNNNCyclin-dependent kinase 22.7.11.220.453
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.453
4g2fC07Ephrin type-A receptor 32.7.10.10.453
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.453
4qmlANPSerine/threonine-protein kinase 242.7.11.10.453
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
3cgoJNOMitogen-activated protein kinase 102.7.11.240.452
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.452
3r8vZ62Cyclin-dependent kinase 22.7.11.220.452
4utdACPAurora kinase A2.7.11.10.452
2excJNKMitogen-activated protein kinase 102.7.11.240.451
2np8CC3Aurora kinase A2.7.11.10.451
2vwu7X1Ephrin type-B receptor 42.7.10.10.451
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.451
3el51UNGag-Pol polyprotein/0.451
3qtxX43Cyclin-dependent kinase 22.7.11.220.451
4f081RSTyrosine-protein kinase JAK2/0.451
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.450
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.450
2xneASHAurora kinase A2.7.11.10.450
3ggfGVDSerine/threonine-protein kinase 26/0.450
3r9dX6BCyclin-dependent kinase 22.7.11.220.450
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4j97ACPFibroblast growth factor receptor 2/0.450
4s33ANPMitogen-activated protein kinase 12.7.11.240.450
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.449
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.449
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.449
2pwlACPFibroblast growth factor receptor 2/0.449
2wouZZFTGF-beta receptor type-12.7.11.300.449
3d7tSTUTyrosine-protein kinase CSK/0.449
3ttiKBIMitogen-activated protein kinase 102.7.11.240.449
1ol7ADPAurora kinase A2.7.11.10.448
2b1pAIZMitogen-activated protein kinase 102.7.11.240.448
2c6iDT1Cyclin-dependent kinase 22.7.11.220.448
2h96893Mitogen-activated protein kinase 82.7.11.240.448
3bi6396Wee1-like protein kinase2.7.10.20.448
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.448
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3ormAGSSerine/threonine protein kinase/0.448
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.448
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.448
4jbqVX6Aurora kinase A2.7.11.10.448
4ki8ADP60 kDa chaperonin/0.448
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.448
4y93746Tyrosine-protein kinase/0.448
1b38ATPCyclin-dependent kinase 22.7.11.220.447
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1m2pHNACasein kinase II subunit alpha2.7.11.10.447
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.447
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.447
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2qocANPEphrin type-A receptor 32.7.10.10.447
3rk708ZCyclin-dependent kinase 22.7.11.220.447
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.447
3vryB43Tyrosine-protein kinase HCK2.7.10.20.447
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.447
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.447
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
5dr2ATPAurora kinase A2.7.11.10.447
1pf9ADP60 kDa chaperonin/0.446
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.446
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.446
2qo9ANPEphrin type-A receptor 32.7.10.10.446
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3ddqRRCCyclin-dependent kinase 22.7.11.220.446
3l8p0CEAngiopoietin-1 receptor2.7.10.10.446
3qu0X40Cyclin-dependent kinase 22.7.11.220.446
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.446
4ivd15TTyrosine-protein kinase JAK1/0.446
4lrjANPUncharacterized protein/0.446
1bwsNDPGDP-L-fucose synthase/0.445
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.445
3lltANPProtein serine/threonine kinase-1/0.445
3my5RFZCyclin-dependent kinase 22.7.11.220.445
3nbvANPKetohexokinase/0.445
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.445
3w32W32Epidermal growth factor receptor2.7.10.10.445
4acm7YGCyclin-dependent kinase 22.7.11.220.445
4b7xNAPProbable oxidoreductase/0.445
4eos1ROCyclin-dependent kinase 22.7.11.220.445
4i22IREEpidermal growth factor receptor2.7.10.10.445
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.445
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.445
4zohFADPutative oxidoreductase FAD-binding subunit/0.445
5f54TMPSingle-stranded-DNA-specific exonuclease/0.445
1g5sI17Cyclin-dependent kinase 22.7.11.220.444
1pkdUCNCyclin-dependent kinase 22.7.11.220.444
1y91CT9Cyclin-dependent kinase 22.7.11.220.444
2vx17X8Ephrin type-B receptor 42.7.10.10.444
2xyuQ9GEphrin type-A receptor 42.7.10.10.444
2yn8STUEphrin type-B receptor 42.7.10.10.444
3bu5ATPInsulin receptor2.7.10.10.444
3c50ADPRhodopsin kinase/0.444
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
4a6nFADTetX family tetracycline inactivation enzyme/0.444
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.444
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
4gmy0X5Tyrosine-protein kinase JAK2/0.444
4iva1J5Tyrosine-protein kinase JAK2/0.444
4jbpYPHAurora kinase A2.7.11.10.444
4oauADP2-5A-dependent ribonuclease3.1.260.444
4u03GTPCyclic GMP-AMP synthase/0.444
5av3KMPDeath-associated protein kinase 12.7.11.10.444
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.444
1h1s4SPCyclin-dependent kinase 22.7.11.220.443
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.443
2vv9IM9Cyclin-dependent kinase 22.7.11.220.443
3hllI45Mitogen-activated protein kinase 14/0.443
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.443
3qtuX44Cyclin-dependent kinase 22.7.11.220.443
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.443
3v9y24LPeroxisome proliferator-activated receptor gamma/0.443
4aotGW8Serine/threonine-protein kinase 102.7.11.10.443
4bbe3O4Tyrosine-protein kinase JAK2/0.443
4dgnLU2Casein kinase II subunit alpha2.7.11.10.443
4e4m0NHTyrosine-protein kinase JAK2/0.443
4en4ATPPyridoxal kinase2.7.1.350.443
4f9fGDPPutative glycosyltransferase/0.443
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.443
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.443
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1jkkANPDeath-associated protein kinase 12.7.11.10.442
1m2rMNYCasein kinase II subunit alpha2.7.11.10.442
1mq4ADPAurora kinase A2.7.11.10.442
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.442
2v7a627Tyrosine-protein kinase ABL12.7.10.20.442
2vwy7X5Ephrin type-B receptor 42.7.10.10.442
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3eyhIZATyrosine-protein kinase JAK1/0.442
3qx2X63Cyclin-dependent kinase 22.7.11.220.442
3rni21ZCyclin-dependent kinase 22.7.11.220.442
3sw719KCyclin-dependent kinase 22.7.11.220.442
3zxtACPDeath-associated protein kinase 12.7.11.10.442
4eor4SPCyclin-dependent kinase 22.7.11.220.442
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.442
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.442
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.442
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.442
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4iwd1JCHepatocyte growth factor receptor2.7.10.10.442
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.442
4o0wADNAurora kinase A2.7.11.10.442
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.442
4xlvACPInsulin receptor2.7.10.10.442
4yuqKS1Calmodulin-like domain protein kinase/0.442
5auwQUEDeath-associated protein kinase 12.7.11.10.442
1gii1PUCyclin-dependent kinase 22.7.11.220.441
1h0w207Cyclin-dependent kinase 22.7.11.220.441
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.441
2vwz7X6Ephrin type-B receptor 42.7.10.10.441
2xuuADPDeath-associated protein kinase 12.7.11.10.441
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3cukFADD-amino-acid oxidase1.4.3.30.441
3d8bADPFidgetin-like protein 13.6.40.441
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3rk507ZCyclin-dependent kinase 22.7.11.220.441
4bgh3I6Cyclin-dependent kinase 22.7.11.220.441
4btmF8ETau-tubulin kinase 12.7.11.10.441
4fkr45KCyclin-dependent kinase 22.7.11.220.441
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4mwhATPCasein kinase II subunit alpha2.7.11.10.441
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.441
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.441
1a72PADAlcohol dehydrogenase E chain1.1.1.10.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2dcnADP2-keto-3-deoxy-gluconate kinase/0.440
2dwbANPAurora kinase A2.7.11.10.440
2izsBRQCasein kinase I isoform gamma-32.7.11.10.440
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2w4kADPDeath-associated protein kinase 12.7.11.10.440
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
3c4wATPRhodopsin kinase/0.440
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.440
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.440
3mqe416Prostaglandin G/H synthase 21.14.99.10.440
3q43D66M1 family aminopeptidase3.4.110.440
3r7yZ04Cyclin-dependent kinase 22.7.11.220.440
3vn9ANKDual specificity mitogen-activated protein kinase kinase 62.7.12.20.440
4c59FEFCyclin-G-associated kinase2.7.11.10.440
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4fi1ATPCasein kinase II subunit alpha2.7.11.10.440
4oavACP2-5A-dependent ribonuclease3.1.260.440
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.440