scPDB - Distribution of Binding site Similarity values of 5e6y entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5e6y	ACX	1,4-alpha-glucan branching enzyme GlgB

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5e6y	ACX	1,4-alpha-glucan branching enzyme GlgB	/	1.000
1lf2	R37	Plasmepsin-2	3.4.23.39	0.487
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.477
2v16	C47	Renin	3.4.23.15	0.475
3ufl	508	Beta-secretase 1	3.4.23.46	0.472
1w6h	TIT	Plasmepsin-2	3.4.23.39	0.471
1rsz	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.470
2mm3	CHO	Gastrotropin	/	0.469
4b77	54M	Beta-secretase 1	3.4.23.46	0.469
3pbz	F02	Endothiapepsin	3.4.23.22	0.466
1qti	GNT	Acetylcholinesterase	3.1.1.7	0.465
3bm1	FMN	Putative NAD(P)H nitroreductase YdjA	/	0.465
3ojx	FMN	NADPH--cytochrome P450 reductase	/	0.465
4u9z	COA	Alpha-tubulin N-acetyltransferase 1	/	0.465
2zru	FMN	Isopentenyl-diphosphate delta-isomerase	/	0.464
4fri	DWA	Beta-secretase 1	3.4.23.46	0.464
2ph6	712	Beta-secretase 1	3.4.23.46	0.463
4c02	TAK	Activin receptor type-1	2.7.11.30	0.463
4gv4	MEJ	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.463
4h12	SAH	Histone-lysine N-methyltransferase SETD2	2.1.1.43	0.463
3hy7	097	A disintegrin and metalloproteinase with thrombospondin motifs 5	3.4.24	0.462
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.462
3q5p	TAC	Multidrug-efflux transporter 1 regulator	/	0.461
3cid	318	Beta-secretase 1	3.4.23.46	0.460
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.460
2whq	HI6	Acetylcholinesterase	3.1.1.7	0.459
4h3j	10W	Beta-secretase 1	3.4.23.46	0.459
1z5u	CMP	Class B acid phosphatase	/	0.458
2qjp	ANJ	Cytochrome b	/	0.457
3w5u	FAD	Ferredoxin	/	0.457
3zec	ANP	Adenosine monophosphate-protein transferase SoFic	2.7.7.n1	0.457
4b14	4XB	Glycylpeptide N-tetradecanoyltransferase	/	0.457
4b78	KGG	Beta-secretase 1	3.4.23.46	0.457
4k39	SAM	Anaerobic sulfatase-maturating enzyme	1.8.98	0.457
1p0p	BCH	Cholinesterase	3.1.1.8	0.456
2fdp	FRP	Beta-secretase 1	3.4.23.46	0.456
3jpu	TY4	Transcriptional activator protein LasR	/	0.456
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.456
4dh6	0KN	Beta-secretase 1	3.4.23.46	0.455
4jq1	NPS	Aldo-keto reductase family 1 member C2	/	0.455
3nya	JTZ	Beta-2 adrenergic receptor	/	0.455
2zrz	FNR	Isopentenyl-diphosphate delta-isomerase	/	0.454
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.453
3dys	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.453
3vyd	VYD	Renin	3.4.23.15	0.453
4h3f	10O	Beta-secretase 1	3.4.23.46	0.453
1dg5	TOP	Dihydrofolate reductase	1.5.1.3	0.452
3hy9	098	A disintegrin and metalloproteinase with thrombospondin motifs 5	3.4.24	0.452
3ix4	TX1	Transcriptional activator protein LasR	/	0.452
3k5d	XLI	Beta-secretase 1	3.4.23.46	0.452
4da7	AC2	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.452
2xnv	VU3	Soluble acetylcholine receptor	/	0.451
4y38	0A9	Endothiapepsin	3.4.23.22	0.451
1qrp	HH0	Pepsin A-4	3.4.23.1	0.450
4b05	32D	Beta-secretase 1	3.4.23.46	0.450
1ihi	IU5	Aldo-keto reductase family 1 member C2	/	0.449
1k7f	IAV	Tryptophan synthase alpha chain	/	0.449
1lb9	DNQ	Glutamate receptor 2	/	0.449
1xqp	8HG	N-glycosylase/DNA lyase	/	0.449
3fpk	FAD	Ferredoxin-NADP reductase	/	0.449
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.449
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
4gv0	8ME	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.449
1bil	0IU	Renin	3.4.23.15	0.448
1jdz	FMB	Purine nucleoside phosphorylase	/	0.448
1kzi	THG	Thymidylate synthase	/	0.448
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.448
1p91	SAM	23S rRNA (guanine(745)-N(1))-methyltransferase	/	0.448
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.448
1w29	TS0	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.448
2a4x	BLM	Mitomycin-binding protein	/	0.448
2isc	223	Purine nucleoside phosphorylase, putative	/	0.448
3dyl	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.448
3udq	09E	Beta-secretase 1	3.4.23.46	0.448
4djx	0KQ	Beta-secretase 1	3.4.23.46	0.448
4gv8	DUP	DUTPase	/	0.448
1bx9	GLY_GGL_FOE	Glutathione S-transferase F2	2.5.1.18	0.447
1xf0	ASD	Aldo-keto reductase family 1 member C3	/	0.447
2zwa	SAH	tRNA wybutosine-synthesizing protein 4	2.1.1.290	0.447
3fr2	8CA	Fatty acid-binding protein, adipocyte	/	0.447
5hyn	SAH	Histone-lysine N-methyltransferase EZH2	2.1.1.43	0.447
1rt9	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.446
2oaz	I96	Methionine aminopeptidase 2	/	0.446
2r6h	FAD	Na(+)-translocating NADH-quinone reductase subunit F	/	0.446
3pm1	ET	HTH-type transcriptional regulator QacR	/	0.446
3qi4	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
3u9f	CLM	Chloramphenicol acetyltransferase	2.3.1.28	0.446
4b66	NAP	L-ornithine N(5)-monooxygenase	/	0.446
4y35	F90	Endothiapepsin	3.4.23.22	0.446
1ib0	FAD	NADH-cytochrome b5 reductase 3	1.6.2.2	0.445
1lf3	EH5	Plasmepsin-2	3.4.23.39	0.445
1od1	0QS	Endothiapepsin	3.4.23.22	0.445
1t4c	COA	Formyl-CoA:oxalate CoA-transferase	/	0.445
4g09	0VD	Histidinol dehydrogenase	/	0.445
4hbm	0Y7	E3 ubiquitin-protein ligase Mdm2	6.3.2	0.445
4zir	ANP	Energy-coupling factor transporter ATP-binding protein EcfA2	3.6.3	0.445
4zir	ANP	Energy-coupling factor transporter ATP-binding protein EcfA1	/	0.445
2xkd	T3M	Serine/threonine-protein kinase Nek2	2.7.11.1	0.444
3oqf	S51	Renin	3.4.23.15	0.444
4a6a	TTP	dCTP deaminase	3.5.4.13	0.444
4dvq	1CA	Cytochrome P450 11B2, mitochondrial	1.14.15.4	0.444
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.444
4o7n	ADP	Phosphoribosylaminoimidazole-succinocarboxamide synthase	6.3.2.6	0.444
1h69	ARH	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
1rsg	FAD	Polyamine oxidase FMS1	/	0.443
2a0x	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.443
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
5egh	PC	Ectonucleotide pyrophosphatase/phosphodiesterase family member 6	/	0.443
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.442
1m9m	6NI	Nitric oxide synthase, endothelial	1.14.13.39	0.442
2ywv	ADP	Phosphoribosylaminoimidazole-succinocarboxamide synthase	/	0.442
3jyq	NAD	Quinate/shikimate dehydrogenase (NAD(+))	/	0.442
3zc3	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.442
5buk	FAD	FADH2-dependent halogenase	/	0.442
3br3	ET	HTH-type transcriptional regulator QacR	/	0.441
3djj	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.441
3jsi	WTC	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
3pld	F90	Endothiapepsin	3.4.23.22	0.441
4a86	H35	Major pollen allergen Bet v 1-A	/	0.441
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.441
4dmg	SAM	Uncharacterized protein	/	0.441
5c6c	CMP	cGMP-dependent protein kinase 2	2.7.11.12	0.441
1kwc	BPY	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.440
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.440
2a0y	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.440
3bjc	WAN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.440
3prs	RIT	Endothiapepsin	3.4.23.22	0.440
3rtn	RTN	Beta-secretase 1	3.4.23.46	0.440
4h3g	10Q	Beta-secretase 1	3.4.23.46	0.440
4qa0	SHH	Histone deacetylase 8	3.5.1.98	0.440
4rrw	LUR	Prostaglandin G/H synthase 2	1.14.99.1	0.440
4rrz	LUR	Prostaglandin G/H synthase 2	1.14.99.1	0.440
4xvy	SAH	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.440