scPDB - Distribution of Binding site Similarity values of 5dto entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
5dto	SAH	Genome polyprotein

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5dto	SAH	Genome polyprotein	/	1.000
5jjs	SAH	Genome polyprotein	/	0.609
2pxa	SAH	Genome polyprotein	2.7.7.48	0.601
3p97	SAM	Genome polyprotein	2.1.1.56	0.590
3p8z	36A	Genome polyprotein	2.1.1.56	0.588
4ctj	SAM	Genome polyprotein	/	0.584
2p3q	SAH	Genome polyprotein	/	0.572
3eld	SFG	Methyltransferase	/	0.568
3evb	SAH	Genome polyprotein	2.1.1.56	0.568
1l9k	SAH	Genome polyprotein	2.7.7.48	0.564
5cuq	NSC	Genome polyprotein	/	0.562
5jjr	SAH	Genome polyprotein	/	0.559
2p41	SAH	Genome polyprotein	/	0.554
2p1d	SAH	Genome polyprotein	2.7.7.48	0.551
3p8z	SAH	Genome polyprotein	2.1.1.56	0.548
2px5	SAH	Genome polyprotein	2.7.7.48	0.536
3ely	SAH	Methyltransferase	/	0.531
3eva	SAH	Genome polyprotein	2.1.1.56	0.522
3evc	SAH	Genome polyprotein	2.1.1.56	0.520
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.514
2xbm	SAH	Genome polyprotein	/	0.511
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.509
2ivi	ACW	Isopenicillin N synthase	1.21.3.1	0.507
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.506
3gnc	QQQ	Glutaryl-CoA dehydrogenase	/	0.505
3zoi	M2W	Isopenicillin N synthase	1.21.3.1	0.503
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.503
2px2	SAH	Genome polyprotein	2.7.7.48	0.501
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.501
1dli	UDX	UDP-glucose 6-dehydrogenase	/	0.498
3fhx	PLP	Pyridoxal kinase	2.7.1.35	0.498
1l8q	ADP	Chromosomal replication initiator protein DnaA	/	0.496
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.496
2vbd	V10	Isopenicillin N synthase	1.21.3.1	0.495
2wa2	SAM	Genome polyprotein	/	0.493
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.492
3tm5	SFG	Uncharacterized protein	/	0.492
4a83	DXC	Major pollen allergen Bet v 1-A	/	0.490
2wo7	ASV	Isopenicillin N synthase	1.21.3.1	0.489
5c6c	CMP	cGMP-dependent protein kinase 2	2.7.11.12	0.488
1w06	W05	Isopenicillin N synthase	1.21.3.1	0.487
4gyz	D5M	Tyrosyl-DNA phosphodiesterase 2	3.1.4	0.487
2toh	HBI	Tyrosine 3-monooxygenase	1.14.16.2	0.486
2x19	GTP	GTP-binding nuclear protein GSP1/CNR1	/	0.486
3r6s	CMP	CRP-like cAMP-activated global transcriptional regulator	/	0.486
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.484
1dlj	UGA	UDP-glucose 6-dehydrogenase	/	0.484
4fhd	0TT	Spore photoproduct lyase	/	0.483
1rh3	MTX	Dihydrofolate reductase	1.5.1.3	0.482
4a81	DXC	Major pollen allergen Bet v 1-A	/	0.482
1rft	PXM	Pyridoxal kinase	2.7.1.35	0.481
2jb4	A14	Isopenicillin N synthase	1.21.3.1	0.481
2zi5	3L1	Deoxycytidine kinase	2.7.1.74	0.481
4y9x	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.481
1r6a	SAH	Genome polyprotein	2.7.7.48	0.480
3ule	C69	Actin-related protein 3	/	0.480
4fhb	FOL	Dihydrofolate reductase	1.5.1.3	0.480
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.479
1hb1	OCV	Isopenicillin N synthase	1.21.3.1	0.478
1gky	5GP	Guanylate kinase	2.7.4.8	0.477
4iji	99T	Glutathione S-transferase-like protein YibF	/	0.477
4nmc	FAD	Bifunctional protein PutA	/	0.477
1ygj	RMC	Pyridoxal kinase	2.7.1.35	0.475
2pl0	STI	Tyrosine-protein kinase Lck	2.7.10.2	0.475
2w9h	TOP	Dihydrofolate reductase	1.5.1.3	0.475
4bfw	ZVW	Pantothenate kinase	2.7.1.33	0.475
1tow	CRZ	Fatty acid-binding protein, adipocyte	/	0.474
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.474
3qpo	PFR	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.474
4la7	A1O	Abscisic acid receptor PYL2	/	0.474
3exh	TPP	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	1.2.4.1	0.473
3exh	TPP	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	1.2.4.1	0.473
3nga	3NG	Casein kinase II subunit alpha	2.7.11.1	0.473
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.473
1cqp	803	Integrin alpha-L	/	0.472
2nnq	T4B	Fatty acid-binding protein, adipocyte	/	0.472
1if7	SBR	Carbonic anhydrase 2	4.2.1.1	0.471
1xzq	FON	tRNA modification GTPase MnmE	3.6.5	0.471
3c3e	FO1	2-phospho-L-lactate transferase	/	0.471
3x04	GNP	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	2.7.1.149	0.471
1uzw	CDH	Isopenicillin N synthase	1.21.3.1	0.470
3c35	KAI	Glutamate receptor ionotropic, kainate 1	/	0.470
3keq	NAD	Redox-sensing transcriptional repressor Rex	/	0.470
3ql3	FOL	Dihydrofolate reductase	1.5.1.3	0.470
1hb3	SCV	Isopenicillin N synthase	1.21.3.1	0.469
1iol	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.469
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.469
2zyn	BCD	Periplasmic binding protein	/	0.469
3ahi	HTL	Probable phosphoketolase	/	0.469
3bkb	STU	Tyrosine-protein kinase Fes/Fps	2.7.10.2	0.469
2hb7	O1C	Vitamin D3 receptor	/	0.468
4eqx	FAD	Coenzyme A disulfide reductase	/	0.468
4y6u	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.468
1ao8	MTX	Dihydrofolate reductase	1.5.1.3	0.467
1f5f	DHT	Sex hormone-binding globulin	/	0.467
2ydx	STL	Methionine adenosyltransferase 2 subunit beta	/	0.467
3f63	GTX	Glutathione transferase GST1-4	/	0.467
4ap1	NAP	Steroid monooxygenase	/	0.467
1dre	MTX	Dihydrofolate reductase	1.5.1.3	0.466
1n5v	NOM	ActVA 6 protein	/	0.466
2zjw	REF	Casein kinase II subunit alpha	2.7.11.1	0.466
3pqb	VGP	Putative oxidoreductase	/	0.466
4hy6	FJ1	Heat shock protein HSP 90-alpha	/	0.466
7std	CRP	Scytalone dehydratase	4.2.1.94	0.466
1dpm	EBP	Parathion hydrolase	3.1.8.1	0.465
4bfz	ZVZ	Pantothenate kinase	2.7.1.33	0.465
4bkj	STI	Epithelial discoidin domain-containing receptor 1	2.7.10.1	0.465
4dp3	MMV	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.465
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.465
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.465
4ho9	GDU	Glucose-1-phosphate thymidylyltransferase	/	0.465
1f8g	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.464
1fdu	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.464
1u1j	C2F	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1	2.1.1.14	0.464
2chx	090	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.464
2v5a	LZL	Biotin carboxylase	6.3.4.14	0.464
4s1i	PLP	Pyridoxal kinase, putative	/	0.464
1rx1	NAP	Dihydrofolate reductase	1.5.1.3	0.463
2bik	BI1	Serine/threonine-protein kinase pim-1	2.7.11.1	0.463
3t5i	SER_SER_CMT_FAR	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.463
4d9f	DCS	D-cysteine desulfhydrase	/	0.463
1qpj	STU	Tyrosine-protein kinase Lck	2.7.10.2	0.462
1ra2	FOL	Dihydrofolate reductase	1.5.1.3	0.462
2bl4	NAD	Lactaldehyde reductase	1.1.1.77	0.462
2vo4	GTB	2,4-D inducible glutathione S-transferase	/	0.462
3arv	SAU	Chitinase A	/	0.462
3b4y	F42	F420-dependent glucose-6-phosphate dehydrogenase	/	0.462
3l1c	ADP	Protein claret segregational	/	0.462
3qlr	NDP	Dihydrofolate reductase	1.5.1.3	0.462
4cf7	ADP	Adenylate kinase	/	0.462
4l0q	NAD	Alcohol dehydrogenase class-3	/	0.462
5c7o	NAD	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	1.2.1.12	0.462
1h2b	NAJ	NAD-dependent alcohol dehydrogenase	/	0.461
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.461
3pm9	FAD	Putative oxidoreductase	/	0.461
3uov	FAD	2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase	1.14.13.160	0.461
4dpu	AGS	Mevalonate diphosphate decarboxylase	/	0.461
4y6n	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.461
1gzu	NMN	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1	2.7.7.1	0.460
1rd4	L08	Integrin alpha-L	/	0.460
2cje	DUN	DUTPase	/	0.460
2y60	M8F	Isopenicillin N synthase	1.21.3.1	0.460
2yx6	ADP	Uncharacterized protein	/	0.460
3qgt	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.460
3s1d	ZIR	Cytokinin dehydrogenase 1	1.5.99.12	0.460
4c9o	CAM	Cytochrome P450	/	0.460
4imf	SI3	N-acetylneuraminate lyase	/	0.460
4x81	MVI	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.460
1aoe	GW3	Dihydrofolate reductase	1.5.1.3	0.459
1gpe	FAD	Glucose oxidase	1.1.3.4	0.459
1rkh	VD2	Vitamin D3 receptor	/	0.459
1ykd	CMP	Adenylate cyclase	/	0.459
3cse	N22	Uncharacterized protein	/	0.459
3eps	ATP	Isocitrate dehydrogenase kinase/phosphatase	/	0.459
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.459
1vbi	NAD	Malate/L-lactate dehydrogenase family protein	/	0.458
1zky	689	Estrogen receptor	/	0.458
2i0v	6C3	Macrophage colony-stimulating factor 1 receptor	2.7.10.1	0.458
3dcs	MZM	Carbonic anhydrase 2	4.2.1.1	0.458
4a84	DXC	Major pollen allergen Bet v 1-A	/	0.458
4l1x	STR	Aldo-keto reductase family 1 member C2	/	0.458
4ly9	1YY	Glucokinase regulatory protein	/	0.458
4okk	U5P	3'-5' exoribonuclease MT2234.1	/	0.458
4x7w	MVI	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.458
5dhg	DGV	Nociceptin receptor	/	0.458
1klk	PMD	Dihydrofolate reductase	1.5.1.3	0.457
1tdu	DUR	Thymidylate synthase	/	0.457
2a8s	GTP	U8 snoRNA-decapping enzyme	/	0.457
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.457
2g97	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.457
2hb8	MVD	Vitamin D3 receptor	/	0.457
2rh9	IGP	Tryptophan synthase alpha chain	/	0.457
3qge	26F	Genome polyprotein	2.7.7.48	0.457
3v1s	0LH	Strictosidine synthase	4.3.3.2	0.457
3zku	HCV	Isopenicillin N synthase	1.21.3.1	0.457
4fr4	STU	Serine/threonine-protein kinase 32A	2.7.11.1	0.457
4u7w	NDP	MxaA	/	0.457
1gc5	ADP	ADP-dependent glucokinase	2.7.1.147	0.456
1jpa	ANP	Ephrin type-B receptor 2	2.7.10.1	0.456
1l3i	SAH	Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)	/	0.456
1nen	DNT	Succinate dehydrogenase iron-sulfur subunit	1.3.5.1	0.456
1nen	DNT	Succinate dehydrogenase cytochrome b556 subunit	/	0.456
1s1w	UC1	Gag-Pol polyprotein	2.7.7.49	0.456
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.456
2c31	TZD	Oxalyl-CoA decarboxylase	4.1.1.8	0.456
3oim	VZ5	Carbonic anhydrase 2	4.2.1.1	0.456
4kf1	HT5	Aryldialkylphosphatase	3.1.8.1	0.456
4lga	A2O	Abscisic acid receptor PYL2	/	0.456
5c1m	CLR	Mu-type opioid receptor	/	0.456
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.455
1p33	MTX	Pteridine reductase 1	1.5.1.33	0.455
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.455
1tou	B1V	Fatty acid-binding protein, adipocyte	/	0.455
1zrz	BI1	Protein kinase C iota type	2.7.11.13	0.455
2b53	D23	Cyclin-dependent kinase 2	2.7.11.22	0.455
2zym	ACX	Periplasmic binding protein	/	0.455
3cd5	7HI	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.455
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.455
3fuf	BES	Leukotriene A-4 hydrolase	3.3.2.6	0.455
3i58	7NA	2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase	/	0.455
3tda	PN0	Cytochrome P450 2D6	/	0.455
4fxf	ATP	Pyruvate kinase PKM	2.7.1.40	0.455
4v0s	2HN	3-dehydroquinate dehydratase	4.2.1.10	0.455
4xbf	FAD	Lysine-specific histone demethylase 1A	1	0.455
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.454
1opb	RET	Retinol-binding protein 2	/	0.454
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.454
1xe6	5FP	Plasmepsin-2	3.4.23.39	0.454
2gjl	FMN	Nitronate monooxygenase	1.13.12.16	0.454
3qvr	FAD	Glucose oxidase	1.1.3.4	0.454
3to3	ATP	Petrobactin biosynthesis protein AsbB	/	0.454
3tw6	ADP	Pyruvate carboxylase	/	0.454
4anu	EM7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.454
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.454
4feu	537	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.454
4fhf	0TT	Spore photoproduct lyase	/	0.454
4fvq	ATP	Tyrosine-protein kinase JAK2	/	0.454
4n57	ADP	APH(2'')-Id	/	0.454
4x7z	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.454
1bdl	IM1	Gag-Pol polyprotein	3.4.23.16	0.453
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.453
1pqc	444	Oxysterols receptor LXR-beta	/	0.453
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.453
2g8y	NAD	Hydroxycarboxylate dehydrogenase B	/	0.453
2pnc	CLU	Primary amine oxidase, liver isozyme	/	0.453
3dge	ADP	Sensor histidine kinase	/	0.453
3fr4	F8A	Fatty acid-binding protein, adipocyte	/	0.453
3nmn	PYV	Abscisic acid receptor PYL1	/	0.453
4f3g	KAI	Glutamate receptor 3	/	0.453
4g2l	0WL	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.453
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.453
4mv3	ACP	Biotin carboxylase	6.3.4.14	0.453
5hwr	COA	Hydroxymethylglutaryl-CoA synthase	/	0.453
3nya	JTZ	Beta-2 adrenergic receptor	/	0.453
1kbj	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.452
1mxf	MTX	Putative pteridine reductase 2	/	0.452
1omo	NAD	Alanine dehydrogenase	/	0.452
1qv1	CZH	Obelin	/	0.452
1zdw	FLV	Prenyltransferase	/	0.452
2uxi	G50	HTH-type transcriptional regulator TtgR	/	0.452
2vax	CSC	Acetyl-CoA--deacetylcephalosporin C acetyltransferase	2.3.1.175	0.452
3af1	GDP	Pantothenate kinase	2.7.1.33	0.452
3fr5	I4A	Fatty acid-binding protein, adipocyte	/	0.452
3kb0	A8S	Abscisic acid receptor PYL2	/	0.452
3ldo	ANP	78 kDa glucose-regulated protein	/	0.452
3nuv	ASD	Steroid Delta-isomerase	5.3.3.1	0.452
3pn1	IVH	DNA ligase	/	0.452
3tfy	COA	N-alpha-acetyltransferase 50	2.3.1	0.452
3tk3	CPZ	Cytochrome P450 2B4	1.14.14.1	0.452
3v2b	AR6	Poly [ADP-ribose] polymerase 15	2.4.2.30	0.452
4oh4	ANP	Protein BRASSINOSTEROID INSENSITIVE 1	2.7.10.1	0.452
4ol0	GTP	GTP-binding nuclear protein Ran	/	0.452
4x7u	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.452
5dhh	DGW	Nociceptin receptor	/	0.452
1bn1	AL5	Carbonic anhydrase 2	4.2.1.1	0.451
1d2s	DHT	Sex hormone-binding globulin	/	0.451
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.451
1lb9	DNQ	Glutamate receptor 2	/	0.451
1rl3	PCG	cAMP-dependent protein kinase type I-alpha regulatory subunit	/	0.451
1tkc	M6T	Transketolase 1	2.2.1.1	0.451
1uze	EAL	Angiotensin-converting enzyme	3.2.1	0.451
1ygk	RRC	Pyridoxal kinase	2.7.1.35	0.451
2a9y	26A	Adenosine kinase	2.7.1.20	0.451
2fsz	OHT	Estrogen receptor beta	/	0.451
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.451
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.451
2zi6	3D1	Deoxycytidine kinase	2.7.1.74	0.451
3ed1	GA3	Gibberellin receptor GID1	/	0.451
3qiz	QI2	Botulinum neurotoxin type A	3.4.24.69	0.451
3w9r	A8S	Abscisic acid receptor PYL9	/	0.451
4dc0	NDP	Putative ketoacyl reductase	1.3.1	0.451
4o4f	ATP	Kinase	/	0.451
7dfr	FOL	Dihydrofolate reductase	1.5.1.3	0.451
1dr3	TAP	Dihydrofolate reductase	1.5.1.3	0.450
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.450
1t88	CAM	Camphor 5-monooxygenase	1.14.15.1	0.450
2oxt	SAM	Genome polyprotein	/	0.450
2rl1	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.450
2w6p	OA4	Biotin carboxylase	6.3.4.14	0.450
2x06	NAD	L-sulfolactate dehydrogenase	/	0.450
2xvv	9DN	Serum albumin	/	0.450
3c3x	NAP	Eugenol synthase 1	1.1.1.318	0.450
3gwf	NAP	Cyclohexanone monooxygenase	/	0.450
3mdm	FJZ	Cholesterol 24-hydroxylase	/	0.450
3qfx	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.450
3swq	EPU	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.450
3tvq	DQH	Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN	2.1.1	0.450
3w3l	RX8	Toll-like receptor 8	/	0.450
4awm	KDH	Polymerase acidic protein	/	0.450
4ehy	ADP	Tetraacyldisaccharide 4'-kinase	/	0.450
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.450
4u0s	ADP	Adenosine monophosphate-protein transferase FICD	2.7.7.n1	0.450
1cs4	FOK	Adenylate cyclase type 2	/	0.449
1cs4	FOK	Adenylate cyclase type 5	/	0.449
1q20	PLO	Sulfotransferase family cytosolic 2B member 1	2.8.2.2	0.449
1szm	BI4	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.449
1y56	FMN	Uncharacterized protein	/	0.449
1y56	FMN	382aa long hypothetical sarcosine oxidase	/	0.449
2d1y	NAD	Oxidoreductase, short-chain dehydrogenase/reductase family	/	0.449
2xtn	GTP	GTPase IMAP family member 2	/	0.449
3d9z	D9Z	Carbonic anhydrase 2	4.2.1.1	0.449
3eem	53V	Uncharacterized protein	/	0.449
3ha5	SFG	Hydroxymycolate synthase MmaA4	2.1.1	0.449
3i1y	33N	Bifunctional epoxide hydrolase 2	3.3.2.10	0.449
3lqf	NAD	Galactitol dehydrogenase	/	0.449
3m6p	BB2	Peptide deformylase 1B, chloroplastic/mitochondrial	3.5.1.88	0.449
3qen	5BT	Deoxycytidine kinase	2.7.1.74	0.449
3um6	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.449
4e37	NDP	Catalase	1.11.1.6	0.449
4wa9	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.449
4x5g	FOL	Dihydrofolate reductase	1.5.1.3	0.449
5std	UNN	Scytalone dehydratase	4.2.1.94	0.449
4s0v	SUV	Orexin receptor type 2	/	0.449
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.448
1eji	THF	Serine hydroxymethyltransferase, cytosolic	/	0.448
1hnv	TBO	Gag-Pol polyprotein	2.7.7.49	0.448
1u0h	FOK	Adenylate cyclase type 2	/	0.448
1u0h	FOK	Adenylate cyclase type 5	/	0.448
1u71	MXA	Dihydrofolate reductase	1.5.1.3	0.448
1x14	NAD	NAD(P) transhydrogenase subunit alpha	1.6.1.2	0.448
2bu9	HFV	Isopenicillin N synthase	1.21.3.1	0.448
2oc4	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.448
2par	TMP	5'-deoxynucleotidase YfbR	/	0.448
2weh	FB1	Carbonic anhydrase 2	4.2.1.1	0.448
3fr2	8CA	Fatty acid-binding protein, adipocyte	/	0.448
3s8a	DGT	Ribonucleoside-diphosphate reductase large chain 1	1.17.4.1	0.448
4h4d	10E	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	/	0.448
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.448
4lb2	DM5	Serum albumin	/	0.448
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.448
4wh3	ATP	N-acetylhexosamine 1-kinase	2.7.1.162	0.448
4wuo	NAD	3-isopropylmalate dehydrogenase	1.1.1.85	0.448
3g5q	FAD	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	/	0.447
3lfm	3DT	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.447
3n3z	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.447
3qiy	QI1	Botulinum neurotoxin type A	3.4.24.69	0.447
3te4	ACO	Dopamine N-acetyltransferase	/	0.447
3uvq	FS8	Mitogen-activated protein kinase 14	/	0.447
3w5r	LOA	Vitamin D3 receptor	/	0.447
3wyg	GTP	GTP-binding nuclear protein GSP1/CNR1	/	0.447
4aw0	ATP	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.447
4bis	8HQ	Lysine-specific demethylase 4A	1.14.11	0.447
4ej7	ATP	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.447
4g1z	0VP	Vitamin D3 receptor A	/	0.447
4g8z	TOP	Dihydrofolate reductase	1.5.1.3	0.447
4glx	0XS	DNA ligase	6.5.1.2	0.447
4ixd	1HV	Integrin alpha-L	/	0.447
4pao	GSP	Guanine nucleotide-binding protein G(i) subunit alpha-1	/	0.447
4prx	ADP	DNA gyrase subunit B	/	0.447
4r7u	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.447
5a88	ADP	Riboflavin biosynthesis protein RibF	2.7.1.26	0.447
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.446
1kfb	IGP	Tryptophan synthase alpha chain	/	0.446
1m8g	NAD	Nicotinamide-nucleotide adenylyltransferase	2.7.7.1	0.446
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.446
1syn	F89	Thymidylate synthase	/	0.446
1uvr	BI8	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.446
2izk	GLL	Streptavidin	/	0.446
2wi7	2KL	Heat shock protein HSP 90-alpha	/	0.446
3c14	FOK	Adenylate cyclase type 2	/	0.446
3c14	FOK	Adenylate cyclase type 5	/	0.446
3hu1	AGS	Transitional endoplasmic reticulum ATPase	3.6.4.6	0.446
3jun	AKD	Phenazine biosynthesis protein A/B	/	0.446
3lkz	SFG	Genome polyprotein	/	0.446
3maa	FKP	Adenylate cyclase type 2	/	0.446
3maa	FKP	Adenylate cyclase type 5	/	0.446
3p2e	SAH	16S rRNA (adenine(1408)-N(1))-methyltransferase	2.1.1.180	0.446
3ppk	FNI	Serine/threonine-protein kinase B-raf	2.7.11.1	0.446
3zei	AWH	O-acetylserine sulfhydrylase	/	0.446
4iae	1DX	Alr2278 protein	/	0.446
4jem	C5P	CMP/hydroxymethyl CMP hydrolase	/	0.446
1eio	GCH	Gastrotropin	/	0.445
1fw0	KAI	Glutamate receptor 2	/	0.445
1h5r	THM	Glucose-1-phosphate thymidylyltransferase 1	/	0.445
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.445
1m78	CLZ	Dihydrofolate reductase	1.5.1.3	0.445
1odn	APV	Isopenicillin N synthase	1.21.3.1	0.445
1rdw	LAR	Actin, alpha skeletal muscle	/	0.445
1x1a	SAM	C-20 methyltransferase	/	0.445
1xel	UPG	UDP-glucose 4-epimerase	5.1.3.2	0.445
2xau	ADP	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43	3.6.4.13	0.445
2y6f	M9F	Isopenicillin N synthase	1.21.3.1	0.445
3b9l	AZZ	Serum albumin	/	0.445
3dxm	N24	Actin-related protein 3	/	0.445
3dy8	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.445
3ey4	352	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.445
3iog	SDF	Metallo-beta-lactamase type 2	/	0.445
3l03	4OH	Estrogen receptor	/	0.445
3n0z	3AT	Adenylate cyclase 2	/	0.445
3p67	FMN	Pentaerythritol tetranitrate reductase	/	0.445
3qly	55V	Uncharacterized protein	/	0.445
4dh6	0KN	Beta-secretase 1	3.4.23.46	0.445
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.445
4i8v	BHF	Cytochrome P450 1A1	1.14.14.1	0.445
4kap	1QV	Carbonic anhydrase 2	4.2.1.1	0.445
4kwi	1TJ	Reductase homolog	/	0.445
5dqr	FAD	7-hydroxymethyl chlorophyll a reductase, chloroplastic	1.17.7.2	0.445
5eja	TD6	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	/	0.445
5j60	FAD	Thioredoxin reductase	/	0.445
3d4s	TIM	Beta-2 adrenergic receptor	/	0.445
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.444
1mrq	STR	Aldo-keto reductase family 1 member C1	/	0.444
1q43	CMP	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	/	0.444
1uae	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.444
1w76	GNT	Acetylcholinesterase	3.1.1.7	0.444
1zkl	IBM	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	3.1.4.53	0.444
2f7x	4EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.444
2h2q	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.444
2qbl	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
3br3	ET	HTH-type transcriptional regulator QacR	/	0.444
3fkn	FKN	Mitogen-activated protein kinase 14	/	0.444
3fzf	ATP	Heat shock cognate 71 kDa protein	/	0.444
3ggc	H26	Hypoxanthine-guanine phosphoribosyltransferase	2.4.2.8	0.444
3gue	UPG	UTP-glucose-1-phosphate uridylyltransferase 2, putative	/	0.444
3lfc	Z86	Mitogen-activated protein kinase 14	/	0.444
3q9b	B3N	Acetylpolyamine amidohydrolase	/	0.444
3qlr	QLR	Dihydrofolate reductase	1.5.1.3	0.444
3t3r	9PL	Cytochrome P450 2A6	1.14.13	0.444
4eue	NAI	Trans-2-enoyl-CoA reductase [NADH]	/	0.444
4ey6	GNT	Acetylcholinesterase	3.1.1.7	0.444
4f1m	ACP	Probable serine/threonine-protein kinase roco4	2.7.11.1	0.444
4ito	MPX	Carbonic anhydrase 2	4.2.1.1	0.444
4qbh	AP5	Adenylate kinase	/	0.444
4zla	BES	Cytosol aminopeptidase	3.4.11.1	0.444
2ycx	P32	Beta-1 adrenergic receptor	/	0.444
1a42	BZU	Carbonic anhydrase 2	4.2.1.1	0.443
1dfo	FFO	Serine hydroxymethyltransferase	2.1.2.1	0.443
1e7q	NAP	GDP-L-fucose synthase	/	0.443
1eqb	FFO	Serine hydroxymethyltransferase	2.1.2.1	0.443
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.443
1m2q	MNX	Casein kinase II subunit alpha	2.7.11.1	0.443
2ab8	MTP	Adenosine kinase	2.7.1.20	0.443
2jds	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.443
2pnu	ENM	Androgen receptor	/	0.443
2trs	PLS	Tryptophan synthase beta chain	4.2.1.20	0.443
2w6z	L21	Biotin carboxylase	6.3.4.14	0.443
2xlr	NAP	Putative flavin-containing monooxygenase	/	0.443
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.443
3dhc	CYK	N-acyl homoserine lactonase AiiA	3.1.1.81	0.443
3dog	NNN	Cyclin-dependent kinase 2	2.7.11.22	0.443
3fhx	PXL	Pyridoxal kinase	2.7.1.35	0.443
3gyt	DL4	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.443
3lst	SAH	CalO1	/	0.443
3n0y	APC	Adenylate cyclase 2	/	0.443
3s41	S41	Glucokinase	2.7.1.2	0.443
3wo0	ADP	Alanine--anticapsin ligase	/	0.443
4h97	53S	Dihydrofolate reductase	1.5.1.3	0.443
4j8t	DOG	Uncharacterized PhzA/B-like protein PA3332	/	0.443
4rh1	0TT	Spore photoproduct lyase	/	0.443
4u07	ATP	Adenosine monophosphate-protein transferase FICD	2.7.7.n1	0.443
4x7v	MIV	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.443
1ay0	TPP	Transketolase 1	2.2.1.1	0.442
1dmy	AZM	Carbonic anhydrase 5A, mitochondrial	4.2.1.1	0.442
1h65	GDP	Translocase of chloroplast 34	3.6.5	0.442
1rfq	LAR	Actin, alpha skeletal muscle	/	0.442
1uda	UFG	UDP-glucose 4-epimerase	5.1.3.2	0.442
2d3a	ADP	Glutamine synthetase root isozyme 3	6.3.1.2	0.442
2r59	PH0	Leukotriene A-4 hydrolase	3.3.2.6	0.442
3b1j	NAD	Glyceraldehyde-3-phosphate dehydrogenase	/	0.442
3c36	KAI	Glutamate receptor ionotropic, kainate 1	/	0.442
3eft	3BS	Carbonic anhydrase 2	4.2.1.1	0.442
3hwx	TPP	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	/	0.442
3lkh	LT6	Genome polyprotein	2.7.7.48	0.442
3sh2	5DR	Dihydrofolate reductase	1.5.1.3	0.442
3sl2	ATP	Sensor histidine kinase WalK	/	0.442
3wv9	FEG	Hmd co-occurring protein HcgE	/	0.442
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.442
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.442
4biw	ANP	Sensor histidine kinase CpxA	/	0.442
4g67	SAH	Uncharacterized ACR, COG1565 superfamily	/	0.442
4ho6	UTP	Glucose-1-phosphate thymidylyltransferase	/	0.442
4q71	FAD	Bifunctional protein PutA	/	0.442
5a65	TPP	Thiamine-triphosphatase	3.6.1.28	0.442
5fd8	A5A	Putative carboxypeptidase yocD	/	0.442
1bws	NDP	GDP-L-fucose synthase	/	0.441
1e8w	QUE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
1ib0	FAD	NADH-cytochrome b5 reductase 3	1.6.2.2	0.441
1k5d	GNP	GTP-binding nuclear protein Ran	/	0.441
1q6y	COA	Formyl-CoA:oxalate CoA-transferase	/	0.441
1srf	MTB	Streptavidin	/	0.441
1xh6	R94	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
1zg3	2HI	Isoflavone 4'-O-methyltransferase	/	0.441
2a0w	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.441
2brh	DFW	Serine/threonine-protein kinase Chk1	2.7.11.1	0.441
2c1b	CQP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
2cah	NDP	Catalase	1.11.1.6	0.441
2itx	ANP	Epidermal growth factor receptor	2.7.10.1	0.441
2j9l	ATP	H(+)/Cl(-) exchange transporter 5	/	0.441
2v59	LZK	Biotin carboxylase	6.3.4.14	0.441
2vmy	FFO	Serine hydroxymethyltransferase	/	0.441
2xc3	RT8	Steroid C26-monooxygenase	1.14.13.141	0.441
3cqu	CQU	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.441
3d8w	D8W	Carbonic anhydrase 2	4.2.1.1	0.441
3dhe	AND	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.441
3eej	53R	Uncharacterized protein	/	0.441
3ewk	FAD	Sensory box histidine kinase/response regulator	/	0.441
3fwy	ADP	Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein	/	0.441
3gbu	ATP	Uncharacterized sugar kinase PH1459	2.7.1	0.441
3i64	DNA	2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase	/	0.441
3nxx	NDP	Dihydrofolate reductase	1.5.1.3	0.441
3ptz	UDX	UDP-glucose 6-dehydrogenase	1.1.1.22	0.441
3s3v	TOP	Dihydrofolate reductase	1.5.1.3	0.441
3zhs	TD6	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.441
4ilx	1EZ	Carbonic anhydrase 2	4.2.1.1	0.441
4lrr	CF9	Thymidylate synthase	/	0.441
4yau	2AM	NADPH--cytochrome P450 reductase	/	0.441
5iqf	GDP	Bifunctional AAC/APH	2.3.1	0.441
1bnn	AL1	Carbonic anhydrase 2	4.2.1.1	0.440
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.440
2blb	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440
2lfo	GCH	Fatty acid-binding protein, liver	/	0.440
2our	CMP	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
2pkl	DHT	Androgen receptor	/	0.440
2qta	TDP	Pyruvate dehydrogenase E1 component	1.2.4.1	0.440
2vig	FAD	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	1.3.8.1	0.440
2vrb	NAP	Triphenylmethane reductase	/	0.440
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.440
2ym8	YM8	Serine/threonine-protein kinase Chk1	2.7.11.1	0.440
3akl	ADP	Serine/threonine-protein kinase CtkA	2.7.11.1	0.440
3biz	61E	Wee1-like protein kinase	2.7.10.2	0.440
3clb	TMQ	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440
3dha	C6L	N-acyl homoserine lactonase AiiA	3.1.1.81	0.440
3dr1	C5D	Vitamin D3 receptor A	/	0.440
3e92	G6A	Mitogen-activated protein kinase 14	/	0.440
3gwf	FAD	Cyclohexanone monooxygenase	/	0.440
3inv	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440
3otb	DGT	Probable tRNA(His) guanylyltransferase	2.7.7.79	0.440
3pkq	DGT	Glucose-1-phosphate thymidylyltransferase	2.7.7.24	0.440
3t1t	GDP	Probable gliding protein mglA	/	0.440
3upk	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.440
4awg	CI3	Polymerase acidic protein	/	0.440
4bc7	FAD	Alkyldihydroxyacetonephosphate synthase, peroxisomal	2.5.1.26	0.440
4g2j	0WF	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.440
4h3g	10Q	Beta-secretase 1	3.4.23.46	0.440
4jbx	SK7	Thymidine kinase	/	0.440
4jr3	KJR	Epidermal growth factor receptor	2.7.10.1	0.440
4n49	MGT	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1	2.1.1.57	0.440
4p9d	TMP	Deoxycytidylate deaminase	/	0.440
4q93	STL	Tyrosine--tRNA ligase, cytoplasmic	6.1.1.1	0.440
5flt	VJJ	Carbonic anhydrase 2	4.2.1.1	0.440
3sn6	P0G	Beta-2 adrenergic receptor	/	0.440