Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5ds309LPoly [ADP-ribose] polymerase 12.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5ds309LPoly [ADP-ribose] polymerase 12.4.2.301.000
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.597
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.580
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.568
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.564
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.560
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.300.559
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.540
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.533
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.527
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.524
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.523
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.523
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.514
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.494
4bj9UHBTankyrase-22.4.2.300.491
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.486
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.472
4tjy3GNTankyrase-22.4.2.300.467
2zitNADExotoxin A2.4.2.360.463
3b82NADExotoxin A2.4.2.360.463
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.460
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.455
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.455
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.455
4li81XQTankyrase-12.4.2.300.450
4pnmNU1Tankyrase-22.4.2.300.448
1zm4TADExotoxin A2.4.2.360.445
2rcwAAIPoly [ADP-ribose] polymerase 12.4.2.300.442
3b8hNADExotoxin A2.4.2.360.441