sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 1.000 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.527 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.505 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.494 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.487 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.485 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.484 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.484 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.483 | |
| 3qly | 55V | Uncharacterized protein | / | 0.482 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.481 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.480 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.479 | |
| 3aba | FLI | Cytochrome P450 | / | 0.479 | |
| 1e7a | PFL | Serum albumin | / | 0.478 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.478 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.476 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.475 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.474 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.473 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.472 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.472 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.470 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.470 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3cxh | SMA | Cytochrome b | / | 0.468 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.468 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.467 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.467 | |
| 1nde | MON | Estrogen receptor beta | / | 0.466 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.466 | |
| 1ezv | SMA | Cytochrome b | / | 0.465 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 3eej | 53R | Uncharacterized protein | / | 0.464 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.464 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.463 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.463 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.463 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.463 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.463 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.462 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.461 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.461 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.461 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.461 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.460 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1hk5 | T44 | Serum albumin | / | 0.459 | |
| 1kb9 | SMA | Cytochrome b | / | 0.459 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.459 | |
| 2iog | IOG | Estrogen receptor | / | 0.459 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.458 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3lu8 | IQX | Serum albumin | / | 0.458 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.458 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.457 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.457 | |
| 1j7u | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.456 | |
| 1kyo | SMA | Cytochrome b | / | 0.456 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3cx5 | SMA | Cytochrome b | / | 0.456 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.456 | |
| 4ej7 | ATP | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.456 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.456 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.456 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.455 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.455 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.455 | |
| 2yiu | SMA | Cytochrome b | / | 0.455 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.455 | |
| 3up3 | XCA | aceDAF-12 | / | 0.455 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.454 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.454 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.454 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.454 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.454 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.454 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.454 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.453 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.453 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.453 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.453 | |
| 4xwt | U5P | Ribonuclease J | / | 0.453 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.452 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.452 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.452 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.452 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.451 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.451 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.451 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.451 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.451 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.451 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.450 | |
| 2ibz | SMA | Cytochrome b | / | 0.450 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.450 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.450 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.450 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1hk4 | T44 | Serum albumin | / | 0.449 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.449 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.449 | |
| 3eel | 53T | Uncharacterized protein | / | 0.449 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.449 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.448 | |
| 1ysx | 4EB | Serum albumin | / | 0.448 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3eem | 53V | Uncharacterized protein | / | 0.448 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.448 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.448 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.447 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.447 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.447 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.447 | |
| 4iae | 1DX | Alr2278 protein | / | 0.447 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.447 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.446 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.446 | |
| 2j0d | ERY | Cytochrome P450 3A4 | / | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.446 | |
| 4l8u | 9AZ | Serum albumin | / | 0.446 | |
| 1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.445 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.445 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3cse | N22 | Uncharacterized protein | / | 0.445 | |
| 3h1j | SMA | Cytochrome b | / | 0.445 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.445 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.445 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.445 | |
| 1fml | RTL | Retinol dehydratase | / | 0.444 | |
| 1ie4 | T44 | Transthyretin | / | 0.444 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.444 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.444 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.444 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.444 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 4okb | 198 | Androgen receptor | / | 0.444 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.443 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.443 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 3q0g | COA | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.443 | |
| 3qcl | NXV | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.443 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.442 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.442 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.442 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4kod | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.441 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.441 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1sqv | UHD | Cytochrome b | / | 0.441 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.441 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.441 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.441 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.440 | |
| 5dju | FMN | NPH1-2 | / | 0.440 |