scPDB - Distribution of Binding site Similarity values of 5d2e entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5d2e	NAP	MlnE

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5d2e	NAP	MlnE	/	1.000
2g9u	G27	Glycogen phosphorylase, muscle form	2.4.1.1	0.496
4iac	ACP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.493
4s33	ANP	Mitogen-activated protein kinase 1	2.7.11.24	0.489
4bcr	WY1	Peroxisome proliferator-activated receptor alpha	/	0.482
5iqi	GNP	Bifunctional AAC/APH	2.3.1	0.477
2xb5	I7T	Tetracycline repressor protein class D	/	0.474
2z7q	ACP	Ribosomal protein S6 kinase alpha-1	2.7.11.1	0.473
4aux	XTC	Tetracycline repressor protein class D	/	0.470
2fsv	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.467
1q3q	ANP	Thermosome subunit alpha	/	0.466
2xpv	MIY	Tetracycline repressor protein class D	/	0.466
3o7l	ANP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.466
3iae	D7K	Benzaldehyde lyase	/	0.465
3ub5	ATP	Actin, cytoplasmic 1	/	0.465
4oa9	ANP	Protein BRASSINOSTEROID INSENSITIVE 1	2.7.10.1	0.465
4c7k	NAP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.464
4xw4	ANP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.464
3qw4	U5P	Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative	/	0.463
3m13	FAD	Monomeric sarcosine oxidase	1.5.3.1	0.462
5fkl	TDC	Tetracycline repressor protein class D	/	0.462
2cdu	FAD	NADH oxidase	/	0.461
2c54	NAD	GDP-mannose 3,5-epimerase	5.1.3.18	0.458
4ipe	ANP	TNF receptor-associated protein 1	/	0.458
3idb	ANP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.457
2ql6	ADP	Nicotinamide riboside kinase 1	/	0.456
4h2p	FAD	2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase	/	0.456
4j36	FAD	Kynurenine 3-monooxygenase	/	0.454
4jnk	ZHK	L-lactate dehydrogenase A chain	1.1.1.27	0.454
5dac	AGS	Uncharacterized protein	/	0.454
2xpw	OTC	Tetracycline repressor protein class D	/	0.453
2yvw	EPU	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.453
3pb3	SAH	16S rRNA (adenine(1408)-N(1))-methyltransferase	2.1.1.180	0.453
5iqe	GNP	Bifunctional AAC/APH	2.3.1	0.453
1ny3	ADP	MAP kinase-activated protein kinase 2	2.7.11.1	0.452
2ekp	NAD	2-deoxy-D-gluconate 3-dehydrogenase	/	0.452
3x2w	ATP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.452
4die	C5P	Cytidylate kinase	/	0.452
1esm	COA	Pantothenate kinase	2.7.1.33	0.451
1i5b	ANP	Chemotaxis protein CheA	2.7.13.3	0.451
2xrl	DXT	Tetracycline repressor protein class D	/	0.451
3cis	ATP	Universal stress protein Rv2623	/	0.451
3gy0	NAP	NAD(P)-dependent oxidoreductase	/	0.451
3rkr	NAP	Uncharacterized protein	/	0.451
3dga	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.450
3nl6	TPS	Uncharacterized protein	/	0.450
4j2w	FAD	Kynurenine 3-monooxygenase	/	0.450
5c3a	URM	Histo-blood group ABO system transferase	/	0.450
1qlh	NAD	Alcohol dehydrogenase E chain	1.1.1.1	0.449
2w6p	OA4	Biotin carboxylase	6.3.4.14	0.449
2wq6	FAD	RE11660p	/	0.449
3a8w	ATP	Protein kinase C iota type	2.7.11.13	0.449
3oib	FDA	Putative acyl-CoA dehydrogenase	/	0.449
4cox	IMN	Prostaglandin G/H synthase 2	1.14.99.1	0.449
4hnh	NAP	NAD-dependent epimerase/dehydratase	/	0.449
4riy	ANP	Receptor tyrosine-protein kinase erbB-3	2.7.10.1	0.449
1j1c	ADP	Glycogen synthase kinase-3 beta	2.7.11.26	0.448
1nmd	ATP	Major actin	/	0.448
2b56	UTP	RNA editing complex protein MP57	/	0.448
2gu8	796	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.448
2qo7	ANP	Ephrin type-A receptor 3	2.7.10.1	0.448
2y05	NAP	Prostaglandin reductase 1	/	0.448
2yph	QQY	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.448
3hv5	R24	Mitogen-activated protein kinase 14	/	0.448
5iqg	GDP	Bifunctional AAC/APH	2.3.1	0.448
1t9c	1SM	Acetolactate synthase catalytic subunit, mitochondrial	2.2.1.6	0.447
1u2d	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.447
2ydx	NAP	Methionine adenosyltransferase 2 subunit beta	/	0.447
3lu7	IPX	Serum albumin	/	0.447
3x2v	ATP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.447
4abz	T1C	Tetracycline repressor protein class D	/	0.447
4gdp	FAD	Polyamine oxidase FMS1	/	0.447
4nxu	ADP	Mitochondrial dynamics protein MID51	/	0.447
1ju9	NAD	Alcohol dehydrogenase E chain	1.1.1.1	0.446
1qo8	FAD	Fumarate reductase flavoprotein subunit	/	0.446
2h2a	DND	Probable nicotinate-nucleotide adenylyltransferase	/	0.446
2o7o	DXT	Tetracycline repressor protein class D	/	0.446
3m9v	TYD	FAD-dependent oxidoreductase	/	0.446
4iay	ADP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.446
4nxx	GDP	Mitochondrial dynamics protein MID51	/	0.446
1b14	NAD	Alcohol dehydrogenase	1.1.1.1	0.445
1ykd	CMP	Adenylate cyclase	/	0.445
2eud	GCQ	Ribonucleoside-diphosphate reductase large chain 1	1.17.4.1	0.445
2ijg	FAD	Cryptochrome DASH, chloroplastic/mitochondrial	/	0.445
2q4b	NAP	Uncharacterized protein At5g02240	/	0.445
3clb	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.445
3i60	E86	Mitogen-activated protein kinase 1	2.7.11.24	0.445
4b3a	TAC	Tetracycline repressor protein class D	/	0.445
4h4w	NAP	Biphenyl dioxygenase ferredoxin reductase subunit	/	0.445
2c0o	L2G	Tyrosine-protein kinase HCK	2.7.10.2	0.444
2pd7	FAD	Vivid PAS protein VVD	/	0.444
2vo6	M05	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.444
4h4t	FAD	Biphenyl dioxygenase ferredoxin reductase subunit	/	0.444
2ggq	TTP	Dual sugar-1-phosphate nucleotidylyltransferase	/	0.443
3cp9	C19	Vascular endothelial growth factor receptor 2	2.7.10.1	0.443
3d7k	D7K	Benzaldehyde lyase	/	0.443
4fv6	E57	Mitogen-activated protein kinase 1	2.7.11.24	0.443
5bqf	NAP	Probable hydroxyacid dehydrogenase protein	/	0.443
4iaf	ADP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.442
4nxw	ADP	Mitochondrial dynamics protein MID51	/	0.442
5ftc	ADP	TPR domain protein	/	0.442
1okk	GCP	Signal recognition particle protein	/	0.441
1okk	GCP	Signal recognition particle receptor FtsY	/	0.441
2bkj	FMN	NADPH-flavin oxidoreductase	/	0.441
2p9c	NAI	D-3-phosphoglycerate dehydrogenase	1.1.1.95	0.441
2x19	GTP	GTP-binding nuclear protein GSP1/CNR1	/	0.441
3jzd	NAD	Maleylacetate reductase	/	0.441
3v5w	8PR	Beta-adrenergic receptor kinase 1	2.7.11.15	0.441
1a9z	UPG	UDP-glucose 4-epimerase	5.1.3.2	0.440
2rbe	NDP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.440
3giy	FMN	(S)-mandelate dehydrogenase	1.1.99.31	0.440
3nbw	TR4	Ketohexokinase	/	0.440
3o3p	GDD	Glycosyl transferase, family 2	/	0.440
3tqa	NDP	Dihydrofolate reductase	/	0.440
4xgx	ADP	FAD:protein FMN transferase	/	0.440