Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 1.000 | |
| 5ccb | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.576 | |
| 4ymg | SAM | Putative SAM-dependent O-methyltranferase | / | 0.487 | |
| 3t7o | UPG | Glycogenin-1 | 2.4.1.186 | 0.473 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.471 | |
| 2dpm | SAM | Modification methylase DpnIIA | 2.1.1.72 | 0.462 | |
| 3up3 | XCA | aceDAF-12 | / | 0.459 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.458 | |
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 | 0.456 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.450 | |
| 4ft4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.450 | |
| 3ldg | SAH | Uncharacterized protein | / | 0.445 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.443 | |
| 3lga | SAH | tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.219 | 0.442 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.442 |