sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5cb4 | ACP | Tubulin tyrosine ligase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5cb4 | ACP | Tubulin tyrosine ligase | / | 1.000 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.628 | |
| 5ca0 | ACP | Tubulin tyrosine ligase | / | 0.627 | |
| 4zol | ACP | Tubulin tyrosine ligase | / | 0.590 | |
| 4zhq | ACP | Tubulin tyrosine ligase | / | 0.549 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.496 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.496 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.489 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.481 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.479 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.477 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.473 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.470 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 1r2j | FAD | FkbI | / | 0.468 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.466 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.466 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.466 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.466 | |
| 4o4i | ACP | Tubulin tyrosine ligase | / | 0.466 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.465 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.464 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.464 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.464 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.463 | |
| 1cg4 | IMO | Adenylosuccinate synthetase | / | 0.462 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.462 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.461 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.461 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.461 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.460 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.459 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.459 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.459 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.459 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.457 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.457 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.457 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.457 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.457 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.456 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.456 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.456 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.455 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.455 | |
| 1c70 | L75 | Protease | / | 0.454 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.454 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.454 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.454 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.453 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.452 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1mer | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.452 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.452 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.452 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.452 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1gqt | ACP | Ribokinase | / | 0.451 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.451 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.451 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.451 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3u9e | COA | Lmo1369 protein | / | 0.451 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.451 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.451 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.451 | |
| 5la6 | ACP | Tubulin tyrosine ligase | / | 0.451 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2ama | DHT | Androgen receptor | / | 0.450 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.449 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.449 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.449 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.449 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.449 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.449 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.448 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 3wdl | ATP | 4-phosphopantoate--beta-alanine ligase | 6.3.2.36 | 0.448 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.448 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.448 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.447 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.447 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.447 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.447 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4x30 | T44 | Thyroxine-binding globulin | / | 0.447 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.447 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
| 1c6x | 3IN | Protease | / | 0.446 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.446 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.446 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.445 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.445 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.445 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.444 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2ceo | T44 | Thyroxine-binding globulin | / | 0.444 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.444 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.444 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1ida | 0PO | Gag-Pol polyprotein | 3.4.23.47 | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.443 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.443 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.443 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.443 | |
| 4ewh | T77 | Activated CDC42 kinase 1 | / | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.443 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4zas | TYD | CalS13 | / | 0.443 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.442 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.442 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.442 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.441 | |
| 1odw | 0E8 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.441 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3op5 | REB | Serine/threonine-protein kinase VRK1 | 2.7.11.1 | 0.441 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4cfn | JYM | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4o1p | ANP | Ribonuclease L | / | 0.441 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.440 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.440 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.440 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 |