sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5c88 | COA | N-alpha-acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5c88 | COA | N-alpha-acetyltransferase | / | 1.000 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.637 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.628 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.586 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.528 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.528 | |
| 4kub | COA | Uncharacterized protein | / | 0.525 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.524 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.523 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.523 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.521 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.520 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.519 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.506 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.505 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.502 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.501 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.499 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.498 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.498 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.496 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.495 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.493 | |
| 3f8k | COA | Uncharacterized protein | / | 0.493 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.492 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.492 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.492 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.491 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.489 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.487 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.486 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.486 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.485 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.484 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.484 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.483 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.483 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.482 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.480 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.478 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.476 | |
| 3lu8 | IQX | Serum albumin | / | 0.476 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.475 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.475 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.474 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.474 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.474 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.473 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.473 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.473 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.472 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.471 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.471 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.470 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.470 | |
| 6adh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.470 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.469 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.468 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.467 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.467 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.467 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.466 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.465 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.465 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.465 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.465 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.464 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.464 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.463 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.463 | |
| 3stx | BKA | Methylketone synthase I | / | 0.463 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.463 | |
| 4qec | NAP | ElxO | / | 0.463 | |
| 1jut | LYD | Thymidylate synthase | / | 0.462 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 2o12 | FMN | Chorismate synthase | / | 0.462 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.462 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.462 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.461 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.461 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.461 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.460 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.459 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.459 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3lu7 | IPX | Serum albumin | / | 0.459 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 5a3c | NAD | SIR2 family protein | / | 0.459 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.458 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 1ie4 | T44 | Transthyretin | / | 0.456 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.456 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.456 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.456 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.456 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.456 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.456 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.455 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.455 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.455 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.455 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.454 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.454 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.454 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 3zuy | TCH | Transporter | / | 0.454 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.454 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.454 | |
| 4hi0 | GDP | Urease accessory protein UreG | / | 0.454 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.454 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.453 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2j4d | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.453 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.453 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.453 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.453 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 4ava | ACO | Acetyltransferase Pat | 2.3.1 | 0.453 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.453 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.452 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.452 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.452 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.452 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.452 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.452 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.451 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.451 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.451 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.450 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 2e48 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.450 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 4h4w | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.449 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.449 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.449 | |
| 3zia | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 3zux | TCH | Transporter | / | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 2j09 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.448 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.448 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.448 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.447 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1osv | CHC | Bile acid receptor | / | 0.447 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2e9z | UTP | Genome polyprotein | / | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2x5z | GDD | Mannose-1-phosphate guanylyltransferase | / | 0.447 | |
| 3ieu | GDP | GTPase Era | / | 0.447 | |
| 4a62 | ANP | Plasmid segregation protein ParM | / | 0.447 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.447 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.447 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.447 | |
| 4l06 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 1gqt | ACP | Ribokinase | / | 0.446 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.446 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.446 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.446 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.446 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.446 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.446 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.445 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.445 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.445 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.445 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.445 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.445 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.444 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.444 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.444 | |
| 2wq7 | FAD | RE11660p | / | 0.444 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.444 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.444 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.444 | |
| 3gob | HXX | DdmC | / | 0.444 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.444 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.443 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.443 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.443 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.443 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3mzi | FMN | Activator of photopigment and puc expression | / | 0.443 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.443 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.443 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.443 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ad5 | ADP | CTP synthase | / | 0.442 | |
| 2c6d | ANP | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.442 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.442 | |
| 3cvu | FAD | RE11660p | / | 0.442 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.442 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.442 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.442 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.441 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.441 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.441 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.441 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.441 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.441 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 5a3b | APR | SIR2 family protein | / | 0.441 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.440 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.440 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.440 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.440 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.440 |