Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5ayaX8ZMetallo-beta-lactamase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5ayaX8ZMetallo-beta-lactamase/1.000
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.488
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.459
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3q43D66M1 family aminopeptidase3.4.110.455
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.455
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.453
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.450
3ndjJHZMethyltransferase/0.450
3vt45YIVitamin D3 receptor/0.449
1icpFMN12-oxophytodienoate reductase 11.3.1.420.447
1sq5ADPPantothenate kinase2.7.1.330.445
2o7pNAPRiboflavin biosynthesis protein RibD/0.445
3i0pNADMalate dehydrogenase, putative/0.445
4xo7NAPAldo-keto reductase family 1 member C2/0.445
3e6eDCSAlanine racemase/0.444
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.444
1ez0NAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.442
4q0kGA3Phytohormone-binding protein/0.442
4r81FMNPredicted NADH dehydrogenase/0.442
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.441
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.440
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440