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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5ap7SVEDual specificity protein kinase TTK2.7.12.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5ap7SVEDual specificity protein kinase TTK2.7.12.11.000
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.495
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.474
1qmzATPCyclin-dependent kinase 22.7.11.220.451
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.444
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.443
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.442
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.441
1i44ACPInsulin receptor2.7.10.10.440