sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5adv | DBS | Enterochelin uptake periplasmic binding protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5adv | DBS | Enterochelin uptake periplasmic binding protein | / | 1.000 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.468 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.458 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.453 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.449 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.447 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.447 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.442 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.441 |