sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4zvp | ASP_GLU_VAL_ACE_ASA | Caspase-7 | 3.4.22.60 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4zvp | ASP_GLU_VAL_ACE_ASA | Caspase-7 | 3.4.22.60 | 1.000 | |
| 4zvr | ASP_GLU_VAL_ACE_ASJ | Caspase-7 | 3.4.22.60 | 0.590 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.475 | |
| 3r7n | ASP_VAL_ALA_ACE_ASA | Caspase-2 | 3.4.22.55 | 0.460 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.453 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.449 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.445 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.444 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.444 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 5dp2 | NAP | CurF | / | 0.443 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3qof | GDP | Atlastin-1 | 3.6.5 | 0.442 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.440 |