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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4zm3PLPAminotransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4zm3PLPAminotransferase/1.000
2getCOKPantothenate kinase2.7.1.330.464
3af3GCPPantothenate kinase2.7.1.330.458
3af0GDPPantothenate kinase2.7.1.330.456
3af4GCPPantothenate kinase2.7.1.330.450
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.447
2eixFADNADH-cytochrome b5 reductase/0.444
4ba5PXGProbable aminotransferase/0.442
1tv8SAMGTP 3',8-cyclase4.1.99.180.441
2zsdCOAPantothenate kinase2.7.1.330.441
3af2ACPPantothenate kinase2.7.1.330.440