sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 1.000 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.598 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.596 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.584 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.579 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.578 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.575 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.573 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.572 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.570 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.568 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.568 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.565 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.563 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.561 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.555 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.553 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.550 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.549 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.547 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.539 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.539 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.515 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.512 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.500 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.499 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.485 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.483 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.476 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.473 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.472 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.472 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.472 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 1r2j | FAD | FkbI | / | 0.471 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1qy5 | NEC | Endoplasmin | / | 0.467 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.467 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4okx | 198 | Androgen receptor | / | 0.467 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.467 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.466 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.466 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.466 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.464 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.463 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.463 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.463 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3v49 | PK0 | Androgen receptor | / | 0.462 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.462 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.461 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.461 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.459 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.459 | |
| 2e1t | MLC | Anthocyanin malonyltransferase homolog | / | 0.459 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.459 | |
| 1ppj | ANY | Cytochrome b | / | 0.458 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.458 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.458 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3v4a | PK1 | Androgen receptor | / | 0.458 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.457 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.456 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.455 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.455 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.455 | |
| 1eio | GCH | Gastrotropin | / | 0.454 | |
| 1qy8 | RDI | Endoplasmin | / | 0.454 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.454 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.454 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.454 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
| 4l4x | NDP | AmphI | / | 0.454 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.454 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.454 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1u0z | RDC | Endoplasmin | / | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.453 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.453 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.453 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.452 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.451 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.451 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 5a3c | NAD | SIR2 family protein | / | 0.450 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.449 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.449 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.448 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.448 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.448 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.448 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1u0y | PA7 | Endoplasmin | / | 0.447 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3gob | HXX | DdmC | / | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.446 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.446 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.446 | |
| 4irn | FAD | AnaB | / | 0.446 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.446 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.445 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 4ozn | ATP | Ammonium transporter | / | 0.445 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 1e7a | PFL | Serum albumin | / | 0.444 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.444 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.444 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.444 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.444 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.444 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.444 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 1flm | FMN | FMN-binding protein | / | 0.442 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.442 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 4i5i | 4I5 | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.442 | |
| 4ok1 | 198 | Androgen receptor | / | 0.442 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.442 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.441 | |
| 2gqp | PA7 | Endoplasmin | / | 0.441 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 3zuy | TCH | Transporter | / | 0.441 | |
| 4btm | F8E | Tau-tubulin kinase 1 | 2.7.11.1 | 0.441 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.441 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.441 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.441 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ysz | NEC | Endoplasmin | / | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.440 | |
| 3a6r | FMN | FMN-binding protein | / | 0.440 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.440 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.440 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.440 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 |