Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4yutFMNFamily 3 adenylate cyclase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4yutFMNFamily 3 adenylate cyclase/1.000
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.466
5f0a1FBcGMP-dependent protein kinase, putative/0.456
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.455
4yuqKS1Calmodulin-like domain protein kinase/0.452
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.451
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.447
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
2c3qGTXGlutathione S-transferase theta-12.5.1.180.445
2vgoAD5Aurora kinase B-A2.7.11.10.445
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.444
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.444
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.443
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3igoANPCalmodulin-domain protein kinase 1, putative/0.443
3q5iANPProtein kinase, putative/0.442
1tj0FADBifunctional protein PutA1.5.5.20.441
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.441
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.441
4yusFMNFamily 3 adenylate cyclase/0.441
4hh0FMNAppA protein/0.440
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.440