scPDB - Distribution of Binding site Similarity values of 4ypa entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ypa	SAM	Histone-lysine N-methyltransferase ASH1L	2.1.1.43

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4ypa	SAM	Histone-lysine N-methyltransferase ASH1L	2.1.1.43	1.000
4ypu	SAM	Histone-lysine N-methyltransferase ASH1L	2.1.1.43	0.561
4ynp	SAM	Histone-lysine N-methyltransferase ASH1L	2.1.1.43	0.558
4ynm	SAM	Histone-lysine N-methyltransferase ASH1L	2.1.1.43	0.534
3ooi	SAM	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	2.1.1.43	0.441